The invention discloses a compound emamectin benzoate and beta-cypermethrin pesticide composition, prepared from emamectin benzoate, beta-cypermethrin, spinosad, alpha-terpineol, matrine, nicotine, rotenone, santonin, stemonine and the like. The compound emamectin benzoate and beta-cypermethrin pesticide composition of the invention may also be prepared with a pharmaceutically-acceptable carrier into the preparations, such as emulsifiable concentrate, microemulsion, emulsion in water, suspension, wettable powder, water-dispersible granules, microcapsule suspension, suspension in oil, other granules and other powders, and is convenient to use and store; the pesticide ingredients having different acting mechanisms are compounded so that complementary and synergic effect is achieved; the compound emamectin benzoate and beta-cypermethrin pesticide composition has low toxicity but high efficiency, long acting period and little residue, is organic and environmentally friendly, rarely causesdrug resistance, allows reduced pesticide consumption, provides reduced cost of application and planting cost, allows relieved environmental pollution, is an environment-friendly pest-control pesticide composition and has a promising application prospect.