Method for preparing medicinal raw material salicin from white willow branch bark

Abstract

The invention discloses a method for preparing a medicinal raw material salicin from white willow branch bark. The method comprises the following steps of: grinding the white willow branch bark; adding 20 to 30 weight percent of quicklime; mixing uniformly; conveying the mixture into an extracting tank; performing reflux extraction for three times by using methanol, wherein each time lasts for 1.5 hours; concentrating the extracting solution under reduced pressure until no alcohol exists; adding water in an amount which is 3 to 6 times that of concentrated solution into the concentrated solution; adjusting the pH value to be 9 to 13; standing for 24 hours; concentrating supernatant liquor under reduced pressure until the specific gravity D is equal to 1.10 to 1.13; adding 95 percent methanol in an amount which is 5 times that of concentrated solution into the concentrated solution; standing for 24 hours; performing alcohol precipitation; concentrating supernatant liquor under reduced pressure until the specific gravity D is equal to 1.10 to 1.13; and drying the concentrated solution by spraying powder to obtain the salicin with the content of 25 percent. In the method, the step of performing alcohol precipitation is added; the salicin with the content of 25 percent is directly separated; and the extraction ratio is increased from 4.3 percent to 9 percent. The method is simple in process and suitable for different scales of production, and the cost is obviously reduced.

Description

technical field [0001] The invention belongs to the extraction and separation technology of plant effective components, and in particular relates to a method for extracting and separating salicin from white willow bark. Background technique [0002] Salicin is a substance contained in the branches or bark of the weeping willow Salix babylonicaL of the Salix family. The extracted salicin has clinical medical properties for treating mild fever, colds, infections, acute and chronic rheumatic discomfort, and headaches. and pain caused by inflammation, and it does not have the potential toxic side effects of Western medicine aspirin on the gastrointestinal tract. Salicin extracted from white willow bark is a substance that has received much attention in the past one or two years. It is known as natural aspirin and has antihypertensive effects. Herbs, Ephedra, Ginger Root and VB 5 Used in combination, it has a good function of losing weight and strengthening the body; used in co...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to overcome the deficiencies of the prior art, such as long time consumption, high cost and low extraction rate, and propose a method for preparing salicin as a medicinal raw material from white willow bark, directly extracting and separating 25% salicin