Method for controlling temperature in the production process of seaweed polysaccharide plant empty capsules
A technology of plant hollow capsules and seaweed polysaccharides, which can be used in capsule delivery, drug delivery, and pharmaceutical formulations. It can solve problems such as incomplete grasp of physical and chemical properties, failure to reach the disintegration time limit, and impact on drug absorption, etc., to avoid technical difficulties and investment, extensive market demand, and high-tech content
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Embodiment 1
[0060] Mix 7 kg of cellulose hydroxypropyl methyl ether and 2 kg of seaweed polysaccharide as a coagulant aid and dissolve them in 80 kg of hot water at 75°C. After stirring well, add 5ml of 0.5% calcium citrate as a coagulant aid . At this time, dissolve 2 kg of hydrolyzed starch of thermoreversible colloid in 20 kg of water, mix it with the above solution after fully dissolving and heat to 70°C, and keep the equilibrium reaction time of 3 Hour. Stop keeping warm after 3 hours. Control the temperature of the glue solution at 45°C, control the temperature of the glue tray of the semi-automatic plant capsule production line at 32°C, and start dipping the glue to form a film. The automatic mold dips the glue in the glue tray for 4 seconds, flips the plate for 4 seconds, and enters the temperature at 32 ℃, the humidity is 35% in the drying tunnel, the drying time is 2 hours. After drying, the mold with the sample is transferred to the film-forming workshop at a room temperatur...
Embodiment 2
[0062] Mix 10 kg of cellulose hydroxypropyl methyl ether and 3 kg of seaweed polysaccharide as a coagulant aid and dissolve them in 80 kg of hot water at 90°C. After stirring well, add 5ml of 0.5% calcium citrate as a coagulant aid . At this time, dissolve 3 kg of hydrolyzed starch of thermoreversible colloid in 20 kg of water, mix well with the above solution after fully dissolving, and heat to 80°C. Under the condition that the equilibrium reaction temperature of the glue solution is maintained at 80°C, the equilibrium reaction time is maintained for 2 Hour. Stop keeping warm after 2 hours. Control the temperature of the glue solution at 55°C, control the temperature of the glue tray of the semi-automatic vegetable capsule production line at 36°C, and start dipping the glue to form a film. The automatic mold dips the glue in the glue tray for 6 seconds, flips the plate for 6 seconds, and enters the temperature at 38 ℃, the humidity is 40% in the drying tunnel, and the dryi...
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