Medicament composition for treating pulmonary fibrosis

A technology of pulmonary fibrosis and composition, which is applied in the field of pharmaceutical composition for the treatment of pulmonary fibrosis, can solve the problems of lack of specific treatment, large toxic and side effects of chemical preparations, changes in fibrosis, etc., and achieve improvement of clinical symptoms and quality of life, The effect of clear and obvious effect

Inactive Publication Date: 2011-10-26
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In terms of treatment, the treatment of pulmonary fibrosis is currently limited to non-specific anti-inflammatory, immunosuppressant and glucocorticoids, and its common feature is the lack of specific treatment, and scholars believe: "A large number of antibiotics and hormones are the cause of tissue and organ fibrosis. The latest research resu

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0016] Example 1 Preparation of the medicine of the present invention

[0017] a. Weigh the raw materials; 10g of ginseng, 15g of Salvia miltiorrhiza, 15g of Ginkgo biloba, 15g of Asparagus, 15g of Polygonatum Radix, 15g of Gualou shell, 5g of Angelica sinensis, 5g of Panax notoginseng.

[0018] B, add water to decoct, concentrate, concentrate respectively, prepare oral liquid, wherein, the high dose concentration is 3.0g crude drug / ml, the middle dose concentration is 1.5g crude drug / ml, and the low dose concentration is 0.75g crude drug / ml.

Example Embodiment

[0019] The preparation of embodiment 2 medicine of the present invention

[0020] Take 5g of ginseng, 7.5g of Salvia miltiorrhiza, 7.5g of Ginkgo biloba, 7.5g of Asparagus, 7.5g of Polygonatum chinensis, 7.5g of Gualou shell, 2.5g of Angelica sinensis, 2.5g of Panax notoginseng powder, add water to decoct, filter, and concentrate the filtrate into a clear paste. Add pharmaceutically acceptable auxiliary materials such as dextrin, starch, magnesium stearate, and granulate to prepare granules.

Example Embodiment

[0021] The preparation of embodiment 3 medicine of the present invention

[0022] Take 15g of ginseng, 22.5g of Salvia miltiorrhiza, 22.5g of Ginkgo biloba, 22.5g of Asparagus, 22.5g of Polygonatum radix, 22.5g of Gualou shell, 7.5g of Angelica sinensis and 7.5g of Panax notoginseng powder, add 70% ethanol for reflux extraction, and concentrate the extract into clear paste, add common excipients, granulate, and encapsulate to obtain capsules.

[0023] The beneficial effects of the present invention are demonstrated below through pharmacodynamic tests.

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PUM

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Abstract

The invention provides a medicament composition for treating pulmonary fibrosis. The medicament composition is a preparation prepared from the following active pharmaceutical ingredients by weight: 5-15 parts of ginseng, 7.5-22.5 parts of danshen root, 7.5-22.5 parts of ginkgo leaves, 7.5-22.5 parts of radix asparagi, 7.5-22.5 parts of manyflower solomonseal rhizome, 7.5-22.5 parts of snakegourd peel, 2.5-7.5 parts of angelica and 2.5-7.5 parts of panax notoginseng. The invention also provides a preparation method and application of the medicament composition. The medicament has definite effect, can improve the clinical symptoms and quality of life of the patients with organ fibrosis and has obvious effect.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating pulmonary fibrosis, which belongs to the field of medicines. Background technique [0002] Pulmonary fibrosis (PF) is a major disease that has received a lot of attention from the international medical community. However, the current treatments are lacklustre and toxic side effects are unavoidable. Therefore, it is imperative to seek new treatments including traditional Chinese medicine and the unique advantages of traditional Chinese medicine. . [0003] Studies at home and abroad believe that: "Fibrosis is the root cause of chronic diseases that cannot be cured for a long time, and it is also the main cause of disability and death. Nearly 50% of deaths are related to fibrosis, and the root cause of various chronic lung diseases is that they have fibrosis. Pathological changes.” PF is the most representative, typical and frequent fibrotic disease in organ fibrosis, and its etiology is...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P11/00
Inventor 李戎李翠霞
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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