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Application of acanthopanax fruit extractive in preparing medicament for treating hyperlipoidemia

A technique for acanthopanax senticosus fruit and hyperlipidemia, which is applied in the application field of acanthopanax senticosus fruit extract in the preparation of a drug for treating hyperlipidemia, can solve problems such as unseen hyperlipidemia, and achieves the expansion of drug sources, toxic effects and the like. Small side effects, significant curative effect

Active Publication Date: 2009-11-25
李平亚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] There is no report on the treatment of hyperlipidemia with Acanthopanax fruit extract

Method used

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  • Application of acanthopanax fruit extractive in preparing medicament for treating hyperlipoidemia
  • Application of acanthopanax fruit extractive in preparing medicament for treating hyperlipoidemia
  • Application of acanthopanax fruit extractive in preparing medicament for treating hyperlipoidemia

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0017] Experimental example 1, the influence test of the water extract of Acanthopanax senticosus on mice with hyperlipidemia

[0018] 1. Materials and methods

[0019] 1.1 Animals

[0020] 70 ICR mice, 50 males and 20 females, weighing 18-20g. Purchased from the Animal Experiment Center of Jilin University School of Basic Medicine, animal certificate number: SCXK-(Ji)-2003-0001.

[0021] 1.2 Drugs and reagents

[0022] Xuezhikang Capsules, specification: 300mg / capsule, batch number 20060305, produced by Beijing Beida Weixin Biotechnology Co., Ltd.;

[0023] Fenofibrate group, specification: 200mg / capsule, batch number 89396, produced by French Liboforni Pharmaceutical Company;

[0024] Cholesterol, specification: biochemical reagent, 25g / bottle, lot number: 070516, Tianjin Guangfu Fine Chemical Research Institute;

[0025] Sodium cholate, specification: biochemical reagent, batch number: 20070525, Beijing Chemical Reagent Company;

[0026] Lard, provided by the laborato...

experiment example 2

[0051] Experimental example 2, the effect test of total saponins of Acanthopanax senticosus on mice with hyperlipidemia

[0052] 1. Materials and methods

[0053] 1.1 Animals

[0054] 80 ICR mice, 60 males and 20 females, weighing 18-20g. Purchased from the Animal Experiment Center of Jilin University School of Basic Medicine, animal certificate number: SCXK-(Ji)-2003-0001.

[0055] 1.2 Drugs and reagents

[0056] Xuezhikang Capsules, specification: 300mg / capsule, batch number 20060305, produced by Beijing Beida Weixin Biotechnology Co., Ltd.;

[0057] Fenofibrate group, specification: 200mg / capsule, batch number 89396, produced by French Liboforni Pharmaceutical Company;

[0058] Cholesterol, specification: biochemical reagent, 25g / bottle, lot number: 070516, Tianjin Guangfu Fine Chemical Research Institute;

[0059] Sodium cholate, specification: biochemical reagent, batch number: 20070525, Beijing Chemical Reagent Company;

[0060] Lard, provided by the laboratory;

...

Embodiment 1

[0086] Add 250.0 g of Acanthopanax fruit water extract, add 50 g of starch, mix well and pack into hard capsules to make 1000 capsules, 0.3 g per capsule.

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PUM

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Abstract

The invention relates to the application of an acanthopanax fruit extractive in preparing medicament for treating hyperlipoidemia, belonging to the technical field of medicine. An experimentation shows that the acanthopanax fruit extractive has very good function of treating the hyperlipoidemia, therefore, the acanthopanax fruit extractive can be used for preparing medicament for regulating blood fat, health-care products, food additives or compound preparations, and the like, and is mainly used for preparing the medicament for treating the hyperlipoidemia or improving symptoms of the hyperlipoidemia, wherein the medicament or the health-care products include the prior dosage forms, such as a troche, a capsule, a dripping pill, a pilula, a granular formulation, a soft capsule, a syrup, a chewable tablet, a patch, and the like.

Description

technical field [0001] The invention relates to the application of Acanthopanax japonicus extract in the preparation of medicines for treating hyperlipidemia. Background technique [0002] Acanthopanax fruit is the ripe fruit of Acanthopanax senticosus (Rupr. et Maxim) Harms, a plant of Araliaceae. The dried roots and rhizomes of Acanthopanax senticosus, its stems and leaves have been used as medicine, but there are few studies on its fruit, and there is no report of being used as medicine. Compendium of Materia Medica claims that Acanthopanax is "the top grade in the classics", which can "invigorate the middle and replenish qi, strengthen the muscles and bones, strengthen the will, make light of body and resist aging after long-term use". The medicine is warm in nature, pungent in taste, slightly bitter, non-toxic, and enters the spleen and kidney channels. It can strengthen the body and consolidate the foundation, improve intelligence and calm the nerves. Indications fo...

Claims

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Application Information

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IPC IPC(8): A61K36/254A61P3/06A61K131/00
Inventor 李平亚刘金平卢丹周明娟
Owner 李平亚
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