Supercharge Your Innovation With Domain-Expert AI Agents!

Semi-bionic extraction method of anti-gastric cancer active substances in Chrysanthemum chrysanthemum

A technology of active substances and extraction methods, which is applied in the field of semi-bionic extraction, can solve the problems of unreported anti-tumor components, and achieve the effect of simple and feasible operation method, good anti-gastric cancer effect, and high activity of the extract

Inactive Publication Date: 2011-12-07
ZHEJIANG UNIV OF TECH
View PDF0 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the semi-bionic extraction method is used to separate the anti-tumor components in Chrysanthemum chrysanthemum, which has not been reported so far.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1, a semi-bionic extraction method of anti-gastric cancer active substances in Chrysanthemum chrysanthemum, the following steps are carried out in sequence:

[0021] 1) 1 gram of dried Chrysanthemum chrysanthemum was crushed and passed through a 60-mesh sieve; 8ml of buffer solution I with a pH of 2.0 was added (that is, the ratio of solid to liquid was 1g / 8mL); placed in a 37°C water bath for extraction for 2 hours, the buffer solution 1 selects the glycine-hydrochloric acid buffer solution that pH is 2.0 for use;

[0022] After the extraction, filter and discard the filtrate I.

[0023] 2) Add 10ml of buffer solution II with a pH of 8.0 to the filter residue obtained in step 1) (that is, the ratio of solid to liquid is 1g / 10mL); place it in a water bath at 37°C for extraction for 1 hour, and use pH 8.0 for this buffer solution II Boric acid-borax buffer;

[0024] After the extraction, filter and take the filtrate II; pre-cool the filtrate II at -20°C for ...

Embodiment 2

[0026] Embodiment 2, a semi-bionic extraction method of anti-gastric cancer active substances in Chrysanthemum chrysanthemum, the following steps are carried out in sequence:

[0027] 1) Grind and dry 2 grams of Chrysanthemum chrysanthemum, pass through a 40-mesh sieve; add 20ml of buffer solution I with a pH of 2.2 (that is, the ratio of solid to liquid is 1g / 10mL); place in a water bath at 37.5°C for extraction for 1 hour; the buffer solution 1 selects the phthalic acid-hydrochloric acid buffer solution that pH is 2.2 for use;

[0028] After the extraction, filter and discard the filtrate I.

[0029] 2) Add 24ml of buffer solution II with a pH of 8.18 (that is, a solid-liquid ratio of 1g / 12mL) to the filter residue obtained in step 1); place it in a water bath at 36.5°C for extraction for 2 hours, and use pH 8.18 for the buffer solution II. Disodium hydrogen phosphate-potassium dihydrogen phosphate buffer;

[0030] After the extraction, filter and take the filtrate II; pre...

Embodiment 3

[0032] Embodiment 3, a semi-bionic extraction method of anti-gastric cancer active substances in Chrysanthemum chrysanthemum, the following steps are carried out in sequence:

[0033] 1) Grind and dry 5 grams of Chrysanthemum chrysanthemum, and pass through a 60-mesh sieve; add 60 ml of buffer solution I with a pH of 2.2 (that is, a solid-liquid ratio of 1 g / 12 mL); place in a water bath at 36.5° C. for extraction for 2 hours; the buffer solution 1 selects the disodium hydrogen phosphate-citric acid buffer solution that pH is 2.2 for use;

[0034] After the extraction, filter and discard the filtrate I.

[0035] 2) Add 40ml of buffer II with a pH of 7.8 to the filter residue obtained in step 1) (that is, the ratio of solid to liquid is 1g / 8mL); place it in a water bath at 36.5°C for extraction for 2 hours, and the buffer II is selected to have a pH of 7.8 Potassium dihydrogen phosphate-sodium hydroxide buffer;

[0036] After the extraction, filter and take the filtrate II; p...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a semi-bionic extraction method for an anti-stomach-cancer active substance in Hangzhou white chrysanthemum. The method comprises the following steps of: (1) smashing dry Hangzhou white chrysanthemum, sieving with a sieve of 40-60 meshes, adding a buffer solution I of which the pH is 2.0-2.2, putting into a water bath at the temperature of 36.5-37.5 DEG C and extracting for 1-2 hours, filtering after extraction, and removing a filtrate 1; and (2) adding a buffer solution II of which the pH is 7.8-8.2 into filter residues obtained in the step (1), putting into a water bath at the temperature of 36.5-37.5 DEG C and extracting for 1-2 hours, filtering after extraction to obtain a filtrate II, and drying the filtrate II to obtain a Hangzhou white chrysanthemum anti-stomach-cancer extract.

Description

technical field [0001] The invention relates to a semi-bionic extraction method of anti-gastric cancer active substances in Chrysanthemum chrysanthemum. Background technique [0002] Chrysanthemum chrysanthemum is the dry flower head of chrysanthemum (Chrysanthemum morifolium Ramat.), which is mainly produced in Tongxiang, Zhejiang Province. It is one of the eight famous medicinal materials in Zhejiang Province. It has been proved by modern medicine that it has the effects of stopping dysentery, reducing inflammation, improving eyesight, lowering blood pressure, lowering fat, and strengthening the body. At present, the active ingredients extracted from Chrysanthemum chrysanthemum include chlorogenic acid, volatile oil and flavonoids. The anti-tumor effect of Chrysanthemum chrysanthemum is also one of its important health effects. It has been reported that the volatile oil in chrysanthemum chrysanthemum contains β-elemene, which has broad-spectrum anti-tumor effect. Luteoli...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/28A61P1/00A61P35/00A61K133/00
Inventor 于海宁沈生荣单伟光孙晨
Owner ZHEJIANG UNIV OF TECH
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com