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32 results about "Hepatic portal vein" patented technology
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Vein in the portal venous system.
Hepatic portal vein tree modeling method and system thereof
InactiveCN101393644AEnhancement effect is goodEfficient removalImage enhancementImage analysisLiver parenchymaFiltration
The invention discloses a hepatic vein vascular tree modeling method and a system thereof. The method comprises the following steps: using a liver model to obtain a liver image, and utilizing the multi-scale filtration method to strengthen a blood vessel; cutting a hepatic vein; extracting a central line of the hepatic vein; detecting and removing a link in the central line; and utilizing OSG / VTK to rebuild the hepatic vein vascular tree after pruning. The system comprises an image acquisition module, a blood vessel strengthening module, a blood vessel cutting module, a vascular tree central line extracting module and a vascular tree rebuilding module. The invention improves similarity functions in the filtering process, analyzes the characteristics of the ring and adopts corresponding unlinking methods for different links; and utilizes the relation of radius of blood vessel and the branch length when pruning. The invention effectively enhances the hepatic vein, improves the contrast between the blood vessel and liver parenchyma, and can extract more than five class branches, effectively unlink and prune the central line of the hepatic vein, rebuild the hepatic vein vascular tree and directly display the branches of the heptatic vein.
Owner:HUAZHONG UNIV OF SCI & TECH
Method, system, apparatus, and computer program product for interactive hepatic vascular and biliary system assessment
A procedure for image segmentation on three-dimensional (3D) medical images, and a system, apparatus, and computer program that operate in accordance with the procedure. The procedure includes generating a projection including an anatomic structure, tracing a curve corresponding to the anatomic structure, extracting a curved volume of interest based on the curve and the projection, and extracting a segmentation of the anatomic structure. Also provided is a procedure for aligning anatomic structures in images, and a system, apparatus, and computer program that operate in accordance with the procedure. The procedure includes determining part of a biliary system in a first image, determining part of a hepatic portal vein or a hepatic artery in a second image, determining a gallbladder in the images, determining a cost function, and aligning the biliary system and the hepatic portal vein or hepatic artery by maximizing the cost function.
Owner:EDDA TECH
Treatment for renal failure
InactiveUS20140058372A1Ultrasound therapySpinal electrodesProphylactic treatmentContrast-induced nephropathy
A method of increasing renal function in a patient operates by stimulation of perivascular sympathetic nerves found in the vicinity of the hepatic portal vein and the hepatic artery. The method can be used as a treatment for renal failure or chronic kidney disease. Alternatively, the method can be used as a prophylactic treatment for preventing contrast-induced nephropathy or any other toxic nephropathy, which can result in renal failure. The perivascular sympathetic nerves can be stimulated by applying energy, such as electrical energy, light, vibration, and ultrasonic vibration, to the perivascular sympathetic nerves. Various methods are described for stimulating the perivascular sympathetic nerves using electrodes that are placed using minimally-invasive techniques.
Owner:SUPERRENAL
Method for isolating and culturing liver primary cells
InactiveCN102634480ALow pollution rateReduce pollutionArtificial cell constructsVertebrate cellsVitalityPrimary cell
The invention provides a method for isolating and culturing liver primary cells. The method comprises the following steps: (1) inputting perfusate from hepatic portal vein of a liver; (2) inputting collagenase perfusate; (3) soaking the maturely digested liver in the collagenase perfusate; (4) adding a cleaning solution to stop digestion, filtering, and collecting hepatic cell suspension; and (5) centrifuging, discarding supernatant, resuspending with complete medium, and culturing. The operation of the method provided by the invention is simple, is low in cost and is stable and efficient, and the hepatic cells are high in yield, high in vitality and easy for adherence. The method can be generalized in laboratories, and is a conventional method for scientific research.
Owner:CHINA AGRI UNIV
Noninvasive portal vein hemodynamic parameter measuring method
InactiveCN104107039ASimple and fast operationImprove accuracyBlood flow measurementVeinPortal vein flow
The invention provides a noninvasive portal vein hemodynamic parameter measuring method which includes the steps of firstly, using a thin-section CT image to build a three-dimensional geometric model of a liver portal vein; secondly, using the finite element analyzing method of hydromechanics calculating software ANSYS to perform meshing on the geometric model and build a three-dimensional mathematic model; thirdly, calculating the hemodynamic parameter of the portal vein in an analog manner to obtain a speed and pressure distribution effect picture. The method is safe, noninvasive, simple to operate, visualized, quantized and high in accuracy, and the effective model is built for scientific researches and clinic services.
