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Composition containing tranexamic acid, and preparation method and uses thereof

A technology of tranexamic acid and composition, which is applied in the field of compositions containing tranexamic acid, can solve the problems of inconspicuous whitening effect, damage, single function, etc. transparent effect

Active Publication Date: 2012-09-26
KANGMEI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] However, most of the current whitening products are a simple combination of several chemical components with whitening function. The components are unstable, and they do not exert the best whitening effect when they work together, and the function is single, so the products show poor whitening effect. Obvious, or some products have obvious initial effect but not long-lasting, certain irritation and damage to the skin, and unclear whitening mechanism, etc., which have not fundamentally solved the problems of melanin pigmentation and dark yellow complexion
For example, the similar product "Shiseido SHISEIDO Whitening Essence" (HAKU Medicinal Whitening Essence) is a cosmetic with tranexamic acid as the main ingredient. It is a whitening essence designed for the special production and discharge of melanin in the skin, but it does not contain natural fish gelatin, so it is not good in reshaping the skin, relieving dullness, rectifying the texture, making the skin lustrous and transparent, mild in nature, and non-irritating. have advantages

Method used

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  • Composition containing tranexamic acid, and preparation method and uses thereof
  • Composition containing tranexamic acid, and preparation method and uses thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The composition containing tranexamic acid provided by the present invention comprises the following ingredients: tranexamic acid 75g, L-cysteine ​​24g, vitamin C 30g, vitamin B 6 4g, calcium pantothenate 2.4g, isinglass 12g, licorice extract 7g. Its preparation method is as follows:

[0037] 1) Take isinglass block and crush it into very fine powder, take 12g of isinglass fine powder;

[0038] 2) Grind licorice into coarse powder, take 50g of it, add 10 times the amount of water for the first time, decoct for 1.5 hours, add 8 times the amount of water for the second time, decoct for 1 hour, add 7 times the amount of water for the third time, Decoct for 1 hour, combine and concentrate the extracts to about 200ml, after cooling, add 50% H2O dropwise while stirring 2 SO 4 , adjust the pH value to 1, wash the precipitate and dry it at 60°C to obtain 7 g of licorice extract;

[0039] 3) Take the powder of the above seven ingredients, add 25g of starch and 21g of lactose...

Embodiment 2

[0041] The composition containing tranexamic acid provided by the present invention comprises the following ingredients: tranexamic acid 60g, L-cysteine ​​20g, vitamin C 25g, vitamin B 6 3g, calcium pantothenate 2g, isinglass 8g, licorice extract 5g. Its preparation method is as follows:

[0042] 1) Take isinglass block and crush it into very fine powder, take 8g of isinglass fine powder;

[0043] 2) Grind licorice into coarse powder, take 35g of it, add 10 times the amount of water for the first time, decoct for 1.5 hours, add 8 times the amount of water for the second time, decoct for 1 hour, add 7 times the amount of water for the third time, Decoct for 1 hour, combine and concentrate the extracts to about 200ml, after cooling, add 50% H2O dropwise while stirring 2 SO 4 , adjust the pH value to 1, wash the precipitate and dry it at 60°C to obtain 5 g of licorice extract;

[0044] 3) Take the powder of the above seven ingredients, add 78g of starch, 18g of dextrin, and 1...

Embodiment 3

[0046] The composition containing tranexamic acid provided by the present invention comprises the following ingredients: tranexamic acid 80g, L-cysteine ​​30g, vitamin C 40g, vitamin B 6 5g, calcium pantothenate 4g, isinglass 15g, licorice extract 10g. Its preparation method is as follows:

[0047] 1) Take isinglass block and crush it into very fine powder, take 15g of isinglass fine powder;

[0048] 2) Grind licorice into coarse powder, take 80g of it, add 10 times the amount of water for the first time, decoct for 1.5 hours, add 8 times the amount of water for the second time, decoct for 1 hour, add 7 times the amount of water for the third time, Decoct for 1 hour, combine and concentrate the extracts to about 200ml, after cooling, add 50% H2O dropwise while stirring 2 SO 4 , adjust the pH value to 1, wash the precipitate and dry it at 60°C to obtain 10 g of licorice extract;

[0049] 3) Take the powder of the above seven ingredients, add 10g of starch and 6g of lactose,...

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Abstract

The invention provides a composition containing tranexamic acid, which comprises the following components: tranexamic acid, L-cysteine, vitamin C, vitamin B6, calcium pantothenate, fish glue and licorice extract. The composition provided in the invention, compared with the common traditional whitening product, has the properties of good stability and being less susceptible to the temperature environment. The product is mild in nature and non-irritanting, and has obvious efficacy in diluting flecks, whitening the skin and balancing the entire skin white colour. The invention also provides a preparation method of the composition and uses of the composition in preparing personal care products having the effect of whitening the skin.

Description

technical field [0001] The invention relates to a composition containing tranexamic acid, a preparation method and application thereof, and belongs to the field of cosmetics. Background technique [0002] In recent years, the efficacy of cosmetics has been paid more and more attention in this industry, such as removing acne and spots, removing wrinkles, restoring skin elasticity, whitening and brightening skin, etc. At present, freckle-removing and whitening products have been selling well in my country and have a large market. According to relevant information on the beautician.com, my country's beauty market has a large capacity. Among the popularity of beauty items, skin care and maintenance account for 72.2%, freckle removal accounts for 52.6%, and whitening accounts for more than 50%. An authoritative European organization conducted a sample survey of Chinese women aged 25 to 60, and found that the first thing that Chinese women show in the process of skin aging is pig...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/195A61K8/97A61K8/65A61K8/67A61K8/44A61Q19/02A61P17/00
Inventor 马兴田许冬瑾向飞军林楠
Owner KANGMEI PHARMA
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