Laser oncotherapy system
A tumor treatment and laser technology, applied in the field of laser tumor treatment system, can solve the problems of overheating of tumor surface layer and unpredictable curative effect.
Inactive Publication Date: 2011-03-30
NEW VISION
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Problems solved by technology
Therefore, at present, El-Sayed, Halas, Tong et al. use a single wavelength to target a certain R value system, which will suffer from unpredictable curative effect, limited to the application of small (several millimeters) tumors, and overheating of the tumor surface layer, etc.
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[0071] figure 1 It is a structural schematic diagram of a laser tumor treatment system provided by the present invention. The laser tumor treatment system includes: a laser device 100 with an output wave band of 650-1350nm infrared light, coupled to a transmission fiber 101 via an SMA connector 100-a; the transmission fiber 101 is then connected to a handle 102, which contains The adjustable focus lens group 103 is used to control the spot size and shape (parallel or focused) of the output light 110 of the transmission fiber 101 . The optical fiber output light 110 then transmits its energy to the tumor tissue 120 via a shutter 104 (shutter) controlled by an electronically controlled motor 105 . Wherein the transmission fiber 101 is a multi-mode fiber or a single-mode fiber. The shutter 104 switch can also be manually controlled ( figure 1 not shown). The electronically controlled motor 105 is connected to an automatic temperature control system 107, which includes: a plur...
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Abstract
The invention relates to a laser oncotherapy system, in particular to a laser oncotherapy system which converts an incident light source into heat energy by utilizing the characteristic of surface plasma resonance of nanometer particles to kill tumor cells. The laser oncotherapy system comprises a laser device capable of emitting infrared light waveband, an external transmission optical fiber, a handle, an automatic temperature-control system and a signal feedback device, wherein the signal feedback device generates pulse train output light to achieve the aim of automatic temperature control, so that the raised temperature of a superficial layer of tumor tissue is kept at a constant value; and the three-dimensional curative effect of laser light in biological tissue also can be achieved by the optimal selection of multi-wavelength. The solid laser can emit light continuously or in a pulse mode, the wavelength is between 650 and 1,350 nanometers, and the output power is between 0.01 and 20 watts. Nanometer particles disclosed by the invention comprise nanometer particles which have different sizes and various shapes and are formed by gold, silver or combination of the gold and silver, particularly nanometer gold rods of which the length-width ratio is between 3.0 and 10.0 and polyethylene glycol (PEG) and anti-bodies are modified on the surface.
Description
technical field [0001] The invention relates to a laser tumor treatment system, in particular to a laser tumor treatment system which utilizes the surface plasma resonance (surface plasma resonance) characteristic of nanoparticles to convert incident light sources into heat energy to destroy tumor cells. Background technique [0002] Nanoparticles (nanoparticles) are mostly used in imaging diagnosis, but are rarely used directly in treatment. The technique of converting the incident light source into heat energy to destroy tumor cells through the surface plasma resonance characteristics of nanomaterials is called surface plasma photothermal therapy (SPPT). Since most biological soft tissues have less absorption and scattering of infrared light with a wavelength of 650-1350nm, the tissue penetration depth is deeper than that of visible light (400-600nm), and the direct thermal damage to the tissue is also small. SPPT The optimal wavelength range of laser treatment. [0003]...
Claims
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Inventor 林瑞腾
Owner NEW VISION