Owner:SHANGHAI TONGJI HOSPITAL
Small and medium diameter artificial blood vessel with adjustable pressure and flow
The invention discloses a small and medium diameter artificial blood vessel with adjustable pressure and flow. The artificial blood vessel comprises a blood vessel wall, a blood vessel cavity is in the blood vessel wall, and a pressure and flow controller capable of adjusting the diameter of the artificial blood vessel is arranged outside the artificial blood vessel. Concave and convex grains are arranged on the blood vessel wall. The pressure and flow controller comprises a fixed shell and a control spring, wherein the fixed shell takes the shape of a cylindrical structure, and the control spring is configured to be a cylindrical structure, the control spring is arranged in the fixed shell and sleeved outside of the blood vessel wall of the artificial blood vessel, the control spring is provided with a limit spring handle for adjusting the diameter of the blood vessel, and the spring handle passes through a control frame. The fixed shell is provided with position fixing holes, and the control spring is provided with position fixing holes. The fixed shell is provided with a fastener. The pressure and flow controller comprises a mechanical pressure and flow controller, an in-vitro remote control pressure and flow controller and an in-vivo induction pressure and flow controller. The blood vessel is applicable to controlling the size of fractional flow according to an induced pressure of a hepatic portal vein after a portosystemic blood vessel is anastomosed and shunted so as to ensure the hepatic portal vein perfusion pressure required by individuals.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
Hepatic portal vein catheter
The invention discloses a hepatic portal vein catheter which comprises a catheter body, wherein a guide wire channel, a sensor groove and a lead groove are formed in the catheter body; a sensor whichis arranged in the sensor groove and used for measuring hepatic portal vein pressure; a lead which is arranged in the catheter body lead groove and is used for electrically connecting the sensor withexternal equipment of the catheter body; and coatings which are arranged on the outer surface of the wall surface of the catheter body and the sensing outer surface of the sensor and used for isolating direct contact between the catheter and external blood. The hepatic portal vein catheter integrates the pressure micro-sensor and the drug / electrical stimulation targeted treatment micro-channel atthe same time, hepatic portal vein pressure monitoring and targeted treatment can be carried out in a long-term implantation or short-term intervention mode, the sensor is directly integrated and packaged on the head of the catheter body, hepatic portal vein pressure can be directly measured, measurement feedback response is fast, accuracy is high, and popularization and application are easy. Meanwhile, the catheter is small in size, compact in structure and small in percutaneous puncture wound.
Owner:郑永昌 +2
Controlled-release composition for producing sustained-release preparation containing udenafil
This invention relates to a controlled-release composition for producing a sustained-release preparation containing udenafil, including (A) udenafil and a pharmaceutically acceptable salt, (B) a solubility modulator, (C) an adsorbent, and (D) a hydrophilic polymer. This controlled-release composition for producing a sustained-release preparation containing udenafil releases drugs constantly regardless of the pH level in the gastrointestinal tract, and thus freely controls the drug release time within the range of 3˜24 hours, and reduces the variability in the effect of drugs among individuals. Also, this composition can be produced into a sustained-release preparation which has an optimum condition for expressing the effect of drugs in the treatment of diseases including pulmonary arterial hypertension, hepatic portal vein hypertension, benign prostatic hyperplasia, and the like, which can be treated by udenafil and which requires the long-term drug administration. Also, this composition can control the release of drugs in accordance with the time taken for the absorption thereof when the drugs are applied to a living body, and thus can be valuably used in preventing and treating erectile dysfunction.
