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Chlorine dioxide disinfectant oral spray and preparation method thereof

A technology of chlorine dioxide and mouth spray, which is applied in the fields of disinfectant mouth spray, chlorine dioxide disinfectant mouth spray and its preparation, can solve the problems of slow effect, difficulty in bleaching teeth, unsatisfactory deodorization effect, etc. Achieve fast deodorizing effect

Active Publication Date: 2011-02-16
宋健
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the oral disinfection and sterilization gargles and mouth sprays in the past contain ethanol, quaternary ammonium salts, Chinese herbal medicine extracts, and antibacterial drugs. It is also difficult to have the effect of bleaching teeth

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment one: a kind of preparation method of chlorine dioxide disinfection mouth spray adopts following processing steps, and formula ratio is counted by weight:

[0021] (1) Dissolve 0.15 parts of EDTA disodium and 5 parts of glycerin in 100 parts of purified water to obtain solution A;

[0022] (2) Swell 0.15 parts of Carbomer 934P in solution A for 8 hours to make solution B;

[0023] (3) Add 5 parts of chlorine dioxide aqueous solution with a concentration of 2000ppm in solution B and stir evenly to obtain chlorine dioxide disinfection mouth spray. The stirring speed is 60 rpm and the stirring time is 30 minutes.

Embodiment 1

[0024] The chlorine dioxide disinfection oral spray that embodiment 1 obtains carries out antibacterial test in vitro and shows, kills Pseudomonas aeruginosa, Salmonella choleraesuis in 10 seconds; Kills Escherichia coli, Staphylococcus aureus, Neisseria gonorrhoeae, syphilis in 2 minutes Spirochetes, Trichomonas vaginalis, and Streptococcus faecalis; the killing rate is 99.99%. 5 points to kill HbsAg hepatitis virus and Bacillus subtilis spores, the killing rate is 100%. When to the bacteriostasis test of mould, compared chlorine dioxide aqueous solution and the bacteriostatic effect time of the present invention: around the transparent bacteriostatic circle, after 24 hours of cultivation again, the compound change of chlorine dioxide aqueous solution is fuzzy, and the present invention is still transparent , show that the bacteriostasis time of the present invention obviously prolongs, and this is because the present invention first kills microorganisms the same as the chlor...

Embodiment 2

[0025] Embodiment two: a kind of preparation method of chlorine dioxide disinfection mouth spray adopts following processing steps, and formula ratio is counted in parts by weight:

[0026] (1) Dissolve 0.5 parts of EDTA disodium and 10 parts of glycerin in 200 parts of purified water to obtain solution A;

[0027] (2) Swell 0.5 parts of Carbomer 934P in solution A for 12 hours to make solution B;

[0028] (3) Add 10 parts of chlorine dioxide aqueous solution with a concentration of 2000ppm to solution B and stir evenly to obtain a chlorine dioxide disinfection mouth spray. The stirring speed is 80 rpm and the stirring time is 20 minutes.

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Abstract

The invention relates to a chlorine dioxide disinfectant oral spray and a preparation method thereof. The chlorine dioxide disinfectant oral spray is characterized by comprising the following components in portions by weight: 5-8 portions of chlorine dioxide water solution, 0.15-0.5 portion of carbomer 934P, 5-10 portions of glycerol, 0.15-0.5 portion of disodium edetate and 100-200 portions of purified water. The preparation method comprises the following steps: mixing the disodium edetate, the glycerol and the purified water to obtain a solution A; swelling the carbomer 934P in the solution A to obtain a solution B; and adding the chlorine dioxide water solution to the solution B to obtain the chlorine dioxide disinfectant oral spray. The invention has the advantages of fast and enduring effects of sterilization, disinfection and deodorization, high safety, no toxicity, and broad spectrum and high efficiency for killing microbes in the oral cavity, and has bleaching action on yellow pigment spots on the tooth surface caused by tea drinking, smoking and the like.

Description

technical field [0001] The invention relates to a disinfectant oral spray, in particular to a chlorine dioxide disinfectant oral spray and a preparation method thereof, belonging to the technical field of bactericidal disinfectants. Background technique [0002] In the oral cavity, various microorganisms are easy to accumulate and multiply in the gaps between the tongue taste buds, papillae, teeth, periodontium, and gums. stink. The disinfection and sterilization of the oral cavity are very important preventive measures to prevent the above-mentioned diseases from taking place. Most of the oral disinfection and sterilization gargles and mouth sprays in the past contain ethanol, quaternary ammonium salts, Chinese herbal medicine extracts, and antibacterial drugs. It is also difficult to have the effect of bleaching teeth. Contents of the invention [0003] The object of the invention is to overcome the deficiencies in the prior art, to provide a chlorine dioxide disinfe...

Claims

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Application Information

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IPC IPC(8): A61Q11/00A61K8/22A61K8/81
Inventor 宋健
Owner 宋健
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