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Application of Chinese medicinal composition in preparation of medicament for resisting myocardial stunning

A composition and traditional Chinese medicine technology, applied in the application field of traditional Chinese medicine composition in the preparation of anti-myocardial stunning drugs, can solve the problem of no specific treatment method for myocardial stunning, achieve the protection of myocardial physiological functions, and alleviate myocardial defects. blood, improve coronary circulation

Active Publication Date: 2010-02-24
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently, there is no specific treatment for myocardial stunning

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Embodiment 1: the preparation of capsule

[0070] a) The raw material drug formula is:

[0071] Ginseng 39.6g Leech 72.6g Wood Beetle 46.2g Frankincense (made) 13.2g

[0072] Radix Paeoniae Alba 33g, Dalbergia 13.2g, Sandalwood 13.2g, Scorpion 19.8g

[0073] Cicada slough 46.2g Centipede 6.6g Borneol 33g Suanzaoren (fried) 33g;

[0074] b) Crushing process of medicinal materials:

[0075] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powdered medicine is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicine powder is less than 30-40 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are pre...

Embodiment 2

[0081] Embodiment 2: the preparation of tablet

[0082] a) The raw material drug formula is:

[0083] Ginseng 66g Leech 52.8g Wood Beetle 46.2g Frankincense (made) 13.2g

[0084] Radix Paeoniae Alba 33g, Dalbergia 13.2g, Sandalwood 13.2g, Scorpion 59.4g

[0085] Cicada slough 46.2g Centipede 6.6g Borneol 33g Suanzaoren (fried) 33g

[0086] b) Crushing process of medicinal materials:

[0087] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powdered medicine is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicine powder is less than 70-90 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are prepare...

Embodiment 3

[0093] Embodiment 3: the preparation of pill

[0094] a) The raw material drug formula is:

[0095] Ginseng 39.6g Leech 66g Wood Beetle 46.2g Frankincense (made) 13.2g

[0096] Radix Paeoniae Alba 33g, Dalbergia 13.2g, Sandalwood 13.2g, Scorpion 46.2g

[0097] Cicada slough 46.2g Centipede 6.6g Borneol 33g Suanzaoren (fried) 33g

[0098] b) Crushing process of medicinal materials:

[0099] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powder after powder is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the powder is 10-20 μm;

[0100] c) Extraction concentration and drying process:

[0101] Add water to extract the volatile oil of Jiangxiang and s...

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Abstract

The invention provides application of Chinese medicinal composition in preparation of medicament for resisting myocardial stunning. The Chinese medicinal composition comprises the following Chinese medicaments such as ginseng, leech, chilopod, scorpion, ground beeltle, cicada ecdysis, red paeony root, borneol and the like. The Chinese medicinal composition has the effects of tonifying qi and invigorating the circulation of blood, and removing stasis and obstruction. Clinical experiments prove that the Chinese medicinal composition can effectively resist myocardial stunning.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular, the invention relates to an application of a traditional Chinese medicine composition in preparing anti-myocardial stunning drugs. Background technique [0002] Myocardial stunning (myocardial stunning), also known as post-ischemic myocardial dysfunction, is seen in a variety of clinical situations, such as coronary angioplasty, instability, cardiac pain and exercise-induced cardiac pain, acute myocardial infarction reperfusion therapy After cardiac surgery, neurogenic myocardial stunning, myocardial stunning after cardioversion. Its pathogenesis is based on the theory of aerobic free radicals and calcium overload-contractile protein degradation. Further research suggests that the molecular basis is the modification of cardiac troponin I. Positive inotropes, oxygen free radical scavengers, and calcium ion antagonists may play a role in alleviating ...

Claims

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Application Information

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IPC IPC(8): A61K36/725A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P9/10A61K31/045A61K35/62A61K35/64A61K35/646A61K35/648
Inventor 安军永李向军王超郑立发
Owner HEBEI YILING MEDICINE INST