Owner:DONG A PHARMA
Small and medium diameter artificial blood vessel with adjustable pressure and flow
The invention discloses a small and medium diameter artificial blood vessel with adjustable pressure and flow. The artificial blood vessel comprises a blood vessel wall, a blood vessel cavity is in the blood vessel wall, and a pressure and flow controller capable of adjusting the diameter of the artificial blood vessel is arranged outside the artificial blood vessel. Concave and convex grains are arranged on the blood vessel wall. The pressure and flow controller comprises a fixed shell and a control spring, wherein the fixed shell takes the shape of a cylindrical structure, and the control spring is configured to be a cylindrical structure, the control spring is arranged in the fixed shell and sleeved outside of the blood vessel wall of the artificial blood vessel, the control spring is provided with a limit spring handle for adjusting the diameter of the blood vessel, and the spring handle passes through a control frame. The fixed shell is provided with position fixing holes, and the control spring is provided with position fixing holes. The fixed shell is provided with a fastener. The pressure and flow controller comprises a mechanical pressure and flow controller, an in-vitro remote control pressure and flow controller and an in-vivo induction pressure and flow controller. The blood vessel is applicable to controlling the size of fractional flow according to an induced pressure of a hepatic portal vein after a portosystemic blood vessel is anastomosed and shunted so as to ensure the hepatic portal vein perfusion pressure required by individuals.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
Oral suspension of liposome-encapsulated insulin lyophilized preparation and preparation process thereof
InactiveCN102144968BEasy to synthesizeMaintain a healthy weightPeptide/protein ingredientsMetabolism disorderOral suspensionsLiver functions
Owner:刘树森
Method for isolating and culturing primary liver cells
InactiveCN109161518ASimple preparation stepsHigh activityCell dissociation methodsVertebrate cellsBiologyCulture mediums
The invention belongs to the technical field of cell culture and particularly relates to a method for isolating and culturing a primary liver cell. The method comprises the following steps: preservingan isolated liver tissue in pre-cooled tissue storage fluid; taking out the liver tissue and inputting a perfusion solution from a hepatic portal vein of the liver tissue; after the completion of perfusion, putting the liver tissue in another container, then injecting a collagenase solution till a turtle-like fissure appears on the surface of the liver tissue, then dicing the liver tissue and soaking in the collagenase solution for 4-8 minutes to obtain a digested mature liver; cleaning the digested mature liver with double distilled water, filtering and collecting liver cell suspension; centrifuging the liver cell suspension, collecting a cell precipitate and performing resuspension culture with a culture medium to obtain the isolated primary liver cell. The method for isolating and culturing the primary liver cell, provided by the invention, has the benefits that a reagent formula of a traditional in-situ two-step perfusion method is simplified, the reagent preparation step is simplified, the cost is reduced, and the survival rate, the vitality and the purity of the isolated cell are improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV
Starch-indolic acid derivative, preparation method and application thereof
ActiveCN113912743AIncrease contentIncrease resistanceAntipyreticMetabolism disorderIntraperitoneal routeVenous blood
The invention provides a starch-indolic acid derivative, a preparation method and application thereof, and relates to the technical field of modified starch. According to the invention, the starch-indolic acid derivative is esterified starch generated by esterification reaction of starch and indolic acid under the action of a condensing agent and and alkali, has relatively high resistance, can resist degradation of the stomach and the small intestine, can release indolic acid beneficial to intestinal health through fermentation of intestinal flora after reaching the colon part, has obvious advantages compared with traditional administration modes such as intragastric administration, intraperitoneal injection and the like, and can obviously increase the content of indolic acid in colon and hepatic portal venous blood; and indoleic acid can activate an aromatic hydrocarbon receptor to play an immunoregulation role, and the indoleic acid and the regulation role of short-chain fatty acid released by fermentation of starch with intestinal flora are superposed, so that a product which synergistically plays the immunoregulation role through a plurality of immune system signal pathways is provided.
Owner:SHANDONG SHANWEI IMMUNOTECH CO LTD
Controlled-release composition for producing sustained-release preparation containing udenafil
InactiveCN102307597AFreely adjust the release timeLittle side effectsOrganic active ingredientsPill deliverySolubilityDisease
The present invention relates to a controlled-release composition for producing a sustained-release preparation containing udenafil. More particularly, the present invention relates to a controlled-release composition for producing a sustained-release preparation containing udenafil, said composition comprising (A) udenafil and a pharmaceutically acceptable salt, (B) a solubility modulator, (C) an adsorbent, and (D) a hydrophilic polymer. The controlled-release composition for producing a sustained-release preparation containing udenafil according to the present invention releases drugs constantly regardless of the pH level in the gastrointestinal tract, and thus freely controls the drug release time within the range of 3 to 24 hours, and reduces the variability in the effect of drugs among individuals. In addition, the composition of the present invention can be produced into a sustained-release preparation which has an optimum condition for expressing the effect of drugs in the treatment of diseases such as pulmonary arterial hypertension, hepatic portal vein hypertension, benign prostatic hyperplasia, and the like, which can be treated by udenafil and which requires the administration of drugs over a long period of time. Further, the composition of the present invention can control the release of drugs in accordance with the time taken for the absorption thereof when said drugs are applied to a living body, and thus can be valuably used in preventing and treating erectile dysfunction.
