Light stimulation device

A technology of light stimulation and optical axis, applied in optics, methods of stress-stimulating microbial growth, optical components, etc., can solve the problems of not proposing the concept and description of light uncaging and light stimulation, the system is not compact enough, and it is inconvenient to integrate. , to ensure the quality of beam scanning, compact construction and easy integration

Inactive Publication Date: 2010-07-14
HUAZHONG UNIV OF SCI & TECH
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Problems solved by technology

However, in these patent documents, two acousto-optic deflectors are introduced into the converging optical path through two sets of 4f systems, making the system huge; the system uses a non-optical fiber method to introduce laser light into the scanning unit, making the system not compact enough, inconvenient to integrate, and miniaturized ; In addition, these patents did not propose the concepts and descriptions of light uncaging and light stimulation, nor did they explain the methods, processes, and operations of light stimulation

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Embodiment Construction

[0023] The present invention is described in more detail below by means of examples, but the following examples are only illustrative, and the protection scope of the present invention is not limited by these examples.

[0024] Such as figure 1 As shown, the random photostimulation device provided by the present invention includes a laser 1 , a scanning unit 2 , a lens 3 and a sample stage 4 .

[0025] figure 1 , the optical axis centers of the laser 1, the scanning unit 2, and the lens 3 coincide, the center of the scanning unit 2 is located at the focal plane of the object side of the lens 3, and the sample stage is located at the focal plane of the image side of the lens 3. The scanning unit 2 is composed of two orthogonally placed acousto-optic deflectors (AOD).

[0026] The acousto-optic deflector is a beam scanning device. By applying a sinusoidal signal to its transducer (not shown), the refractive index of its crystal can form a periodic distribution, thereby forming...

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Abstract

The invention discloses a light stimulation device, which can be applied to the fields of biology, chemistry, life sciences and the like. The structure of the device is that a laser, a scanning unit and a lens are arranged sequentially and are coincident with the center of an optical axis; the center of the scanning unit is positioned on an object focal plane of the lens; and the scanning unit comprises two acousto-optic deflection devices arranged orthogonally. The device adopts the acousto-optic deflection devices as the scanning elements and can carry out high-speed random light stimulation on cell biological samples comprising nerve cells, tissues and the like so as to carry out various psychological research. The device adopts the optical fiber and the optical fiber bundle to guide light to make the system miniaturized and convenient for integration, and is very convenient to carry out cooperative work with other systems such as the microscope and the patch clamp.

Description

technical field [0001] The invention relates to a light stimulation device, which can be applied in the fields of biology, chemistry, life science and the like. Background technique [0002] The development of optical technology, especially laser technology, has greatly promoted the progress of society, and the combination of laser technology and biotechnology has provided new ideas and new ways for humans to understand and reveal the mysteries of life. [0003] In 1978, Hoffman Adams proposed that molecules can be caged to inhibit their molecular activity, and the concept of caged was proposed for the first time. In 1993, Adams et al. believed that many substances-photosensitive caged molecules have their caged compounds, also known as photolabile caged compounds, which are artificially synthesized compounds that modify biologically active molecules with hidden groups. When it is in a caged state, its function is closed; when it is exposed to a specific wavelength of light...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G02B21/00G02F1/11C12M1/42
CPCC12M31/06C12M31/04C12M35/02
Inventor 骆清铭曾绍群刘亚丰吕晓华
Owner HUAZHONG UNIV OF SCI & TECH
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