Soft capsule and application thereof
A soft capsule preparation and soft capsule technology are applied in the directions of capsule delivery, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., and can solve the problems that the quality of liquid extracts and oral liquids are not stable enough, and the transportation and carrying are inconvenient. , slow dissolution of tablets, etc., to achieve the effect of accurate dosage, less dosage and rapid disintegration
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Embodiment 1
[0021] Take 40kg of motherwort extract dry powder, pass through a 120-mesh sieve, and dry at 60°C; take 5kg of beeswax and add it to 60kg of salad oil to make a soft capsule dispersion medium; take the sieved dry motherwort extract powder and add it to the dispersion medium , mix and stir evenly in the batching pot, adjust the fineness of the colloid mill and reflux for 10 minutes under the condition of 5 μm, pass through the colloid mill to form a uniformly dispersed suspension, vacuumize, take out the pot, put it in a barrel and seal it, and cool down to make a soft capsule Motherwort feed liquid, stable and ready for use.
[0022] Weigh out 10kg of raw material seaweed polysaccharide glue (purchase the seaweed polysaccharide glue produced by Qinhuangdao Pharmaceutical Capsule Co., Ltd. The seaweed polysaccharide glue produced by this factory has obtained the approval number of the State Food and Drug Administration: Guoyao Zhunzi F20050001), glycerin 4.5kg, Hydroxypropyl me...
Embodiment 2
[0025] Take 60kg of dry motherwort extract powder, pass through a 100-mesh sieve, and dry at 50°C; take 1kg of beeswax and add it to 40kg of salad oil to make a soft capsule dispersion medium; take the sieved dry motherwort extract powder, add it to the dispersion medium, Mix and stir evenly in the batching pot, adjust the fineness of the colloid mill and reflux for 20 minutes under the condition of 5 μm, pass through the colloid mill to form a uniformly dispersed suspension, vacuumize, take out the pot, put it in a barrel, seal it, and cool down to make soft capsules of Motherwort Feed liquid, stable and ready to use.
[0026] Weigh out 11.5kg of raw seaweed polysaccharide glue, 3.5kg of glycerin, and 0.005kg of hydroxypropyl methylcellulose; put them into the preheated glue pot, heat up to 50-60°C, stir evenly, vacuumize, and put them out after passing the inspection. Pack the glue into barrels, stabilize the glue for later use, and obtain the soft capsule material glue.
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Embodiment 3
[0029] Take 35kg of motherwort extract dry powder, pass through a 150-mesh sieve, and dry at 60°C; take 3kg of beeswax and add it to 65kg of salad oil to make a soft capsule dispersion medium; take the sieved motherwort extract dry powder, add it to the dispersion medium, Mix and stir evenly in the batching pot, adjust the fineness of the colloid mill and reflux for 30 minutes under the condition of 10 μm, pass through the colloid mill to form a uniformly dispersed suspension, vacuumize, take it out of the pot, put it in a barrel, seal it, and cool down to make soft capsules of Motherwort Feed liquid, stable and ready to use.
[0030] Weigh out 8.5kg of seaweed polysaccharide gum, 5.5kg of glycerin, and 0.015kg of hydroxypropyl methylcellulose; put it into the preheated glue pot, heat it at 50-60°C, stir evenly, and vacuum it. Put the glue into a barrel, stabilize the glue for use, and obtain the soft capsule material glue.
[0031] Put the above-prepared soft capsule content...
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