Owner:DONG A PHARMA
Method for isolating and culturing liver primary cells
InactiveCN102634480BLow pollution rateReduce pollutionVertebrate cellsArtificial cell constructsVitalityPrimary cell
The invention provides a method for isolating and culturing liver primary cells. The method comprises the following steps: (1) inputting perfusate from hepatic portal vein of a liver; (2) inputting collagenase perfusate; (3) soaking the maturely digested liver in the collagenase perfusate; (4) adding a cleaning solution to stop digestion, filtering, and collecting hepatic cell suspension; and (5) centrifuging, discarding supernatant, resuspending with complete medium, and culturing. The operation of the method provided by the invention is simple, is low in cost and is stable and efficient, and the hepatic cells are high in yield, high in vitality and easy for adherence. The method can be generalized in laboratories, and is a conventional method for scientific research.
Owner:CHINA AGRI UNIV
Application of ultrasonic detection equipment in semiquantitatively determining sheep fatty liver
InactiveCN106214184AUniversalGood repeatabilityOrgan movement/changes detectionInfrasonic diagnosticsIntestinal structureLiver and kidney
The invention belongs to the field of animal experimental models, and relates to application of ultrasonic detection equipment in semiquantitatively determining a sheep fatty liver. The application comprises the steps that a sheep fatty liver model is built by simulating negative balance of energy in the natural state; by means of characteristic analysis on liver ultrasonic images and corresponding data analysis on liver triglyceride content, a sheep fatty liver ultrasonic diagnosis method for semiquantitatively diagnosing that the liver triglyceride content is smaller than 4%, between 4% and 10% and larger than 10% is determined according to the liver echo brightness enhancing degree, the liver and kidney echo ratio increasing degree, the hepatic vessel visualization weakening degree and the acoustic shadow visualization fuzzy degree of hepatic portal veins, postcaval veins, rumen walls, intestines and diaphragms at the far field of the liver. The method is high in sensitivity, high in specificity and good in repeatability and has an ideal application prospect.
Owner:JILIN UNIV
In-vitro liver function detection method and system
ActiveCN111248869AEffective reflectionRespond quicklyDiagnostic recording/measuringSensorsBile JuiceVena porta
The invention relates to the technical field of medicine diagnosis and in particular relates to an in-vitro liver function detection method and system. The method comprises the following steps: a) respectively accessing arteries, veins and biliary tracts of a liver into related pipelines of an in-vitro liver mechanical perfusion apparatus, wherein the pipelines are filled with whole blood in advance; b) injecting a contrast medium into a hepatic portal vein to implement circulation, and testing T1 relaxation time of discharged bile by using a low-field magnetic resonance imaging analyzer; andc) comparing variation situations of the T1 relaxation time of the discharged bile with a reference value, and judging that if the T1 relaxation time of a same time point is longer than the referencevalue, it means that the metabolic function of the liver is lower that a liver corresponding to the reference value, and otherwise, it means the metabolic function of the liver is better than that ofthe liver corresponding to the reference value. The method makes up the limitation that liver functions cannot be directly reflected by conventional detection indexes.
Owner:GENERAL HOSPITAL OF SOUTHERN THEATRE COMMAND OF PLA +2
Semi-supervised learning-based portal vein detection and positioning method and system
PendingCN112733708AReduce the cost of manual labelingImage enhancementImage analysisVena portaEngineering
The invention provides a semi-supervised learning-based portal vein detection positioning method and system, and the method comprises the steps: carrying out model training through employing a semi-supervised learning model, carrying out feature extraction of unlabeled data, and taking the probability that whether a feature is a portal vein or not as a soft label; carrying out model training through a small number of label samples and a large number of label-free sample data, so that the manual labeling cost is greatly reduced; in addition, focus attention is formed through series connection of channel attention and space attention according to the position feature of the portal vein structure, so that priori knowledge is input into the convolutional neural network to guide model training, and the defects of existing portal vein detection are overcome; a loss function is replaced, a local loss function is selected as the loss function of the classifier, and normal training can still be carried out under the condition that positive and negative samples are unbalanced.
