Novel energy-saving process for extracting and purifying panax notoginseng saponins

Abstract

The invention discloses a novel energy-saving process for extracting and purifying panax notoginseng saponins, comprising: crushing raw materials, extracting solvent, cooling and clarifying extraction liquid, concentrating, chromatographically separating and purifying, decoloring, concentrating, evaporating, etc.; the steps are specifically as follows: pre-processing the pseudo-ginseng raw materials and then feeding into an extracting tank, adding 5-10 times of about 70% of ethanol solution, heating to 75 DEG. C, refluxing and extracting for about 3h; collecting the extraction liquid, cooling and clarifying, performing film concentration and recovering ethanol, stopping concentrating till amount of the permeated ethanol solution is 90% of that of the extraction liquid, evaporating the concentrated solution till to ethanol-free, transferring into a chromatographic column, absorbing the solution by the column, separating and purifying, eluting with 70% of ethanol solution, decoloring the eluent and then leading the eluent into a film concentrator to concentrate, directly feeding the concentrated solution into an evaporator to evaporate and recover the residual ethanol, finally preparing fine extract of the panax notoginseng saponins; through the film concentration process, concentration quantity of thermal evaporation is effectively reduced by 90%, comprehensive energy-saving rate reaches above 80%, absolute recovery rate of the solvent reaches above 90%, and solvent consumption is effectively reduced; thus, the process is evident in energy saving and consumption reducing.

Description

technical field [0001] The invention belongs to the technical field of plant extraction, and specifically relates to the improvement of the traditional extracting and purifying technology of active ingredients of Panax notoginseng, and more specifically relates to a new energy-saving process for extracting and purifying the total saponins of Panax notoginseng. Background technique [0002] The prior art extraction process of notoginseng active ingredient extraction requires at least two evaporation and concentration of the ethanol extract, one is the evaporation and concentration of the crude extract, and the other is the evaporation and concentration of the ethanol eluent of the chromatography column. These two evaporations not only consume a lot of Steam, each ethanol concentration will lose about 20% due to the evaporation of ethanol. Due to the rise in energy prices and the increase in the cost of ethanol solvents, the energy consumption and solvent loss of the existing ...

AI Technical Summary

Problems solved by technology

[0002] The prior art extraction process of notoginseng active ingredient extraction requires at least two evaporation and concentration of the ethanol extract, one is the evaporation and concentration of the crude extract, and the other is the evaporation and concentration of the ethanol eluent of the chromatography column. These two evaporations not only consume a lot of Steam, each ethanol concentration will lose about 20% due to the evaporation of ethanol

Due to the rise in energy prices and the increase in the cost of ethanol solvents, the energy consumption and solvent loss of the existing solvent concentration process account for an increasing proportion of the total extraction cost, making many pharmaceutical companies urgently need to reform the traditional process to adapt to energy saving and consumption reduction economic requirements and environmental requirements for emission reduction

Images