Structured occllusive dressings
A so-called wound care technology, applied in the field of adhesive bandages, can solve the problems of messy wound dressing materials blending, too soft, etc.
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Embodiment 1
[0054] To the Brabender Plasticorder heated to 125°C was added 180g of US white petrolatum, 90g of Elvax 40W (a polyvinyl acetate obtained from Dupont), 15g of mineral oil and 15g of Kraton G 1702 (a di-inlay obtained from Shell Company). Segment copolymer, composed of polystyrene and ethylene propylene copolymer). The composition was mixed for 60 minutes, then the temperature was lowered to 80°C and mixing was continued for another 30 minutes. The agent was applied to the non-woven substrate while continuing to warm (at 80°C) using the consumption method. Place a square about 3 / 4 inch in length in the middle of the 3 / 4 inch x 3 inch adhesive tape. A release film with a low release surface is placed on the tape to cover the surface of the adhesive and ointment. The tape was treated with a standard ethylene oxide sterilizing ring (30 minutes at 175°F) in the presence of water. No ointment oozing or flowing out from the adhesive tape was observed, and no ointment was visible o...
Embodiment 2
[0057] Using the method of Example 1, 210g of white petrolatum, 60g of Elvax 40W, 15g of Kraton G1702 and 15g of lanolin alcohol were spread on the nonwoven substrate. No oozing or running of the ointment was observed. The hydrophilic properties of the test composition were observed by observing the slow absorption of water droplets placed on the coating of this example.
Embodiment 3-6 and comparative Embodiment A
[0059] The following five compositions were prepared according to the method of Example 1, and were also coated on the non-woven substrate.
[0060] Compound
3
4
5
6
A
Kraton G 1702
11.1
7.7
11.5
11.1
--
74.1
76.9
77.0
74.1
83.3
Elvax 40W
14.8
15.4
11.5
11.1
12.5
Elvax 150W
--
--
--
3.7
4.2
[0061] The viscosity of the composition of Example 3 was measured with a Rheometrics RDS 7700 rheometer at 35° C. as a function of shear rate, and the viscosity of the composition of Example 3 was compared with that of white petrolatum. Attached figure 2 A graphic representation of the results of this determination is given. The viscosity increase of 10 factors between white petrolatum and the composition of Example 3 is noted.
[0062] The temperature dependence of the viscosity of the compositions of Example 6 and Comparative Example A was compared, the latter did not contain a "network" polymer. The results of this determination are shown in ...
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Abstract
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