Owner:SHANDONG JIAOTONG UNIV
Liver segmentation system based on drainage basin analysis and operation method thereof
PendingCN113192604ARelieve painHelp determineMedical images3D modellingPattern recognitionVena porta
The liver segmentation system based on drainage basin analysis comprises a data receiving module, an image reading module, an image extraction module, an image processing module and an image analysis module; the image processing module comprises an image selection sub-module, an image editing sub-module and an image rendering sub-module, the image selection sub-module and the image editing sub-module carry out segmented processing on hepatic portal vein blood vessels, and the image rendering sub-module renders livers corresponding to the segmented hepatic portal vein blood vessels into different colors, thereby forming segments of the liver; and the image analysis module is used for carrying out segmented drainage basin analysis on the segmented liver. Compared with the prior art, accurate and personalized liver segmentation can be carried out according to portal vein space distribution condition characteristics of different patients, the segmentation result is accurate and objective, drainage basin analysis is carried out on the segmented liver, the liver segments with abnormal drainage basins are obtained, and determination and accurate implementation of a liver operation scheme are facilitated. Therefore, the operation time and cost can be saved, and pain of a patient is relieved.
Owner:杭州臻合健康科技有限公司
Teaching model for human body hepatic portal vein system anatomy and demonstrating method based on model
The invention discloses a teaching model for human body hepatic portal vein system anatomy and a demonstrating method of the human body hepatic portal vein system based on the model. The structure comprises a model box, an organ model and a vein system model are arranged in the model box, the organ model is composed of models of part of human organs, the vein system model is composed of vein models with the constitution being the same as that of the human body hepatic portal vein system, the vein models are hollow tubes made of a transparent material, LED lamp strips are arranged in the vein models in a penetrating manner, the LED lamp strips are connected to a power supply controller, and switch buttons used for controlling power supplies of the LED lamp strips are arranged on the power supply controller. According to the technical scheme, through the combination of sound, light and shape, the human body hepatic portal vein anatomy and blood circulation during the hepatic portal veinhypertension can be completely, accurately and intuitively displayed, so that a student can more easily understand the complicated anatomy structure, through practical teaching verification, the learning progress and understanding of the student for the relevant knowledge of the human body hepatic portal vein can be accelerated and deepened, in addition, the model device is integrally arranged inthe box, and thus teaching transfer is facilitated.
Owner:GUANGZHOU MEDICAL UNIV
In-vitro liver perfusion device
The invention discloses an in-vitro liver perfusion device which comprises a support, a clamping mechanism, a hepatic portal vein perfusion channel and a hepatic artery perfusion channel, wherein the clamping mechanism is arranged on the support and is used for clamping a ligament of the in-vitro liver so as to hang the in-vitro liver; the hepatic portal vein perfusion channel is slidably arranged on the support, and one end of the hepatic portal vein perfusion channel is communicated with a hepatic portal vein of the in-vitro liver; the hepatic artery perfusion channel is slidably arranged on the hepatic portal vein perfusion channel, and one end of the hepatic artery perfusion channel is communicated with the hepatic artery of the in-vitro liver. The ligament of the in-vitro liver is clamped through the clamping mechanism arranged on the support, so that the in-vitro liver is hung, the in-vitro liver is in a free sagging state, the whole in-vitro liver is not extruded, and the situation that the liver function is damaged due to stacking of the in-vitro liver when the in-vitro liver is directly contained in a container is prevented; and the hepatic portal vein perfusion channel and the hepatic artery perfusion channel are arranged, so that a perfusion tube can be conveniently inserted and is not easy to fall off, and perfusate can be prevented from leaking at the insertion part.
Owner:重庆北部宽仁医院
Liver subsection method based on CT image and system thereof
InactiveCN101425186BAvoid blurReduce noiseImage analysisComputerised tomographsPortal venous treeVena porta
The invention discloses a liver division method based on a CT image, which comprises the following steps: firstly, an MSCTP artery sequence image and a hepatic portal vein sequence image of the abdomen are pretreated, and the outline of the liver is automatically divided to obtain the liver image; secondly, a multi-scale filtering method based on a Hessian matrix is used for strengthening blood vessels, a dividing method such as region enlargement, and the like is used for dividing the hepatic portal vein, and a three-dimensional topology thinning method is used for picking up the central line of the hepatic portal vein; the blood vessels are identified mutually in classification; distance change and Voronoi arithmetic are then used for calculation, and the outline of the liver is used for covering values to obtain division results; the three-dimensional liver division results are finally reconstructed. The system comprises a liver division module, a blood vessel strengthening dividing and a thinning module, a blood vessel classifying module, a liver dividing module and a three-dimensional reconstructing module. The invention can reduce noise as well as avoid the vagueness of the boundary of the liver, effectively and exactly divides the outline of the liver, improves the division quality of the hepatic portal vein tree, and realizes accurate and rapid division of the liver.
