Traditional Chinese drug composition for treating pelvic inflammatory disease, preparation method, application thereof
A composition and technology for pelvic inflammatory disease, applied in the field of traditional Chinese medicine composition for treating pelvic inflammatory disease and its preparation, can solve problems such as difficulty in antibiotics, lack of adhesion-relieving and pain-relieving effects of antibiotics, poor effect of fibrous tissue and connective tissue, etc.
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Embodiment 1
[0041] Embodiment 1: the preparation of capsule.
[0042] According to the raw material ratio in Table 1 and the conventional method of capsule dosage form, it is prepared into capsules, and the specific methods are as follows:
[0043] Take 10 parts of curcuma and 25 parts of angelica, and use supercritical CO 2 Extract for 1 hour, extraction temperature is 20°C, pressure is 20MPa, and entrainer is 95% ethanol to obtain a supercritical extract, which is clathrated with β-cyclodextrin by the saturated aqueous solution method, and continuously stirred for 3 hours under the condition of 30°C and heat preservation, and the stirring speed is 80 rpm, refrigerated for 24 hours, suction filtered, and dried at 40°C to obtain β-cyclodextrin inclusion compound, which was stored separately;
[0044] The above supercritical CO 2 After the extraction process, the dregs and 6 parts of safflower, 40 parts of Motherwort, 6 parts of Yanhusuo, 10 parts of Wuyao, 10 parts of Dihuang, 20 parts ...
Embodiment 2
[0045] Embodiment 2: Preparation of granules.
[0046] According to the ratio of raw materials in Table 1 and the conventional method of granule dosage form, it is prepared into granules, and the specific method is as follows:
[0047] Take 15 parts of curcuma and 20 parts of angelica, and use supercritical CO 2Extracted for 2 hours, the extraction temperature was 40°C, the pressure was 30MPa, and the entrainer was 95% ethanol to obtain a supercritical extract, which was clathrated with β-cyclodextrin by the saturated aqueous solution method, and stirred continuously for 4 hours under the condition of 50°C heat preservation, and the stirring speed was 100 rpm, refrigerated for 36 hours, suction filtered, and dried at 45°C to obtain β-cyclodextrin inclusion compound, which was stored separately;
[0048] The above supercritical CO 2 After the extraction process, 8 parts of medicinal dregs and safflower, 30 parts of Motherwort, 8 parts of Corydalis Corydalis, 8 parts of Wuyao,...
Embodiment 3
[0049] Example 3: Preparation of tablets.
[0050] Prepare by the raw material proportioning of table 1 and tablet dosage form conventional method, be prepared into tablet, concrete method is as follows:
[0051] Take 20 parts of curcuma and 15 parts of angelica, and use supercritical CO 2 Extracted for 3 hours, the extraction temperature was 60°C, the pressure was 40MPa, and the entrainer was 95% ethanol to obtain a supercritical extract, which was clathrated with β-cyclodextrin by the saturated aqueous solution method, and stirred continuously for 5 hours under the condition of 70°C heat preservation, and the stirring speed was 120 rpm, refrigerated for 48 hours, suction filtered, dried at 50°C, β-cyclodextrin inclusion complex, stored separately;
[0052] The above supercritical CO 2 After the extraction process, 10 parts of medicinal dregs and safflower, 20 parts of Motherwort, 10 parts of Corydalis Corydalis, 6 parts of Wuyao, 20 parts of Dihuang, 10 parts of Polygonum ...
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