32 results about "Hepatic portal vein" patented technology

The invention relates to an oral suspension of a liposome-encapsulated insulin lyophilized preparation, named as O-SCULI. The O-SCULI contains lecithin, cholesterol, polyglycol aliphatic acid ester, vitamin E, insulin, water, sodium chloride and phosphate buffer. The invention also provides a two-step process of the O-SCULI, comprising (1) a dewatering / moistening control process: preparing a liposome-encapsulated insulin lyophilized preparation and SCLI so that the encapsulation rate of the insulin is increased to 80 percent by liposome amalgamation; and (2) a respective constant volume / stepped liquefaction process: preparing the SCLI into an O-SCULI oral suspension, preventing the SCLI liposome from leaking and keeping the constant encapsulation rate of the insulin. After a patient acutely takes the O-SCULI, the liposome insulin effectively enters the intestine-hepatic portal vein, the liver and the blood circulation to reduce blood sugar, blood fatty acids and blood ketone with highutilization degree. After a patient continuously orallly takes the oral suspension, the saccharification of hematoglobin, triglyceride and, aminotransferase and the oxidative stress are reduced, the structural damage of liver cells is recovered, and the comprehensive curative effects of diabetes treatment by using various liver functions are improved. The invention also opens up a new path for non-injection administration of active polypeptide protein, such as cytochrome C, albumin, interferon, and the like.

The invention discloses a liver division method based on a CT image, which comprises the following steps: firstly, an MSCTP artery sequence image and a hepatic portal vein sequence image of the abdomen are pretreated, and the outline of the liver is automatically divided to obtain the liver image; secondly, a multi-scale filtering method based on a Hessian matrix is used for strengthening blood vessels, a dividing method such as region enlargement, and the like is used for dividing the hepatic portal vein, and a three-dimensional topology thinning method is used for picking up the central line of the hepatic portal vein; the blood vessels are identified mutually in classification; distance change and Voronoi arithmetic are then used for calculation, and the outline of the liver is used for covering values to obtain division results; the three-dimensional liver division results are finally reconstructed. The system comprises a liver division module, a blood vessel strengthening dividing and a thinning module, a blood vessel classifying module, a liver dividing module and a three-dimensional reconstructing module. The invention can reduce noise as well as avoid the vagueness of the boundary of the liver, effectively and exactly divides the outline of the liver, improves the division quality of the hepatic portal vein tree, and realizes accurate and rapid division of the liver.

A procedure for image segmentation on three-dimensional (3D) medical images, and a system, apparatus, and computer program that operate in accordance with the procedure. The procedure includes generating a projection including an anatomic structure, tracing a curve corresponding to the anatomic structure, extracting a curved volume of interest based on the curve and the projection, and extracting a segmentation of the anatomic structure. Also provided is a procedure for aligning anatomic structures in images, and a system, apparatus, and computer program that operate in accordance with the procedure. The procedure includes determining part of a biliary system in a first image, determining part of a hepatic portal vein or a hepatic artery in a second image, determining a gallbladder in the images, determining a cost function, and aligning the biliary system and the hepatic portal vein or hepatic artery by maximizing the cost function.