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Small and medium diameter artificial blood vessel with adjustable pressure and flow

An artificial blood vessel and adjustable technology, applied in the field of medical devices, can solve the problems of excessive size, lack of blood flow, and inability to effectively control shunt flow, and achieve good tissue compatibility and no rejection effect

Inactive Publication Date: 2014-05-28
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The reason why early preventive shunt surgery was not performed in time for liver cirrhosis portal hypertension, liver cancer portal hypertension, or small liver portal hypertension after liver transplantation is precisely because the shunt flow cannot be effectively controlled, so that the Postoperative complications caused by insufficient or excessive portosystemic shunt flow
[0008] Existing artificial blood vessels cannot be used for portosystemic shunt, precisely because of the long-term embolism and the lack of suitable for the autologous blood vessels, allogeneic blood vessels, synthetic material artificial blood vessels, tissue engineering blood vessels, etc. that have been clinically used. Performance issues in regulating its blood flow

Method used

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  • Small and medium diameter artificial blood vessel with adjustable pressure and flow
  • Small and medium diameter artificial blood vessel with adjustable pressure and flow
  • Small and medium diameter artificial blood vessel with adjustable pressure and flow

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0103] Example 1 Mechanical pressure flow control type artificial blood vessel

[0104] The mechanical pressure flow control type artificial blood vessel is composed of the artificial blood vessel 400 and the mechanical pressure flow control device ( figure 1 , Figure 2-10 ).

[0105] 1. Mechanical pressure flow regulator

[0106] The mechanical pressure flow regulator includes: a fixed shell 110 and a regulating spring 120 . A control port 117 is also provided on the fixed shell 110 ; the control spring 120 includes: a control spring wall ring 121 and a spring handle 123 . Such as figure 2 , image 3 and Figure 4 As shown, the position fixing hole 114 and the clasp 116 are used for assembling and fixing the regulating spring 120 and the artificial blood vessel 400 .

[0107] Control spring 120 ( Figure 4 ), consisting of two parts of spring handle 123 and regulating spring wall ring 121, in order to adjust the caliber of regulating and regulating spring wall ring ...

Embodiment 2

[0134] Example 2 In vitro remote control pressure flow control type artificial blood vessel

[0135] The extracorporeal remote-controlled pressure-flow regulating artificial blood vessel includes: the artificial blood vessel 400 and the extracorporeal remote-controlled pressure-flow regulator.

[0136] 1. In vitro remote control pressure flow regulator

[0137] In vitro remote pressure flow regulator ( Figure 11-Figure 24 ), including: a fixed shell 210, a control spring 220, a control axis 230 and an external remote controller 240. fixed shell ( Figure 11 , Figure 12 ), be provided with position fixing hole 214, position fixing hole 215 and clasp 216, in order to prepare for the in vivo position fixing after assembling and fixing regulating spring 220 and blood vessel anastomosis.

[0138] (1) fixed shell 210, such as Figure 11 , Figure 12 As shown, it is made of a rectangular sheet with hardness, foldability and elasticity, and is a short cylindrical fixed shell rin...

Embodiment 3

[0170] Example 3 In vivo induction pressure flow control type artificial blood vessel

[0171] The artificial blood vessel regulated by induction pressure and flow in the body includes: the artificial blood vessel 400 and the flow regulation by induction pressure in the body.

[0172] 1. Pressure flow regulation in the body

[0173] In vivo pressure-induced flow regulation ( Figure 25 , Figure 26 ), including: a fixed shell 310, a regulating spring 320, a regulating shaft core 330 and an inductor 340. The in vivo induction pressure and flow regulation of this embodiment is similar to the external remote control pressure and flow regulator of Embodiment 2, the difference lies in that an in vivo sensor 340 is installed in this embodiment.

[0174] (1) Fixed shell 310, regulating spring 320, regulating shaft core 330, such as Figure 25As shown, the two ends of the fixed shell 310 are respectively provided with position fixing holes 314 connected with the control spring 320...

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Abstract

The invention discloses a small and medium diameter artificial blood vessel with adjustable pressure and flow. The artificial blood vessel comprises a blood vessel wall, a blood vessel cavity is in the blood vessel wall, and a pressure and flow controller capable of adjusting the diameter of the artificial blood vessel is arranged outside the artificial blood vessel. Concave and convex grains are arranged on the blood vessel wall. The pressure and flow controller comprises a fixed shell and a control spring, wherein the fixed shell takes the shape of a cylindrical structure, and the control spring is configured to be a cylindrical structure, the control spring is arranged in the fixed shell and sleeved outside of the blood vessel wall of the artificial blood vessel, the control spring is provided with a limit spring handle for adjusting the diameter of the blood vessel, and the spring handle passes through a control frame. The fixed shell is provided with position fixing holes, and the control spring is provided with position fixing holes. The fixed shell is provided with a fastener. The pressure and flow controller comprises a mechanical pressure and flow controller, an in-vitro remote control pressure and flow controller and an in-vivo induction pressure and flow controller. The blood vessel is applicable to controlling the size of fractional flow according to an induced pressure of a hepatic portal vein after a portosystemic blood vessel is anastomosed and shunted so as to ensure the hepatic portal vein perfusion pressure required by individuals.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular, it is an artificial blood vessel with a small and medium-caliber adjustable pressure and flow rate. Background technique [0002] In the field of vascular surgery, large and medium-caliber artificial blood vessels have been widely used in clinics, and the effect of replacing arteries is remarkable. However, the long-term effects of small-caliber artificial vascular arteries (<6mm) and those used to replace veins are not satisfactory. In particular, there is still a lack of small and medium-caliber artificial blood vessels or replacement anastomotic tubes for special organs of the human body that need to regulate blood flow, so that corresponding diseases cannot be effectively treated or early curbed. For example, the anastomotic vessels currently used for portal hypertension shunt in liver cirrhosis, whether biological or artificial, cannot control the blood flow of the anastomot...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/06
Inventor 吴爱群杨广顺张卫周鹏张海斌张喜杨宁雷宇孙清清
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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