30results about How to "Reduced risk of developing resistance" patented technology

The invention discloses a c DNA (Complementary Desoxvribose Nucleic Acid) of a cotton bollworm COPI Beta gene and an application of the c DNA. A COPI Beta si (Small Interfering) RNA of a cotton bollworm is designed and synthesized, so that the expression of the COPI Beta gene is blocked after the COPI Beta si RNA is fed to the cotton bollworm, thus the death rate of the cotton bollworm is improved. Therefore, the biological prevention and control of the cotton bollworm is realized.

The invention discloses helicoverpa armigera V-ATPase A gene cDNA and application thereof. Helicoverpa armigera V-ATPase A siRNA is designed and synthesized, after helicoverpa armigera takes V-ATPase A siRNA in, expression of V-ATPase A gene is blocked, growth and metabolism of helicoverpa armigera are inhibited, the mortality is raised, and therefore helicoverpa armigera V-ATPase A gene cDNA is applicable to biological control of helicoverpa armigera.

The invention relates to a composition for controlling a diamondback moth of a brassicaceous vegetable and a preparation and application thereof. The composition contains two active components of chlorfenapyr(4-brombutyl-2-(4-chlorphenyl)-1-(ethoxymethyl)-5-(trichloromethyl)pyrrole-3-nitrile) and pyriproxyfen(4-phenoxylphenyl(RS)-2-(2-pyridyloxy)propyl ether), and the weight ratio of chlorfenapyr and pyriproxyfen is between 1:4 and 4:1. The composition preparation can be prepared from the composition with effective dosage, solid or liquid carriers, an auxiliary agent and other additives by a conventional method and used for processing the diamondback moth or a habitat thereof of the brassicaceous vegetable. The composition overcomes the defects of the prior art, expresses obvious synergy, can show optimal contact killing performance, stomach poisoning performance and ovicidal effect by processing the diamondback moth of the brassicaceous vegetable through applying smaller dosage, has long effect duration and simultaneously strengthens the rapid killing activity on the diamondback moth.

The invention discloses myzuspersicae hunchback gene cDNA and an application thereof; the cDNA of a key gene of hunchback (Mphb) for myzuspersicae embryonic development is transferred to a plant so as to obtain a transgenic plant which expresses Mphb dsRNA and inhibits myzuspersicae reproduction; when a myzuspersicae takes the transgenic tobacco, the expression of Mphb is inhibited; the embryonic development of the myzuspersicae is blocked; the daily mean myzuspersicae producing number is decreased; the reproductive capacity is reduced; and thus the myzuspersicae hunchback gene cDNA can be used for myzuspersicae biological control.

The invention discloses a bactericidal composition comprising probenazole and thifluzamide. The active ingredients of the bactericidal composition are probenazole and thifluzamide in a weight ratio of 1: 20 to 20: 1, and the active ingredients in the composition account for 5-60% by mass. The bactericidal composition disclosed by the invention is high in bactericidal activity, delays generation and development of drug resistance of pathogens, reduces the preventing and treating dosage in the actual production, and is economical, efficient, safe and environmental-friendly. The bactericidal composition disclosed by the invention has a good preventing and treating effect on various crop diseases, and particularly has a remarkable preventing and treating effect on rice sheath blight disease.

The invention relates to a method for controlling environmental microorganism pollution with an antibiotic-loaded bifunctional active nanofiber membrane. The method comprises the processes of: preparation of an electrospun fiber membrane and inhibition of microorganism breeding with the membrane, etc. Immobilized antibiotic active electrospun fiber membranes made by different emulsifiers are used for microorganism breeding inhibition on air conditioners of different specifications. And results show that, the method of the invention combines an electrospinning technology with an antibiotic combination technology, has a high efficiency bacteriostatic effect, and solves the disadvantages of non-recyclability and easy loss, etc. of antibiotics. By means of an in situ high-voltage electrospinning technology, the method of the invention can load an electrospun active fiber membrane on the surface and inside of indoor electrical appliances so as to realize functional protection to critical positions where pathogenic microorganisms are easy to breed and provide a long-acting, lasting and stable bacteriostatic and sterilizing ability.

