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Mugwort extract and preparation process thereof, and application in controlling postmeal gucose

A preparation process and extract technology, applied in the artemisia mugwort extract and its preparation process, as well as in the application field of postprandial blood sugar control, can solve the problems of clinical selection of adverse reactions, high price, poor compliance, etc., to achieve storage and Easy application, low production cost, low cost effect

Inactive Publication Date: 2011-01-05
韩淑英 +5
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the currently clinically used postprandial blood glucose (a-glucosidase inhibitor) controller drugs have problems such as poor compliance, relatively expensive prices, adverse reactions, and limited clinical options. Looking for a safer and more efficient postprandial blood glucose (a-glucosidase inhibitor) -glucosidase inhibitors) Inhibitors have always been a hot spot for researchers from all over the world

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] (1) Preparation process of mugwort water extract: solid-liquid ratio: 1:20, 1:15, 1:15; extraction time: 180min, 120min, 90min.

[0018] (2) Preparation process of mugwort ethanol extract: solid-liquid ratio: 1:15, 1:10, 1:10; ethanol concentration is 60%; extraction time: 120min, 90min, 90min.

Embodiment 2

[0020] (1) Preparation process of mugwort water extract: solid-liquid ratio: 1:17, 1:15, 1:12; extraction time: 150min, 120min, 90min.

[0021] (2) Preparation process of mugwort ethanol extract: solid-liquid ratio: 1:12, 1:10, 1:8; ethanol concentration is 75%; extraction time: 90min, 90min, 60min.

Embodiment 3

[0023] (1) Preparation process of mugwort water extract: solid-liquid ratio: 1:15, 1:15, 1:10; extraction time: 120min, 120min, 120min.

[0024] (2) Preparation process of mugwort ethanol extract: solid-liquid ratio: 1:10, 1:10, 1:8; ethanol concentration is 95%; extraction time: 90min, 60min, 60min.

[0025] The preparation process of each embodiment is as follows:

[0026] ①Example 1, preparation process of mugwort water extract: Artemisia argyi (Aremisia argyi) mugwort leaves or natural dry matter of mugwort leaves and mugwort stems, after crushing, add deionized water 20 times the quality of mugwort Soak overnight→heat reflux at 90°C for 180 min→filter, add 15 times deionization to the filter residue→heat reflux at 90°C for 120 min→filter, add 15 times deionization to the filter residue→heat reflux at 90°C for 90 min→filter. Combine the filtrate three times, concentrate to 1 / 4-1 / 5 of the original liquid at 80°C → adjust the pH to 5-6 with a separating agent (2%-3% glacial...

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PUM

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Abstract

The invention relates to a mugwort extract, a new application thereof and a preparation process thereof, especially a mugwort extract and a preparation process thereof and application thereof in controlling postmeal gucose. The technical scheme comprises: keeping active ingredients of water or ethanol extract of mugwort leaf or mugwort leaf and mugwort stem, and removing useless dregs; applying the mugwort extract to controlling the postmeal gucose in the field of diabetes mellitus prevention and treatment drugs and health food. The invention has the advantages that resources are rich, economic and easy to obtain; the preparation process is simple, low in cost, short in production period, suitable for industrial production, convenient in application, obvious in effect, low in dosage and convenient to carry, store and use. The extract is applied to treating animal diabetes mellitus model, thereby obviously reducing postmeal gucose, improving insulin resistance and decreasing the typical symptoms of diabetes; thus, the invention has remarkable advantage in reducing and deferring diabetic complications and development thereof. Furthermore, the invention shows that the mugwort preparation has good prevention effect on diabetes and diabetic complications. The invention meets the requirements of modern traditional Chinese medicines for triple effects, triple low aspects and triple convenience aspects.

Description

technical field [0001] The invention relates to a mugwort extract and its new application, and a preparation method of the mugwort extract, in particular to the mugwort extract, its preparation process and its application in controlling postprandial blood sugar. Background technique [0002] Diabetes has become one of the three major diseases in the world. With the improvement of people's living standards, the incidence of population aging, diabetes and obesity is increasing year by year, especially the incidence of type 2 diabetes is higher, which has become a chronic disease that seriously threatens human health. . Diabetes is not only a high incidence rate, but more importantly, it is a complication caused by diabetes. With the prolongation of the course of diabetes, it can lead to blindness, cardiovascular and cerebrovascular diseases, liver function damage, renal failure, neuropathy, limb gangrene and even amputation, coma and other complications, eventually leading to...

Claims

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Application Information

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IPC IPC(8): A61K36/282A23L1/30A61P3/10A61K127/00A61K135/00A23L33/105
Inventor 韩淑英王志路王建行储金秀余红王丽萍
Owner 韩淑英
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