Therapy device for inactivating pathogenic microorganisms in in-vivo blood by photodynamic therapy

A photodynamic therapy and pathogenic microorganism technology, applied in the direction of blood circulation treatment, etc., can solve the problems of unstable curative effect and inability to perform real-time regulation, and achieve the effect of stable treatment effect and convenient operation.

Inactive Publication Date: 2011-05-25
INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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  • Abstract
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  • Application Information

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Problems solved by technology

[0008] The present invention aims to solve the technical problem that the curative effect of the device for inactivating pathogenic microorganisms in the body blood by photodynamic therapy is unstabl

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  • Therapy device for inactivating pathogenic microorganisms in in-vivo blood by photodynamic therapy
  • Therapy device for inactivating pathogenic microorganisms in in-vivo blood by photodynamic therapy
  • Therapy device for inactivating pathogenic microorganisms in in-vivo blood by photodynamic therapy

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[0034] The present invention will be described in detail below with reference to the drawings and embodiments. In the present invention, the same components as in the prior art use the same symbols.

[0035] figure 1 It is a three-dimensional structural diagram of the therapeutic device for inactivating pathogenic microorganisms in the blood in the present invention; figure 2 Is a three-dimensional structural diagram of the irradiation chamber of the present invention; image 3 It is a schematic diagram of the structure of the treatment device of the present invention. Such as Figure 1 to Figure 3 As shown, the photodynamic therapy device of the present invention for inactivating pathogenic microorganisms in blood in the body includes a laser light source 19, a fluorescence detector 14 arranged in the housing 1, a photosensitizer pump 15, and a control laser light source power density and photosensitizer The metering control panel 13 and the driving power supply 17 for providi...

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Abstract

The invention discloses a therapy device for inactivating pathogenic microorganisms in in-vivo blood by photodynamic therapy. The device comprises a laser light source, a driving power source, an irradiation cabin and a photosensitizer pump, wherein the driving power source is arranged in a shell for providing electric energy for the therapy device; the irradiation cabin is connected with an extracorporeal circulation channel; the photosensitizer pump is connected with the irradiation cabin; a control panel for controlling the photosensitizer pump and the power density of the laser light source is also arranged in the shell; a fluorescent detector is connected between the control panel and the irradiation cabin; a light source control circuit is connected between the control panel and the laser light source; and the front side face of the shell is provided with an operating panel which is connected with the control panel and the driving power source. Through the therapy device for inactivating the pathogenic microorganisms in the in-vivo blood by the photodynamic therapy, the photodynamic therapy is performed on the blood to inactivate the pathogenic microorganisms in the blood. Since the control panel for controlling the photosensitizer pump and the power density of the laser light source is arranged in the therapy device, the using amount of a photosensitizer and the power density of the laser light source can be adjusted and controlled in real time according to a feedback signal of the fluorescent detector; and the therapy device has stable therapy effect and is convenient to operate.

Description

technical field [0001] The invention belongs to the field of laser medical equipment, in particular to a laser treatment device for inactivating pathogenic microorganisms in blood. Background technique [0002] The photodynamic method of inactivating pathogenic microorganisms is mainly based on the principle that the photosensitizer undergoes a photochemical reaction under laser excitation, and the singlet oxygen or free radicals generated oxidize and damage the molecular structure of the target tissue, thereby inactivating the pathogen. At present, the technology of photodynamic inactivation of pathogenic microorganisms in blood is mainly aimed at in vitro blood tissues, such as plasma products, red blood cell concentrates and white blood cell concentrates. [0003] Chinese patent CN101468206A discloses a "viral inactivation method in extracorporeal circulation blood and its application", which includes the following steps: first, adding an anticoagulant to the whole blood ...

Claims

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Application Information

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IPC IPC(8): A61M1/36
Inventor 李迎新阴慧娟董霞
Owner INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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