The invention discloses myzuspersicae hunchback gene cDNA and an application thereof; the cDNA of a key gene of hunchback (Mphb) for myzuspersicae embryonic development is transferred to a plant so as to obtain a transgenic plant which expresses Mphb dsRNA and inhibits myzuspersicae reproduction; when a myzuspersicae takes the transgenic tobacco, the expression of Mphb is inhibited; the embryonic development of the myzuspersicae is blocked; the daily mean myzuspersicae producing number is decreased; the reproductive capacity is reduced; and thus the myzuspersicae hunchback gene cDNA can be used for myzuspersicae biological control.

The invention relates to a bactericidal composition comprising the effective components of kresoxim-methyl and tolclofos-methyl. The two effective components are compounded, which can expand the bactericidal spectrum, has synergistic interaction and reduces the application quantity. The bactericidal composition is suitable for preventing and treating soil-borne diseases on crops and is especiallysuitable for preventing and treating root rot.

The invention discloses a pesticide combination containing spinetoram and pyridaben, and belongs to the technical field of pesticides. The pesticide combination is prepared from the combination of the spinetoram, the pyridaben, fluorine silicon iodine, sodium humate, rh-5849, trifloxysulfuron sodium, ethrimol, coumaphos, 41% isopropylamine salt of N-glycine, benzenesulfonic acid emulsifying agents and benzene hydrocarbon. To obtain pesticide combination finished products, assistant agents of the pesticide combination containing the spinetoram and the pyridaben, dispersing agents, adjuvant, simethicone and water are needed, and the weight radio of the spinetoram to the pyridaben to the rh-5849 is 10: 4: 1. According to the pesticide combination, the two agents with totally different action mechanisms are blended, combined actions can be conducted on pests in many ways, and the purpose of effective control over the pests is achieved; meanwhile, the using dosage of the agents in field is reduced, the economic cost is saved, the pollution of the agents to the environment is reduced, and the risk that the pests develop resistance to the agents is also lowered.

The invention discloses a pesticide composition containing pyrazosulfuron-ethyl and difenoconazole and belongs to the technical field of pesticide. The pesticide composition is compounded and prepared from the following effective ingredients: abamectin, pyrazosulfuron-ethyl, fluorine silicon iodine, sodium humate, 1,2-dibenzoyl-1-tert-butylhydrazine, trifloxysulfuron sodium, ethirimol, coumaphos, merida, a benzenesulfonic acid emulsifier and a benzene solvent. When a finished product of the pesticide composition is prepared, following auxiliary agents of the pesticide composition containing the pyrazosulfuron-ethyl and the difenoconazole, a dispersing agent, an additive, simethicone and water are needed, and a weight ratio of the abamectin to the pyrazosulfuron-ethyl to the 1,2-dibenzoyl-1-tert-butylhydrazine is 10 to 4 to 1. According to the pesticide composition, the two kinds of pesticides with completely different action mechanisms are mixed to achieve combined action on pests from multiple aspects to achieve the purpose of effectively preventing the pests; meanwhile, a use amount of the pesticides in fields is reduced, economical cost is saved, pollution of the pesticides to environment is reduced, and risk that the pests generate resistance to the pesticides is also reduced.

The invention relates to the field of pesticide preparations, and provides a bactericide, in particular to a sterilizing composition. The sterilizing composition comprises the following active ingredients of nikkomycin and dioctyl divinyltriamino glycine according to the mass ratio of (1 to 30) to (3 to 1), wherein the total mass of the two components is equal to 2 to 60% of the composition. Compared with single agent, the bactericide has the advantages that the number of action mechanism and dots is more, the synergism function is obvious, the generation and development of drug resistance of pathogenic bacteria are effectively delayed, the absolute usage amount of pesticide is reduced, the cost is reduced, and the pollution to environment is reduced.

The invention discloses a bactericidal composition containing triclopyricarb and thifluzamide. The bactericidal composition consists of active components of triclopyricarb and thifluzamide in the mass ratio of 20:1-1:20, and the active components account for 5-60%. The bactericidal composition provided by the invention has high bactericidal activity, and delays the emergence and development of pathogen resistance, and reduces the dosage of prevention in actual production, and has the advantages of economical performance, high efficiency, safety and environment-friendliness. The bactericidal composition provided by the invention has good control effect on a variety of crop diseases, particularly significant control effect on rice sheath blight disease.

