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Medicament for treating chronic cerebral circulation insufficiency and preparation method

A technology for insufficient cerebral blood supply and drugs, applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as the inability to increase the application of blood-activating drugs, excessive growth of yang qi, affecting the spleen and stomach, etc. Good aggregation rate, good treatment, good safety effect

Active Publication Date: 2011-01-12
QIANFOSHAN HOSPITAL OF SHANDONG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These medicines in the prior art, due to the adoption of a variety of medicines for promoting blood circulation and removing blood stasis, take them for a long time, which can easily damage the righteousness and affect the spleen and stomach. Among them, the medicines for nourishing Qi and promoting yang will cause the disadvantages of disturbing liver fire and excessive growth of yang qi
The medicines of the prior art are limited by these unfavorable factors of promoting blood circulation and removing blood stasis and nourishing qi and raising yang, making them more unable to increase the application degree of blood promoting drugs

Method used

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  • Medicament for treating chronic cerebral circulation insufficiency and preparation method
  • Medicament for treating chronic cerebral circulation insufficiency and preparation method
  • Medicament for treating chronic cerebral circulation insufficiency and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The medicine for treating chronic cerebral insufficiency is prepared from the following raw materials by weight: 350g of Danshen, 300g of Codonopsis, 120g of Coptidis Rhizoma, 200g of Chuanxiong, 200g of Curcuma, 300g of Hawthorn, 250g of Seaweed, 200g of Tianma, 300g of Coix Seed and 200g of Curcuma .

[0035] Preparation method: Add Coptidis Rhizome to 8 times its mass of water, decoct for 2 hours, filter, add medicinal dregs to 6 times its mass of water, decoct twice as above, the time is 1.5 hours and 1 hour respectively, and combine 3 Sub-water decoction, concentrated under reduced pressure to a thick paste with a relative density of 1.30-1.35 (measured at 60°C), and set aside; add 9 herbs to 9 medicines of Salvia Miltiorrhiza, Codonopsis, Chuanxiong, Curcuma, Hawthorn, Seaweed, Gastrodia elata, Coix Seed, and Curcuma 8 times the mass of water, decoct for 2 hours, filter, add 9 medicines with 6 times the mass of water, and decoct twice as above for 1.5 hours and 1 ...

Embodiment 2

[0037] The medicine for treating chronic cerebral insufficiency is prepared from the following raw materials by weight: 150g of salvia miltiorrhiza, 100g of codonopsis, 10g of coptis, 20g of chuanxiong, 20g of curcuma, 100g of hawthorn, 100g of seaweed, 20g of gastrodia elata, 100g of coix seed and 20g of turmeric .

[0038] Preparation method: Add Coptidis Rhizome with 4 times its mass of water, decoct for 3 hours, filter, add medicinal dregs with 4 times its mass of water, decoct twice as above for 1.5 hours and 2 hours respectively, combine 3 Sub-water decoction, concentrated under reduced pressure to a thick paste with a relative density of 1.30-1.35 (measured at 60°C), and set aside; add 9 herbs to 9 medicines of Salvia Miltiorrhiza, Codonopsis, Chuanxiong, Curcuma, Hawthorn, Seaweed, Gastrodia elata, Coix Seed, and Curcuma 5 times the mass of water, decoct for 2 hours, filter, add 9 herbs to the dregs of water, decoct 2 times as above, the time is 1.5 hours and 2 hours r...

Embodiment 3

[0040] The medicine for treating chronic cerebral blood supply insufficiency is prepared from the following raw materials by weight: 550g of Danshen, 500g of Codonopsis, 320g of Coptidis Rhizoma, 400g of Chuanxiong, 400g of Curcuma, 500g of Hawthorn, 400g of Seaweed, 400g of Tianma, 500g of Coix Seed and 400g of Curcuma .

[0041] Preparation:

[0042] (1) Add Coptis chinensis into water twice its mass, decoct for 2 hours, filter, add water twice the mass of Coptis chinensis to the dregs, decoct 2 times in the same water as above, combine decoction 3 times, concentrate under reduced pressure to relative Density 1.30~1.35 (measured at 60°C) thick paste;

[0043] (2) Add 9 herbs of Danshen, Codonopsis, Chuanxiong, Curcuma, Hawthorn, Seaweed, Gastrodia elata, Coix Seed, and Curcuma to 2 to 9 times their weight in water, decoct for 2 hours, filter, and add 9 herbs to the dregs Water with twice the amount of medicine, decocted twice as above, combined three decoctions, concentrat...

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Abstract

The invention discloses a medicament for treating the chronic cerebral circulation insufficiency and a preparation method. The medicament comprises salvia, codonopsis, coptis, chuanxiong, zedoary, crataegus, seaweed, gastrodia, coix seed and curcuma as raw materials. The preparation method comprises the following steps of: adding water to the coptis for decoction, concentrating the water decoction into thick paste, adding water to other raw materials for decoction, concentrating the water decoction into thick paste, combing the two pieces of thick paste, adding a suitable amount of dextrin, and uniformly mixing, drying, crushing and pelletizing the mixture. The medicament has the effects of simultaneously removing blood stasis, promoting blood circulation, eliminating phlegm and invigorating spleen, can better treat the arteriosclerosis, remarkably improve the integral of syndrome of intermingled phlegm and blood stasis for the granule fraction of removing blood stasis and promoting blood circulation, has better effects of reducing the whole blood high-shear viscosity, low-shear viscosity, plasma viscosity and platelet aggregation ratio, and has the advantages of high safety and no influence on hemogram, liver and kidney functions and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine. Background technique [0002] Cerebral insufficiency refers to a disease in which various reasons lead to chronic and widespread insufficiency of the brain, causing cerebral ischemia and hypoxia, and a series of clinical manifestations of brain dysfunction. Its clinical manifestations are: motor nerve dysfunction, sensory dysfunction, abnormal mental consciousness, etc. [0003] Clinically, when the cerebral blood flow gradually decreases, the first clinical manifestations are various subjective symptoms. With the further decline of cerebral blood flow, mental symptoms will gradually appear. Only when the cerebral blood flow drops to a considerable degree neurological symptoms and signs. At the same time, with the gradual decline of blood flow, the organic changes of the brain gradually become more obvious. If chronic cerebral insufficiency is not well controlled, under ce...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P9/10
Inventor 李长生杨晓妮程广清韩莹
Owner QIANFOSHAN HOSPITAL OF SHANDONG
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