Owner:HUAZHONG UNIV OF SCI & TECH
Method, system, apparatus, and computer program product for interactive hepatic vascular and biliary system assessment
A procedure for image segmentation on three-dimensional (3D) medical images, and a system, apparatus, and computer program that operate in accordance with the procedure. The procedure includes generating a projection including an anatomic structure, tracing a curve corresponding to the anatomic structure, extracting a curved volume of interest based on the curve and the projection, and extracting a segmentation of the anatomic structure. Also provided is a procedure for aligning anatomic structures in images, and a system, apparatus, and computer program that operate in accordance with the procedure. The procedure includes determining part of a biliary system in a first image, determining part of a hepatic portal vein or a hepatic artery in a second image, determining a gallbladder in the images, determining a cost function, and aligning the biliary system and the hepatic portal vein or hepatic artery by maximizing the cost function.
Owner:EDDA TECH
Breeding method for establishing primary biliary cholangitis model mouse through bile duct antigen immunity
The invention provides a method for cultivating a mouse model of primary biliary cholangitis, the method comprising: (1) perfusing the mouse liver with collagenase IV for 10 minutes through the hepatic portal vein, removing hepatic parenchymal cells, and obtaining Complete bile ducts; (2) shredding the bile ducts obtained in step (1), further using ultrasonic waves for homogenization, and quantifying the protein concentration of the obtained bile duct protein homogenate; (3) using the obtained bile duct proteins to The source mice were subcutaneously immunized to establish primary biliary cholangitis model mice induced by bile duct antigen immunization. The mouse obtained by the method of the invention can be used as a new animal model for screening drugs for primary biliary cholangitis.
Owner:UNIV OF SCI & TECH OF CHINA
Deep learning segmentation system for hepatic vein and hepatic portal vein
PendingCN114119538AImprove continuityImprove Segmentation AccuracyImage enhancementImage analysisHepatic veinsVena porta
The invention provides a deep learning segmentation system for hepatic veins and hepatic portal veins. The deep learning segmentation system comprises a coding module, a sequence attention association fusion module, an inter-slice-graph association module and a decoding module. An inter-slice-graph association module designed based on a graph neural network captures richer and higher-order relationships between adjacent CT sequences and improves the continuity of blood vessel segmentation; a sequence attention association fusion module designed based on an attention mechanism associates and fuses information of different dimensions, and the fine blood vessel segmentation accuracy is improved; in addition, the invention further provides a loss function combined with a blood vessel edge measurement constraint term, and the blood vessel edge is optimized and adjusted.
Owner:GUANGDONG UNIV OF TECH
A hepatic portal blood flow blocking device
ActiveCN108836420BAchieve expansion rather than shrinkingImplement injectionSurgeryVena portaShape-memory alloy
The invention discloses a hepatic portal blood flow blocking device, which relates to the field of clinical medicine, and comprises a catheter, a blocking bag and a positioning head. The base end of the catheter is provided with a protective plug to prevent external impurities from entering the catheter; At least one layer of flexible layer material, the inner surface of the flexible layer or in the flexible layer is provided with linear support frames arranged at intervals, and the support frames are made of shape memory alloy; the flexible layer surrounds the interior to form a cavity; the end of the cavity The positioning head is formed by a protrusion away from the catheter. The center of the positioning head is provided with a pinhole-shaped through hole connecting the outside to the cavity. The positioning head is also covered with an annular positioning ring. It realizes the ability to reduce the requirements for ultrasound-guided technology and puncture technology during use, and realizes simple and rapid blood flow occlusion in the hepatic portal vein, so as to implement precise resection. The technical effect of reducing the chance of portal vein metastasis and improving the survival rate of patients in the perioperative period after surgery.