The invention relates to a method for preventing and controlling environmental microbial pollution by an antibiotic-loaded bifunctional active nanofiber membrane. The method includes the preparation of electrospun fiber membrane and the process of using it to inhibit the growth of microorganisms; using the immobilized antibiotic active electrospun fiber membrane prepared by different emulsifiers to inhibit the growth of microorganisms in air conditioners of different specifications, the results show that the The method combines the electrospinning technology and the combined use of antibiotics, which has a highly effective antibacterial effect, and solves the shortcomings of it cannot be recycled and easily lost. With the help of in-situ high-voltage electrospinning technology, electrospun active fiber membranes can be loaded on the surface and inside of indoor electrical appliances to achieve functional protection of key positions prone to pathogenic microorganisms, providing long-lasting, durable and stable Antibacterial and sterilizing ability.

Non-estrogen-dependent hyperproliferation of cells in animals or humans can be prevented or treated by means of a pharmaceutical or nutritional composition containing a combination of at least three components from: a) two or more inhibitors of the G1 / S phase of the cell cycle; and b) two or more inhibitors of the G2 / M phase of the cell cycle; and c) two or more inhibitors of protein tyrosine kinase activity. Especially, component a) comprises two or more compounds selected from flavanolignans, carotenoids and isoflavone; component b) comprises two or more compounds selected from flavanolignans, hydroxylated stilbenes, isoflavones and apigenin; and component c) comprises two or more compounds selected from flavanolignans and isoflavones.

The invention relates to a composition of pyriproxyfen and nitenpyram. The composition contains two active components of the pyriproxyfen and the nitenpyram, and the pyriproxyfen and the nitenpyram are blended with a solid or liquid carrier and auxiliary agents to prepare a composition preparation thereof for controlling rice planthoppers. The composition of the pyriproxyfen and the nitenpyram has obvious synergistic activity, and the compounding of the pyriproxyfen and the nitenpyram can furthest perform respective drug effects, reduce the occurrences of resistance risk of the rice planthoppers, reduce the dosage and save the cost.

The invention discloses a c DNA (Complementary Desoxvribose Nucleic Acid) of a cotton bollworm COPI Beta gene and an application of the c DNA. A COPI Beta si (Small Interfering) RNA of a cotton bollworm is designed and synthesized, so that the expression of the COPI Beta gene is blocked after the COPI Beta si RNA is fed to the cotton bollworm, thus the death rate of the cotton bollworm is improved. Therefore, the biological prevention and control of the cotton bollworm is realized.

The invention discloses an insecticidal composition containing effective components of HNPC-A8008, chemically named as (E)-5-(3-chloroallyl)amino-1-(2,6-dichloro-4-trifluoromethyl)phenyl-4-trifluoromethyl sulfinyl pyrazol-3-nitrile, and metaflumizone. The weight ratio of the HNPC-A8008 to the metaflumizone is (1 to 100)-(100 to 1); the mass fraction percentage of the HNPC-A8008 and the metaflumizone is 10%-60% of the total mass of the insecticidal composition. Finished preparations of the insecticidal composition comprise missible oil or a microemulsion, a water emulsion, a suspending agent, wettable powder and a water dispersible granule. According to the insecticidal composition, the resistance risk of pests to medicaments is reduced; meanwhile, the limitations that a single component is relatively narrow in prevention and control spectrum and slowly acts or is short in lasting period are overcome, and the multiple kinds of pests can be simultaneously prevented and controlled by applying the insecticidal composition once; furthermore, the insecticidal composition maintains the advantage that the metaflumizone is long in lasting period, further has the advantage that the HNPC-A8008 is high in knockdown speed and is capable of preventing and controlling lepidoptera pests of crops such as vegetables, cotton, fruit trees and flowers; 1g-5g of the insecticidal composition is consumed in each mu (unit of area) of field; the insecticidal composition is an excellent substitute variety of high-toxicity pesticides.

The invention discloses a bactericidal composition containing thiabendazole and thiabendazole, the active components of the bactericide composition are thiabendazole and thiabendazole, and the mass ratio of thiabendazole and thiabendazole is 1 : 20 to 20:1, the mass percentage of active components in the composition is 5-60%. The bactericide composition of the present invention has high bactericidal activity, delays the generation and development of drug resistance of pathogens at the same time, and reduces the amount of control medication in actual production, and is economical, efficient, safe and environmentally friendly. The invention has good control effects on various crop diseases, and the control effect on rice sheath blight is particularly remarkable.

