Powder with antibacterial and haemostatic effects and preparation method and applications thereof

A hemostatic powder and reactor technology, applied in the medical and health field, can solve the problems of difficult uniform dispersion, weak sterilization ability, and low water absorption, and achieve the effects of favorable dispersion, strong sterilization ability, and rapid absorption.

Active Publication Date: 2011-05-18
SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this antibacterial and hemostatic powder granule has following deficiency: (1) the silver that is adsorbed on the rush surface is the microparticle silver of zero valence, can only form the silver ion (Ag + ) to sterilize, the monovalent silver ion has weak bactericidal ability due to weak oxidation; (2) the raw material used is silver nitr

Method used

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  • Powder with antibacterial and haemostatic effects and preparation method and applications thereof

Examples

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Effect test

Embodiment 1

[0047] A preparation method of bactericidal hemostatic powder, comprising the following steps:

[0048] (1) Take silver peroxide (Ag 2 o 2 ), put into the reactor, add distilled water, after stirring for 15 minutes, add sulfuric acid dropwise, every 60 minutes of stirring, detect the pH value of the solution, make the pH value to 2, clarify for 2 hours, adjust the silver ion mass fraction to be 0.01% , adding mass fraction in the reactor is 0.3% hydrogen peroxide, stirred for 2 hours, and obtained the mother liquor containing high-valence silver ions;

[0049] (2) get 1kg length and be the rush grass of 2mm, put into the reactor that 100kg contains the mother liquor of high-valence state silver ion after wrapping with screen cloth, stir until rush rush all soaks into the solution containing high-valence state silver ion, place After 10 hours, silver-loaded rushes were prepared;

[0050] (3) taking out the silver-loaded rushes from the screen cloth, squeezing them dry, putti...

Embodiment 2

[0053] A preparation method of bactericidal hemostatic powder, comprising the following steps:

[0054] (1) Take silver oxide (Ag 2 0), put into the reactor, add distilled water, after stirring for 60 minutes, add sulfuric acid dropwise, every 10 minutes of stirring, detect the pH value of the solution, make the pH value to 3.5, clear 2 hours, adjust the silver ion mass fraction to be 1 %, add massfraction in reactor and be 10% hydrogen peroxide, stir 1 hour, make the mother liquor containing high valence state silver ion;

[0055] (2) Get 2kg of rushes with a length of 30mm, put them into a reactor containing 100kg of mother liquor containing high-valence silver ions after wrapping them with screen cloth, stir until the rushes are all soaked into the solution containing high-valence silver ions, and place for 2 hours , to prepare silver-loaded rushes;

[0056] (3) taking the silver-loaded rush out of the screen cloth, squeezing it dry, putting it into an oven, and drying it...

Embodiment 3

[0059] A preparation method of bactericidal hemostatic powder, comprising the following steps:

[0060] (1) Take silver peroxide (Ag 2 o 2 ), put into the reactor, add distilled water, after stirring for 40 minutes, add sulfuric acid dropwise, every stirring for 30 minutes, detect the pH value of the solution, make the pH value to 3, clarify for 6 hours, adjust the silver ion mass fraction to be 0.3% , adding mass fraction in the reactor is 3% hydrogen peroxide, stirred for 1.5 hours to obtain a mother liquor containing high-valence silver ions;

[0061] (2) get 2kg length and be the rush grass of 10mm, soak through 50% ethanol earlier, moisten and squeeze dry process, then put into the reactor that 100kg contains the mother liquor of high-valence silver ion after wrapping with screen cloth, stir Until the rushes are completely soaked into the solution containing high-valent silver ions, stir for 0.5 hours further, and place for 8 hours to obtain silver-loaded rushes;

[00...

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Abstract

The invention provides powder with antibacterial and haemostatic effects and a preparation method and applications thereof. The powder with antibacterial and haemostatic effects comprises silver-carrying aquatic grass, medical acrylic resin and calcium bentonite, wherein silver-carrying aquatic grass is aquatic grass adsorbed with high-valence silver ions. The powder has the following benefits: (1) the powder has strong antibacterial effect; (2) the powder has long-lasting antibacterial effect; (3) the powder can rapidly absorb the water in the blood on the surface of wound, and promote accelerated coagulation of the blood on the surface of wound within a few seconds; and the powder does not agglomerate, which is favorable for dispersion and convenient in application; (4) the powder contains calcium ions which is helpful for wound healing; and (5) the powder has no irritation to human body.

Description

technical field [0001] The invention relates to the medical and health field, in particular to a bactericidal hemostatic powder and a preparation method and application thereof. Background technique [0002] In daily life, people often encounter situations that require sterilization and hemostasis of traumatic wounds or surgical wounds. Wound coverings are usually gauze-like dressings processed from materials such as cotton, burlap, non-woven fabrics, or linen. However, when these gauze dressings are used, wound healing is slow, frequent dressing changes are required, and wound bacterial infection is easy to occur, which brings great misery to patients. [0003] The Chinese patent with publication number CN1123665A discloses an antibacterial and hemostatic powder granule made of long-acting broad-spectrum antibacterial granules. The invention can be directly applied to the wound surface and is convenient to use. But this antibacterial and hemostatic powder granule has fol...

Claims

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Application Information

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IPC IPC(8): A61L15/40A61L15/24A61L15/18A61L15/44A61K33/38A61K47/46A61P7/04A61P17/02
Inventor 蒋华德高培军王红梅曾孔仙
Owner SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
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