Owner:李强
Method for collecting hepatic portal vein blood of machin
PendingCN114504399AAvoid damageEasy to operateSensorsBlood sampling devicesBlood collectionVena porta
The invention discloses a method for collecting hepatic portal vein blood of cynomolgus monkeys, and relates to the technical field of blood collection. Comprising the following steps: preoperative preparation work; cutting up and down along the middle abdominal line of the animal by taking the navel as a base point; after the abdominal cavity is exposed, the jejunum section of the animal is slightly pulled out of the abdominal cavity; a vein on the mesentery of the jejunum section is separated, the telecentric end is ligated, the proximal end is clamped by a vein clamp, and then a silk thread penetrates through the vein; a small opening is cut in the distal end of the vein, a catheter is inserted, after the catheter is inserted into the vein by 0.8-1.2 cm, a silk thread placed in advance is knotted, and the vein clamp is removed; the catheter is continuously inserted by 7-8 cm, and whether the catheter reaches the hepatic portal vein or not is detected by going deep into the abdominal hepatic portal vein with the hand; the catheter is fixed; resetting the ileum, leading the catheter out of the abdominal cavity, and closing the abdominal cavity; a small opening is formed in the abdominal wall on the right side, and the catheter is connected with the Port and buried subcutaneously.
Owner:苏州方达新药开发有限公司
Perfusion regulation
A system and method for cooperatively regulating the pressure and flow of an afferent vessel, such as both the hepatic portal vein and the hepatic artery. The present invention solves the problem of less-than-therapeutic portal flow during perfusion preservation by implementing cooperative regulation of inputs, such as the portal vein and hepatic artery pumping systems, on the organ preservation device. The system includes an algorithm adapted to the situation where the portal vein has reached minimum flow and maximum pressure. A cooperative regulation algorithm detects a problem with the portal vein and resolves it by adjusting the flow state of the hepatic artery.
Owner:LIFELINE SCI
Typing method based on intelligent hepatic portal vein
ActiveCN113096066AFast Smart TypingImprove formulation efficiencyImage enhancementImage analysisVena portaRadiology
A typing method based on an intelligent hepatic portal vein comprises the steps of establishing a digital liver three-dimensional model, analyzing the blood vessel shape, deformation, distribution and dominating areas of the hepatic portal vein, and automatically determining the type of the hepatic portal vein according to an analysis result, and specifically comprises the steps of establishing a hepatic portal vein digital model, performing three-dimensional reconstruction on the liver, finding the components of the hepatic portal vein in the component library of the three-dimensional model of the liver, and labeling the hepatic portal vein digitally. Compared with the prior art, the digital labeling is performed on the established three-dimensional model in advance, the personalized portal vein can be quickly and intelligently typed, the typing efficiency is improved, the occurrence probability of empirical errors is reduced, and the typing accuracy is improved. Based on the visual three-dimensional graph and portal vein typing, operation planning can be standardized, and the operation plan making efficiency is improved. By typing the hepatic portal vein, accidents in an operation can be effectively prevented, the operation risk is reduced, and the success rate of the operation is improved.
Owner:杭州臻合健康科技有限公司
Virtual hepatic vein pressure gradient measurement method
PendingCN112906323AIn line with real physiological conditionsAvoid or reduce the impactMedical simulationDesign optimisation/simulationBlood flowVena porta
The invention discloses a virtual hepatic vein pressure gradient measurement method, and belongs to the technical field of medicine. The method comprises the following steps: establishing a finite element calculation platform comprising a fluid mechanics calculation module, a solid mechanics calculation module and a fluid-solid coupling calculation module, importing an open geometric model for simulating liver vein free pressure, dividing grids of blood and a blood vessel wall, setting parameters, simulating fluid-solid coupling of the blood vessel wall and the blood, 0btaining pressure distribution and blood flow distribution of the simulated three-dimensional blood vessel model; obtaining a liver-portal vein model pressure distribution diagram and a virtual liver vein free pressure value; and obtaining the virtual hepatic vein wedging pressure, taking the difference value between the wedging pressure of the virtual hepatic vein and the free pressure of the virtual hepatic vein as the pressure gradient of the virtual hepatic vein. According to the method, a fluid-solid coupling model which better conforms to the real physiological condition of a human body is adopted, and the virtual hepatic vein pressure gradient measurement method with high accuracy is obtained.
Owner:LANZHOU UNIVERSITY
Noninvasive hepatic portal vein pressure estimation method and pressure measurement system
PendingCN114652352AAvoid bleeding riskMedical simulationMedical automated diagnosisVena portaDynamic models
Owner:CELL VALLEY (NANJING) BIOTECHNOLOGY CO
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