Chinese medicinal composition for promoting blood circulation, removing blood stasis, promoting qi circulation and relieving pain and preparation method thereof

A technology for promoting qi and relieving pain, promoting blood circulation and removing blood stasis, applied in the field of traditional Chinese medicine composition for promoting qi and relieving pain and promoting blood circulation and removing blood stasis, can solve the problems of low purity of active ingredients, low extraction efficiency, difficult separation and purification, etc. The effect of high purity and simple extraction process

Active Publication Date: 2011-10-12
湖南恒伟药业股份有限公司
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AI Technical Summary

Problems solved by technology

[0004] Studies have shown that using conventional water extraction and alcohol extraction to extract the active ingredients of Chinese herbal medicines has unsatisfactory results, high paste yield, long time consumption, low extraction efficiency, difficult separation and purification, and low purity of active ingredients.

Method used

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  • Chinese medicinal composition for promoting blood circulation, removing blood stasis, promoting qi circulation and relieving pain and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0013] The weight ratio of components in this example: 15 parts of hawthorn, 15 parts of salvia miltiorrhiza, 15 parts of kudzu root, 2 parts of notoginseng, 2 parts of woody fragrance, 15 parts of dextrin, and 0.5 part of stevioside.

[0014] Preparation: Take Radix Notoginseng and Radix Glycyrrhizae and grind them into fine powders of 150-250 mesh with a micro-powder pulverizer for subsequent use; crush Hawthorn, Salvia Miltiorrhiza, and Pueraria Radix into 60 mesh powders, and extract their effective active ingredients with supercritical carbon dioxide fluid (extraction pressure 35MPa, extract The temperature is 50°C, the extraction time is 2H, the separator pressure is 10MPa, the separator temperature is 40°C, and the carbon dioxide flow rate is 80L / H). After drying, crush the extract into fine powder of 150-250 mesh, mix it with notoginseng, woody powder, appropriate amount of dextrin, and stevioside, make granules, and pack.

[0015] Testing method:

[0016] [Identifica...

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PUM

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Abstract

The invention relates to a Chinese medicinal composition for promoting blood circulation, removing blood stasis, promoting qi circulation and relieving pain and a preparation method thereof. The Chinese medicinal composition comprises the following components in part by weight: 7.5 to 22.5 parts of hawthorn fruit, 7.5 to 22.5 parts of root of red-rooted salvia, 7.5 to 22.5 parts of kudzuvine root, 1 to 3 parts of notoginseng root and 1 to 3 parts of costustoot. The preparation method for granules comprises the following steps of: crushing notoginseng root and costustoot to form 150 to 250-mesh fine powder by using a micro powder crusher for later use; crushing hawthorn fruit, root of red-rooted salvia and kudzuvine root for form coarse powder; extracting active ingredients from the coarse powder by using supercritical carbon dioxide fluid, after extracting, reducing system pressure to normal pressure, and precipitating and separating extracted substances to obtain extractum; and drying the extractum, crushing the extractum to form 150 to 250-mesh fine powder, mixing with the fine powder of notoginseng root and costustoot and proper amount of dextrin and stevioside uniformly to prepare granules, and packaging to obtain the Chinese medicinal composition. The preparation method has a simple production process, and is high in extraction speed, the active ingredients are easy to separate, the Chinese medicinal composition does not have residual toxicity, and is high in purity and good in curative effect, and structures and properties of active substances are not damaged.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for promoting blood circulation, removing blood stasis, promoting qi and relieving pain and a preparation method thereof. Background technique [0002] Volume 15 of "Standards issued by the Ministry of Traditional Chinese Medicine" records a kind of Xinkeshu capsule. Preparation method: take the above five flavors, take Panax notoginseng and woody fragrance, and grind them into fine powder; Hawthorn and Pueraria radiata are soaked in 60% ethanol for 30 minutes, then heated and refluxed twice, the first time is 2.5 hours, the second time is 2 hours, combined with alcohol Extract the liquid, recover ethanol under reduced pressure, concentrate to a relative density of 1.35 (20°C); decoct Danshen in water twice, the first time for 2 hours, and the second time for 1.5 hours, combine the decoction, filter, and concentrate to a relative density of 1.35 (20°C); dry the above two thick pastes ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61P9/10A61P29/00A61K31/7034
Inventor 吕宏再
Owner 湖南恒伟药业股份有限公司
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