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A kind of preparation technology and use of eye protection sticker

A preparation process and technology of protective stickers, which are applied in the field of surgical eye protection stickers, can solve the problems of closed eyes of patients and weak protective effect of direct eye damage, and achieve good biocompatibility, eye protection, and corneal protection effects

Active Publication Date: 2011-12-28
HANGZHOU JUJIU SCI & BIOTECHNOLOGY CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the patient's eyes cannot be closed, because the film of the transparent part of the product is relatively thin, and the protective effect on direct eye damage is relatively weak; experts from the Department of Anesthesiology at Boston Medical Center in the United States and some ophthalmology experts in my country believe that it is necessary to prevent exposure of patients under general anesthesia. For keratitis or direct damage to the eye, the best way is to close the eye and maintain the local physiological environment of the eye

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Take 4% cross-linked sodium polyacrylate, 1.5% CMC, 0.3% aluminum glycylate, 0.2% EDTA, 0.1% paraben according to the proportion of the formula, and disperse the above ingredients in the stirring state at 15-60rpm in turn. Mix in 15% glycerin to obtain liquid A.

[0036] Take 0.15% tartaric acid and 0.02% K-90 according to the proportion of the formula, and disperse them in an appropriate amount of deionized water under the stirring state of 200-1000 rpm, spread 3% carbomer evenly on the liquid surface, and let it stand for swelling After 12-24 hours, heat and dissolve 1% polyvinyl alcohol, and mix with the former to obtain liquid B.

[0037] Disperse the pre-configured liquid A in the stirring state of 15~60rpm in the liquid B and mix evenly to form a gel matrix. Adjust the pH value to 7.0 with triethanolamine or NAOH, add deionized to 100%, and continue stirring Mix evenly, coat the gel matrix with a coating machine, cut, harden, and pack to obtain the finished produ...

Embodiment 2

[0039] Take 8.5% sodium polyacrylate, 0.03% aluminum glycylate, 0.02% EDTA, 0.5% paraben, and 5% titanium dioxide according to the proportion of the formula. Disperse the above ingredients in 30% humectant in turn under stirring at 15-60rpm and mix well to obtain liquid A.

[0040] Take 0.1% tartaric acid, 0.01% K-90, and 0.4% carbomer according to the proportion of the formula, and disperse them in an appropriate amount of deionized water under the stirring state of 200-1000rpm, and place them for 12-24 hours. 0.1% polyethylene Alcohol is heated and dissolved, and mixed with the former to obtain liquid B.

[0041]Disperse the pre-configured liquid A in the stirring state of 15-60rpm in the liquid B and mix evenly to form a gel matrix. Adjust the pH value to 6.5 with triethanolamine or NAOH, add deionized to 100%, and continue stirring Mix well, apply the hydrogel matrix of the surgical protective sticker, apply the gel matrix on a coating machine, cut, harden, and pack to ob...

Embodiment 3

[0043] Take 6% partially cross-linked sodium polyacrylate according to the formula ratio, 1% CMC, 0.3% aluminum glycylate and 0.3% EDTA, 0.5% paraben, 2% titanium dioxide, and mix the above ingredients under the stirring state of 15-60rpm , sequentially dispersed in 20% moisturizing agent and mixed to obtain liquid A.

[0044] Take 0.4% tartaric acid, 0.01% K-90, and 2% carbomer according to the proportion of the formula, and disperse them in an appropriate amount of deionized water under the stirring state of 200-1000rpm, and place them for 12-24 hours. 0.5% polyethylene Alcohol is heated and dissolved, and mixed with the former to obtain liquid B.

[0045] Disperse the pre-configured liquid A in the stirring state of 15-60rpm in the liquid B to form a gel matrix, adjust the pH value to 6.5-8.0 with triethanolamine or NAOH, add deionized to 100%, Continue stirring and mixing, the hydrogel matrix of the surgical protective sticker is coated on the coating machine, cut, harden...

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PUM

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Abstract

The invention relates to an eye protection plaster which is composed of a supporting layer, a gel layer and an isolating layer. The preparation technique comprises the following steps: evenly mixing and dispersing 4-8.5% of polyacrylic acid polymer, 0-1.5% of CMC (carboxymethyl cellulose), 0.03-0.3% of crosslinking agent, 0.02-0.3% of crosslinking regulator, 0-1% of bacteriostat and 0-5% of filler in 5-30% of humectant to obtain a solution A; evenly dispersing 0.1-0.4% of tartaric acid and 0.01-0.08% of polyvinylpyrrolidone in a proper amount of deionized water, spreading 0.4-3% of carbomer on the liquid surface, standing to swell for 12-24 hours, adding 0.1-1% of polyvinyl alcohol into a proper amount of water, dissolving by heating, and evenly mixing with the previous solution to obtain a solution B; and dispersing the solution A in the solution B to form a gel substrate, regulating the pH value to 6.5-8.0, adding deionized water to 100%, evenly mixing, coating, cutting, hardening and packaging to obtain the finished product. The eye protection plaster is used for protecting eyes of general anesthesia patients and patients in deep coma.

Description

technical field [0001] The invention relates to an eye protection patch, in particular to a surgical eye protection which is applied to patients undergoing general anesthesia and deep coma to prevent and control the occurrence of exposure keratitis, and to prevent and protect the patient's eyes from being damaged by foreign objects. stick. Background technique [0002] In our country, tens of thousands of patients need general anesthesia for various reasons every year. The patient is injected with various anesthetics and intramuscular drugs. After reaching a deep anesthesia, the patient does not feel pain and the muscles relax. Although this situation is conducive to the operation, it also relaxes the muscles of the patient's eyelids and keeps the eyes open. . [0003] The common sense of daily life tells us that under normal conditions, the eyes will blink continuously, the frequency is about 15 times per minute, and the purpose is to keep the cornea moist. For patients ...

Claims

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Application Information

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IPC IPC(8): A61F13/02A61F9/00A61L15/00C08L33/02C08K13/02
Inventor 舒朝锋俞瑞珺
Owner HANGZHOU JUJIU SCI & BIOTECHNOLOGY CO
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