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Traditional Chinese medicine compound prepration for treating women menopausal syndrome and preparation method thereof

A compound preparation and syndrome technology, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and pill delivery, etc., can solve the problems of menopausal women's injury, inability to adjust the patient's condition, and ineffectiveness.

Active Publication Date: 2010-06-09
JILIN DESHANG PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its common symptoms include: menstrual cycle disorder caused by ovarian function degeneration; cardiovascular and cerebrovascular diseases caused by metabolic dysfunction; nervous system diseases caused by weakened cerebral cortex inhibition and unstable excitation process. Western medicine treatment of symptoms is mainly aimed at the treatment of various symptoms, such as: 1. Sex hormone therapy, i.e. estrogen / progesterone replacement therapy, which is generally oral estrogen, nylestriol, methyl testosterone, etc., but this therapy has Very obvious gastrointestinal side effects; 2. Drug therapy, that is, taking α2 receptor agonists, β adrenergic blockers, sedative-anti-anxiety agents and antidepressants, etc. These drugs are only for menopausal syndrome However, due to the multiple symptoms of the disease, for example, many patients have gynecological diseases such as irregular menstruation, continuous menstrual dripping, waist and abdomen pain, etc., as well as mental depression, irritability, insomnia, palpitations, palpitations and forgetfulness. and other mental disorders, as well as digestive system disorders such as bloating, belching, and hiccups. Therefore, it is difficult for a single drug to be effective and cannot regulate the patient's condition as a whole, and the side effects of western medicine are large. It is easy to cause other harm to menopausal women

Method used

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  • Traditional Chinese medicine compound prepration for treating women menopausal syndrome and preparation method thereof
  • Traditional Chinese medicine compound prepration for treating women menopausal syndrome and preparation method thereof
  • Traditional Chinese medicine compound prepration for treating women menopausal syndrome and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Composition of prescription raw materials

[0022] Bupleurum 240g, Radix Paeoniae Alba 240g, Polygala 192g, Albizia Julibrissin 192g, Poria cocos 192g, Suanzaoren 192g, Coix seed 192g, Lily 192g, Angelica 72g.

[0023] Weigh the prescribed amount of raw materials, crush them into coarse powder, combine them, add 10 times the amount of water to soak for 24 hours, until the medicinal materials are soaked, decoct and extract 3 times, each time the amount of water is 10 times the weight of the medicinal materials, each decoction Cook for 2 hours, filter, combine the filtrate, concentrate the filtrate under reduced pressure into a thick extract state, add 400g of starch to dilute, make soft material, granulate, dry, granulate, and pack into 150 bags, each bag is about 5g, That is, granules.

Embodiment 2

[0025] Composition of prescription raw materials

[0026] Bupleurum 360g, Radix Paeoniae Alba 360g, Polygala 180g, Albizia Julibrissin 180g, Poria cocos 180g, Suanzaoren 180g, Coix seed 180g, Lily 180g, Angelica 60g

[0027] Weigh the raw material drug of the prescribed amount, crush it into a coarse powder, combine, add 12 times the amount of water and soak for 24 hours, until the medicinal material is soaked, decoct and extract 3 times, the amount of water used for decocting is 12 times and 10 times the weight of the medicinal material respectively. times, 8 times, each decocting time is 1.5 hours, filter, combine the filtrate, the filtrate is concentrated under reduced pressure into a thick extract state, add the required excipients for tablet molding, and press into 1000 tablets according to the conventional tablet making process, namely Get Tablets.

Embodiment 3

[0029] Bupleurum 200g, Radix Paeoniae Alba 200g, Polygala 200g, Albizia Julibrissin 200g, Poria cocos 200g, Suanzaoren 200g, Coix seed 200g, Lily 200g, Angelica 100g

[0030] Take the raw material medicine of recipe quantity, pulverize into coarse powder, merge, add the 80% ethanol of 10 times the amount of medical material weight, soak, reflux extraction for 2 hours, filter, filter residue is reflux extracted once again with 10 times the amount of 80% ethanol, Filtrate, combine two ethanol extracts, concentrate under reduced pressure to obtain extract I; decoct the dregs after ethanol extraction with water 10 times the weight of the medicinal material, extract twice, each time for 1 hour, filter, combine two times of water The decoction was concentrated under reduced pressure to obtain the extract II; the extract I and the extract II were combined, dried in a vacuum, and pulverized into a medicinal powder, which was added appropriate amount of starch, filled into 0.4g hard cap...

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Abstract

The invention relates to a traditional Chinese medicine compound prepration for treating women menopausal syndrome, which is specifically prepared by pharmaceutical raw materials of Chinese thorowax root, white paeony root, thinleaf milkwort root-bark, silktree albizzia bark, Indian buead, spina date seed, coix seed, lancelesf lily bulb and Chinese angelica, and the formula prepares a required oral preparation according to the conventional preparation process by extracting active ingredients through water decoction and adding pharmaceutically acceptable conventional excipients. The traditional Chinese medicine compound prepration has the effects of dispersing stagnated liver qi, strengthening spleen, nourishing yin and tranquillization and has a good conditioning and treating role for the women menopausal syndrome.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for women's climacteric syndrome and a preparation method, belonging to the field of traditional Chinese medicine compound preparations. Background technique [0002] Female climacteric syndrome is a syndrome characterized by endocrine disorders and autonomic dysfunction in women after menopause due to the decline of ovarian function. A series of symptoms in women before and after menopause are mostly caused by mental, emotional, social, family and other factors. The age of onset of the disease tends to be earlier and the incidence rate is increasing, and it has gradually been paid attention to by the society. Its common symptoms include: menstrual cycle disorder caused by ovarian function degeneration; cardiovascular and cerebrovascular diseases caused by metabolic dysfunction; nervous system diseases caused by weakened cerebral cortex inhibition and unstable excitation proc...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61K9/20A61K9/48A61K9/16A61K9/00A61P15/12
Inventor 方鉴
Owner JILIN DESHANG PHARMA