High-resolution photoacoustic imaging method based on multi-angle observation

A high-resolution, photoacoustic imaging technology, used in diagnostic recording/measurement, medical science, sensors, etc., can solve the problems of reduced lateral resolution and low lateral resolution of photoacoustic images, and achieve improved sensitivity and dynamic range. The effect of wide application range and strong device adaptability

Active Publication Date: 2010-03-17
HARBIN INST OF TECH AT WEIHAI +1
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Problems solved by technology

[0003] At present, photoacoustic images are limited by the cutting process of arrayed ultrasonic probes, and the lateral resolution of ultrasonic i

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Embodiment Construction

[0042] The specific implementation manners of the present invention will be further described in detail below in conjunction with the accompanying drawings.

[0043] The specific structure of the high-resolution photoacoustic imaging device based on multi-angle observation in the present invention is as follows: figure 1 As shown, the device mainly includes a pulsed laser (1), a multi-element array ultrasonic probe (9), a multi-channel parallel acquisition circuit (10) and a computer (11), and the multi-element array ultrasonic probe (9) faces the biological tissue to be tested. (8), the center of the array element surface is aligned with the center of the biological tissue to be measured, and the multi-element array ultrasonic probe (9), the multi-channel parallel acquisition circuit (10) and the computer (11) are electrically connected in sequence.

[0044] The multi-channel parallel acquisition circuit (10) comprises a main control circuit (101), a TGC amplifier circuit (10...

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Abstract

The invention provides a high-resolution photoacoustic imaging method based on multi-angle observation, which comprises the following steps: when a pulse laser irradiates on biological tissues, producing a photoacoustic signal; simultaneously observing the photoacoustic signal by a multi-element array ultrasonic probe, and collecting, storing and uploading all the collected photoacoustic signals to a computer; quickly reconstructing the photoacoustic image on the computer on the basis of a phased dynamic focusing algorithm and a reverse coordinate transformation algorithm; and realizing the multi-angle observation on the biological tissues to be observed by changing dynamic focusing parameters, and carrying out the data fusion treatment on the images observed from different angles. The method realizes the multi-angle observation on the biological tissues to be observed and effectively enhances the lateral resolution and the signal-to-noise ratio of the image; by adopting a distributedquick reconstruction algorithm on the computer, the method increases the imaging speed and realizes the digitalization of the device; and the method realizes the multi-angle and multi-position imagingon the biological tissues to be observed by using the array probe so as to enhance the adaptability and the application range of the system.

Description

technical field [0001] The invention relates to photoacoustic tomography technology, in particular to a high-resolution photoacoustic imaging method based on multi-angle observation. Background technique [0002] Photoacoustic imaging is a non-destructive medical imaging method developed in recent years, which combines the high contrast characteristics of pure optical imaging with the high penetration characteristics of pure ultrasound imaging. It uses short-pulse laser as the excitation source and photoacoustic signal as the information carrier. According to the principle that different biological tissues have different optical absorption coefficients for specific wavelength lasers and then radiates different intensities of ultrasonic waves, it performs imaging by collecting a group of An imaging method in which photoacoustic signals are processed for image reconstruction to obtain internal structure information of tissues. Photoacoustic imaging technology combines optics ...

Claims

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Application Information

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IPC IPC(8): A61B5/00
Inventor 孙明健马立勇冯乃章沈毅
Owner HARBIN INST OF TECH AT WEIHAI
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