Medicament and coating composition
A drug coating and composition technology, which is applied in the field of drug coating compositions whose peculiar smell is not easy to be noticed by users, can solve the problems of increasing production costs and process complexity, long residence time of coating compositions, and affecting mechanical properties of coatings, etc. problems, to achieve the effect of simplifying the coating prescription and preparation process, promoting drug dissolution, improving mechanical properties and other properties
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0256] A coating (A) made of 60% cellulose acetate, 28% cellulose acetate diethylaminoacetate and 12% thaumatin coats the drug granules, which are Acetaminophen (APAP) Granules. Then the coated drug granules and other ingredients are mixed to form a dry suspension or compressed into tablets for pharmaceutical use. Replace 12% of Thaumatin in the paint (A) with 12% of Triethanolamine, and keep the other things unchanged, and prepare Reference Substance 1 in the same way.
Embodiment 2
[0258] Coating (B) made of 58% Eudragit NE30D, 27% Eudragit E 100, and 15% dicalcium triglycyrrhizinate coated drug particles, which were acetaminophen (APAP) particles. Then the coated drug granules and other ingredients are mixed to form a dry suspension or compressed into tablets for pharmaceutical use. Replace 15% dicalcium triglycyrrhizinate in the coating (B) with 15% triethanolamine, and prepare the reference substance 2 in the same way.
Embodiment 3
[0260] It consists of 54% ethyl cellulose, 26% Eudragit E 100, 10% calcium inosinate (38-74 μm, or 200-400 mesh) and 10% calcium guanylate (38-74 μm, or 200-400 mesh ) coating (C) made to coat the drug granules, the drug granules are sildenafil citrate granules made by dry granulation (particle content: sildenafil citrate 33.3% , microcrystalline cellulose 33%, low-substituted hydroxypropyl cellulose 14.5%, sorbitol 17.2%, silicon dioxide 0.5%, sodium stearyl fumarate 1.5%). Then the coated drug granules and other ingredients are mixed to form a dry suspension or compressed into tablets for pharmaceutical use. Replace the calcium inosinate and calcium guanylate in the paint (C) with 20% talc, and keep the other things unchanged, prepare the reference substance 3 in the same way.
PUM
Property | Measurement | Unit |
---|---|---|
particle size | aaaaa | aaaaa |
diameter | aaaaa | aaaaa |
hardness | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com