Chinese pulsatilla root granules for preventing and treating livestock and poultry bacterial diseases and preparation method and premix thereof

A Pulsatilla and granule technology, applied in the direction of antibacterial drugs, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the opportunity of expanding the spread of drug resistance, affecting animal food safety, and the mortality rate of sick livestock and poultry. To prevent bacterial diseases of livestock and poultry, avoid drug residues and drug resistance, and achieve good effects

Active Publication Date: 2011-04-27
BEIJING DABEINONG ANIMAL HEALTH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Drug-resistant bacteria not only weaken the efficacy of antibiotics, prolong the course of the disease, increase the cost of treatment, sometimes cause complications, and even make antibiotics lose their efficacy, resulting in increased mortality of sick livestock and poultry
In addition, the failure of treatment will also lead to long-term infection, thereby increasing the number of infected people, expanding the chance of drug resistance transmission, and exposing a large number of livestock, poultry and even humans to the risk of infection caused by drug-resistant strains
In addition, when chemical antibacterial drugs are used for treatment, the drug ingredients are likely to remain in the livestock and poultry, which affects the safety of animal food and seriously endangers human health.

Method used

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  • Chinese pulsatilla root granules for preventing and treating livestock and poultry bacterial diseases and preparation method and premix thereof
  • Chinese pulsatilla root granules for preventing and treating livestock and poultry bacterial diseases and preparation method and premix thereof
  • Chinese pulsatilla root granules for preventing and treating livestock and poultry bacterial diseases and preparation method and premix thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1 Medicine preparation and use of the present invention

[0028] (1) Weigh raw materials containing the following weights:

[0029] 60 parts of Pulsatilla, 40 parts of Coptidis, 60 parts of Cortex Phellodendri, 60 parts of Purslane, 60 parts of Desmodium, 60 parts of Thistle, 40 parts of Qinpi, and 40 parts of Chunpi.

[0030] (2) add 95% ethanol of 10 times the amount of Pulsatilla chinensis, Coptidis Rhizoma, Cortex Phellodendri, Cortex Chinensis, Cortex Chinensis to 10 times of amount, soak for 30 minutes, reflux and extract twice, each time for 1.5 hours, filter, and the combined filtrate is concentrated to a relative density of 1.05 (60 ℃) clear paste. Add water to decoct the remaining purslane, desmodium, and thistle twice, add 12 times the amount of water for the first time, decoct for 2 hours, add 10 times the amount of water for the second time, decoct for 1.5 hours, filter After passing, the combined filtrate was concentrated to a clear paste with...

Embodiment 2

[0032] Embodiment 2 Medicine preparation and use of the present invention

[0033] (1) Weigh raw materials containing the following weights:

[0034] 20 parts of Pulsatilla, 20 parts of Coptidis, 20 parts of Cortex Phellodendri, 20 parts of Purslane, 20 parts of Desmodium, 20 parts of Thistle, 20 parts of Qinpi, and 20 parts of Chunpi.

[0035] (2) add 95% ethanol of 10 times the amount of Pulsatilla chinensis, Coptidis Rhizoma, Phellodendron Phellodendri, Cortex Chinensis, Cortex Chinensis, soak for 30 minutes, reflux and extract twice, each time for 1.5 hours, filter, and the combined filtrate is concentrated to a relative density of 1.10 (60 ℃) clear paste. Add water to decoct the remaining purslane, desmodium, and thistle twice, add 12 times the amount of water for the first time, decoct for 2 hours, add 10 times the amount of water for the second time, decoct for 1.5 hours, filter After passing, the combined filtrate was concentrated to a clear paste with a relative den...

Embodiment 3

[0037] Embodiment 3 Medicine preparation and use of the present invention

[0038] (1) Weigh raw materials containing the following weights:

[0039] 40 parts of Pulsatilla, 30 parts of Coptidis, 40 parts of Cortex Phellodendri, 40 parts of Purslane, 40 parts of Desmodium, 40 parts of thistle, 30 parts of Qinpi, and 30 parts of Chunpi.

[0040] (2) add 95% ethanol of 10 times of amount to Pulsatilla, Coptidis Rhizoma, Phellodendron Phellodendron, Cortex Chinensis, Cortex Chinensis, soak for 30 minutes, reflux and extract twice, each time for 1.5 hours, filter, and the combined filtrate is concentrated to a relative density of 1.08 (60 ℃) clear paste. Add water to decoct the remaining purslane, desmodium, and thistle twice, add 12 times the amount of water for the first time, decoct for 2 hours, add 10 times the amount of water for the second time, decoct for 1.5 hours, filter After passing, the combined filtrate was concentrated to a clear paste with a relative density of 1....

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Abstract

The invention relates to Chinese pulsatilla root granules for preventing and treating livestock and poultry bacterial diseases and a preparation method, application and a premix thereof, and belongs to the field of veterinary medicines and premixes. The Chinese pulsatilla root granules consist of medicinal components such as Chinese pulsatilla root, golden thread, amur corktree bark, parslane herb, longhairy antenoron herb, common cephalanoplos herb, ash bark and tree-of-heaven ailanthus bark. The granules are suitable for preventing and treating the livestock and poultry bacterial diseases, has the characteristics of definite curative effect, stable preparation and simple preparation process and the like, and is suitable for industrial production. The Chinese pulsatilla root granules also can be added into a feed to prepare a feed for promoting the growth of livestock and poultry, such as the premix, a batch and the like.

Description

technical field [0001] The invention relates to a pulsatilla granule for livestock and poultry bacterial diseases, its preparation method, application and premix, and belongs to the field of veterinary medicine and premix. Background technique [0002] Bacterial diseases of livestock and poultry are the most common diseases of livestock and poultry, such as piglet yellow pullorum, suis streptococcosis, chicken staphylococcus disease, chicken colibacillosis, chicken pullorum, etc. Most of these diseases are treated with antibiotics or chemically synthesized antibacterial drugs. In the case of extensive application of antibiotics and increasing number of new antibiotic varieties, due to poor planning or random use of antibacterial drugs, the speed of bacterial drug resistance and drug loss is gradually accelerated. Florfenicol, which went on the market in 1999, had a drug-resistant rate of 60.8% in 2004; similarly, shortly after ofloxacin went on the market in 1984, the United...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/16A61P31/04
CPCY02A40/70
Inventor 葛冰刘澜王洪彬莫云杜继红葛代兴冯华兵贠桂玲刘钧王海良文波黄建茹谢静勇
Owner BEIJING DABEINONG ANIMAL HEALTH TECH
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