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New application of inulin

A technology of inulin and linear chain structure, which is applied in the fields of application, medical preparations containing active ingredients, food preparation, etc.

Active Publication Date: 2011-04-27
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are no reports about inulin lowering uric acid and related complications at home and abroad

Method used

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  • New application of inulin
  • New application of inulin
  • New application of inulin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0147] Main drug: inulin, which is a straight-chain structure fructan with a glucose residue attached to the end of the fructose residue (F), which is composed of furan-configured D-fructose via β-2,1 glycosidic bond dehydration polymer, and A linear polysaccharide with a glucose residue (G) attached to the end of the fructose residue (F); the weight average molecular weight range is 2.07×10 3 ~9.34×10 3 ; the purity (the content of fructan) is above 80%; the content of the inulin monosaccharide and disaccharide is 7%.

[0148] Excipients: Lactose

[0149] Add lactose equivalent to 30% of its weight to the above inulin, and make inulin granules by conventional methods.

Embodiment 2

[0151] Main drug: inulin, which is a straight-chain structure fructan without a glucose residue at the end of the fructose residue (F), with a weight-average molecular weight range of 2.07×10 3 ~9.34×10 3 ; the purity (the content of fructan) is over 93%; the content of the inulin monosaccharide and disaccharide is 8%.

[0152] Excipients: lactose (starch, dextrin, powdered sugar, lactose, mannitol, sorbitol, etc. are well formed)

[0153] The above inulin is added with lactose equivalent to 30% of its weight, and then a lubricant magnesium stearate is added, and the inulin tablet is obtained by compression in a conventional method.

Embodiment 3

[0155] Main drug: inulin, which is a straight-chain structure fructan with a glucose residue at the end of the fructose residue (F) and a straight-chain structure fructan without a glucose residue Mixture, the weight average molecular weight range is 2.07×10 3 ~9.34×10 3 ; the purity (the content of fructan) is over 93%; the content of the inulin monosaccharide and disaccharide is 8%.

[0156] Excipients: Lactose

[0157] The above inulin is added with lactose equivalent to 30% of its weight, and then CMC-Na with a total volume of 2‰~5‰ of the liquid is added, and the inulin oral liquid is prepared by a conventional method.

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PUM

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Abstract

The invention aims to disclose new application of inulin, in particular new application of the inulin in the preparation of medicaments and health-care products for preventing and treating hyperur icemia. The hyperur icemia also comprises high uric acid merged hypertriglyceridemia, high uric acid merged hyperglycemia, high uric acid merged hypertriglyceridemia and hyperglycemia, high uric acid merged hypercoagulable and / or hyperviscosity, and the like. When used for preventing and treating the symptoms, the inulin has high safety and no adverse reaction or toxic and side reactions.

Description

technical field [0001] The invention relates to a new application of inulin, which belongs to the technical field of traditional Chinese medicine. Background technique [0002] Hyperuricemia is a chronic purine metabolic disorder, which means that the urate saturation in the blood is about 70mg / L. The clinical diagnostic criteria for hyperuricemia are: ≥420 μmol / L (70 mg / L) for males and ≥360 μmol / L (60 mg / L) for females. Uric acid is the end product of purine metabolism. Due to the accelerated pace of human life and changes in dietary structure, people’s intake of sugar, fat, and protein has increased significantly. There is a clear upward trend. A large number of epidemiological studies in recent years have shown that the prevalence of hyperuricemia in my country is increasing year by year in all regions and age groups. According to preliminary statistics, the general incidence rate of hyperuricemia in my country is about 10%, that is, about 120 million people suffer fr...

Claims

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Application Information

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IPC IPC(8): A61K31/733A23L1/30A61P19/06A61P3/10A61P3/06A61P7/02A23L33/125
Inventor 张冰刘小青林志健庄红艳李慧
Owner BEIJING UNIV OF CHINESE MEDICINE
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