Composition injection of glycerol and fructose and preparation method thereof

Abstract

The invention relates to a composition injection of glycerol and fructose and a preparation method thereof. The composition injection of the glycerol and the fructose comprises the following main ingredients: 25-40 parts of glycerol, 3-8 parts of fructose, 3-13 parts of maltitol and 80-120 parts of water for injection. The composition injection of glycerol and fructose is prepared according to the following steps: (1) liquid preparation: dissolving the main materials and auxiliary materials into proper amount of water for injection to prepare solution, respectively stirring evenly, mixing the prepared solution evenly by stirring, and using a pH regulator to regulate pH to be 4 to 5, wherein hydrochloric acid or sodium hydroxide is preferred as the pH regulator, and filtering to obtain filtrate; (2) sterilization: carrying out high-temperature sterilization on the filtrate in the step (1), and taking proper amount of active carbon for high-temperature sterilization; and (3) decolorization: adding the medical active carbon after high-temperature sterilization into the filtrate after high-temperature sterilization, decolorizing and filtering.

Description

A kind of glycerol-fructose composition injection and preparation method thereof technical field The invention relates to the field of medicine, in particular to a glycerol-fructose composition injection and a preparation method thereof. Background technique Cerebrovascular disease, traumatic brain injury, brain tumor, intracranial inflammation and other causes of acute and chronic increased intracranial pressure are common clinical diseases. At present, the commonly used therapeutic drug in clinic is glycerol fructose injection. Glycerin-fructose injection, which is currently on the market, is a colorless and clear liquid, and its main components are glycerin and fructose. Glycerin Fructose Injection is an osmotic dehydrating agent, through high osmotic dehydration, it improves brain metabolism, reduces brain water content, reduces intracranial pressure and improves cerebral blood flow. It can also be used to reduce the pressure in the anterior chamber and lens. The e...

AI Technical Summary

Problems solved by technology

This method still adds a large amount of glucose, and this still makes this preparation contain more harmful substances, and stability is poor

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