Method for controlling environmental microorganism pollution with antibiotic-loaded bifunctional active nanofiber membrane

A technology of nanofiber membranes and environmental microorganisms, applied in botany equipment and methods, chemicals for biological control, biocides, etc., can solve the problems of easy loss and non-recyclable use, and achieve no secondary pollution, The effect of solving the risk of easy loss and reducing resistance

Inactive Publication Date: 2012-05-02
彭可扬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a chemical agent, antibiotics will not affect their antibacterial efficacy after immobilization, and solve the shortcomings of being unable to be recycled and easily lost

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Dissolve 1.3g of polylactic acid particles with a molecular weight of 100,000 and 0.2g of polyoxyethylene-polyoxypropylene-polyoxyethylene block copolymer in 10g of dichloromethane, mix evenly and stir until clear, and take 0.4g of kana Mymycin and 0.2 g of itraconazole were dissolved in 0.4 mL of deionized water. Stir vigorously to form an emulsion, and mix it with 2 mL of an aqueous solution containing 25% glutaraldehyde cross-linking agent, and the resulting precursor solution is ready to use under constant stirring.

[0023] The precursor solution is introduced into the electrospinning device to be spun. The electrospinning device consists of a high-voltage DC power supply (DW-P503-1ACF7, Dongwen, Tianjin), a peristaltic pump (BF300, Qili, Baoding), a plastic syringe, and 9# stainless steel. It consists of a needle and a Φ3mm polytetrafluoroethylene pipeline. Connect the negative electrode of the power supply to the filter screen of the air conditioner (Gree, KFR-2...

Embodiment 2

[0026] The same amount of F108 was used as the emulsifier to prepare the immobilized antibiotic active electrospun fiber membrane, and the Haier KFRd-23 air conditioner was treated with antibacterial treatment. The rest of the conditions were the same as in Example 1. No microorganisms could be detected after 15 days of cultivation.

Embodiment 3

[0028]The same amount of F127 was used as the emulsifier to prepare the immobilized antibiotic active electrospun fiber membrane, and the Haier KF-26GW air conditioner was treated with antibacterial treatment. The rest of the conditions were the same as in Example 1. No microorganisms could be detected after 15 days of cultivation.

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PUM

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Abstract

The invention relates to a method for controlling environmental microorganism pollution with an antibiotic-loaded bifunctional active nanofiber membrane. The method comprises the processes of: preparation of an electrospun fiber membrane and inhibition of microorganism breeding with the membrane, etc. Immobilized antibiotic active electrospun fiber membranes made by different emulsifiers are used for microorganism breeding inhibition on air conditioners of different specifications. And results show that, the method of the invention combines an electrospinning technology with an antibiotic combination technology, has a high efficiency bacteriostatic effect, and solves the disadvantages of non-recyclability and easy loss, etc. of antibiotics. By means of an in situ high-voltage electrospinning technology, the method of the invention can load an electrospun active fiber membrane on the surface and inside of indoor electrical appliances so as to realize functional protection to critical positions where pathogenic microorganisms are easy to breed and provide a long-acting, lasting and stable bacteriostatic and sterilizing ability.

Description

technical field [0001] The invention belongs to the technical field of environmental microorganism control, and in particular relates to a method for immobilizing various antibiotics for indoor microbial pollution prevention and control. Background technique [0002] The pollution degree of air microorganisms such as bacteria and fungi is one of the important parameters for evaluating indoor air quality. Indoor air microbial contamination can cause eye irritation, asthma, atopic dermatitis, hypersensitivity pneumonitis, and infectious diseases. Indoor building materials and household appliances are the main sources of indoor air pollution. They can not only release harmful chemicals to the human body, but also provide favorable conditions for the growth of microorganisms; develop practical indoor air antibacterial technology to inhibit building The growth of microorganisms such as materials, household appliances, household products, etc., to reduce the potential pollution s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N43/653A01N43/16A01N25/10A01P1/00A01P3/00D04H1/4326D04H1/435D04H1/728D01D5/00
Inventor 彭可扬
Owner 彭可扬
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