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Flavonoid extract containing schaftoside and application thereof

A technology of schavutoside and extract is applied in the field of flavonoid extracts, which can solve the problems of unreported pharmacological efficacy, failure to clearly determine the content of schavutoside and its biological activity, etc., and achieve the effect of no toxic and side effects.

Inactive Publication Date: 2010-07-14
BEIJING NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Du Shushan et al. isolated 6 flavonoids from Aracea, which were identified by chemical and spectroscopic analysis as: Schaftoside, Isschaftoside, Apigenin-6-C-Galactose-8-C-Arabinoside, Celery Apigenin-6-C-arabino-8-C-galactoside and apigenin-6,8-di-C-glucopyranoside, but the content of schaftoside in their flavonoid extracts could not be determined clearly and its biological activity; other pharmacological effects have not been reported

Method used

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  • Flavonoid extract containing schaftoside and application thereof
  • Flavonoid extract containing schaftoside and application thereof
  • Flavonoid extract containing schaftoside and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0081] Pharmaceutical composition embodiment 1: injection

[0082] Flavonoid extract containing schaftosides 10g

[0083] Benzyl alcohol 10g

[0084]Add water for injection to 1000ml

[0085] Make injection 1000ml altogether.

Embodiment 2

[0086] Pharmaceutical composition embodiment 2: tablet

[0087] Flavonoid extract containing schaftosides 30g

[0088] Starch 100g

[0089] 90g powdered sugar

[0090] Dextrin 80g

[0091] Conventional tableting, 1000 tablets, 0.3g per tablet.

Embodiment 3

[0092] Pharmaceutical composition embodiment 3: capsules

[0093] Flavonoid extract containing schaftosides 30g

[0094] Dextrin 100g

[0095] 90g powdered sugar

[0096] Starch 80g

[0097] A total of 1000 capsules were made.

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Abstract

The invention provides a flavonoid extract containing schaftoside, which is prepared from raw traditional Chinese medicinal herbal materials medicine raw materials. The invention also relates to the application of the flavonoid extract in treating cerebral ischemia. The invention particularly provides a flavonoid extract prepared from the raw medicinal material of rhizoma arisaematisarisaema tuber raw material medicine and an extraction method thereof. The invention also provides a medicinal composition adopting the extract. The extraction method is simple and practical, and the extraction effect is favorable. The medicinal composition has an obvious determined curative effect, which and has a brand new application in the aspect for treating cerebrovascular diseases.

Description

technical field [0001] The present invention relates to a flavonoid extract from raw materials of traditional Chinese medicine, in particular to a flavonoid extract containing schaftoside from the raw material of Araceae; the present invention also relates to the application of such extracts in the treatment of cerebral ischemic diseases And the pharmaceutical composition containing the extract. Background technique [0002] "Pharmacopoeia of the People's Republic of China" 2005 Edition, a statutory medicinal Aracea is the Araceae Araceae plant Arisaema erubescens (Wall.) Schott, A.heterophyllum Blume, and A.amurense Maxim. Dry the tubers. Tiannanxing and Heterophyllus have the widest distribution range, almost all over the country. This product has bitter taste, pungent, warm in nature, poisonous. It is a commonly used medicine for drying dampness and reducing phlegm, dispelling wind and relieving spasm, dissipating stagnation and reducing swelling. It is used for persis...

Claims

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Application Information

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IPC IPC(8): A61K36/8884A61P9/10A61K31/352
Inventor 杜树山张海鸣沈圣民曹杰方睿史培军
Owner BEIJING NORMAL UNIVERSITY
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