The invention provides a sterilization composition and a use thereof. The main active components of the sterilization composition comprise a first component thiatrifloxystrobin and a second componentwhich is triflumizole, prothioconazole, isopyrazam or ethylicin, wherein a mass ratio of the first component to the second component is 1:30 to 30:1, and the total mass of the two components is 5-60%of the total mass of the sterilization composition. The composition has a low toxicity, has small harms to human, animals and the ecological environment, can delay the occurrence and development of the pathogenic drug resistance, has a good control effect on ring spot, black spot, brown spot, powdery mildew and other fungal diseases, and has a broad application prospect.

A kind of E78-C gene cDNA of cotton bollworm ecdysone regulatory factor, clones the ecdysone-inducible factor E78-C gene from cotton bollworm, and designs primers for the ecdysone-induced factor E78-C gene of cotton bollworm, selects SEQ ID NO. The 658-1122 position in 1 was used as the E78-C target gene fragment to synthesize dsRNA, and then the synthesized dsRNA was delivered to the body cavity of cotton bollworm by microinjection, and the green fluorescent protein (GFP) was used as the control group, and the dsRNA after injection was counted. The amount of eggs laid by cotton bollworm shows that the E78-C gene of cotton bollworm is used as the target gene for interference, and the injection interference is performed on the cotton bollworm to silence the transcription and expression of the gene, thereby inhibiting the development of the ovary of the cotton bollworm, reducing the amount of eggs laid, and then controlling its population; and The risk of pest resistance is low, which provides a theoretical basis for the creation of new biopesticides and plant insect-resistant genetic engineering.

Prophylaxis and treatment of estrogen-independent hyperproliferation of cells in animals or humans by means of a pharmaceutical or nutritional composition comprising a) two or more inhibitors of the G1 / S phase of the cell cycle and b) two or more inhibitors of the G2 / M phase of the cell cycle; and c) at least three components of the two or more protein tyrosine kinase inhibitors. In particular, component a) includes two or more compounds selected from flavonoids, carotenoids, and isoflavones; component b) includes compounds selected from flavonoids, hydroxylated stilbenes, isogenistein, and celery Two or more compounds of aglycone; component c) includes two or more compounds selected from flavonoids and isoflavones.

The invention discloses a bacterial composition containing oxalate diacetonamine copper and a benzimidazole bactericide. The bacterial composition comprises a first active ingredient and a second active ingredient. Weight ratio of the first active ingredient to the second active ingredient is 1:15-15:1. The first active ingredient is oxalate diacetonamine copper. The second active ingredient is one ingredient selected from thiophanate methyl, carbendazim, benomyl and thiabendazole. The composition can be made up into water dispersible granules, a wettable powder, a suspending agent or a dispersible oil suspension which is allowed for use in agriculture, and has a good effect of controlling powdery mildew of cucumber, cucumber downy mildew, botrytis cinerea, tomato early blight, apple altermaria leaf spot, apple brown spot, apple mildew or potato late blight. By the use of the bacterial composition, the problem that oxalate diacetonamine copper or the above benzimidazole bactericide has non-ideal control effects when separately used is solved effectively. By two-component compounding, the bacterial composition has remarkable synergism and has good safety for crops, and resistance risks and drug delivery costs are reduced.

The invention relates to a composition for controlling a diamondback moth of a brassicaceous vegetable and a preparation and application thereof. The composition contains two active components of chlorfenapyr(4-brombutyl-2-(4-chlorphenyl)-1-(ethoxymethyl)-5-(trichloromethyl)pyrrole-3-nitrile) and pyriproxyfen(4-phenoxylphenyl(RS)-2-(2-pyridyloxy)propyl ether), and the weight ratio of chlorfenapyrand pyriproxyfen is between 1:4 and 4:1. The composition preparation can be prepared from the composition with effective dosage, solid or liquid carriers, an auxiliary agent and other additives by a conventional method and used for processing the diamondback moth or a habitat thereof of the brassicaceous vegetable. The composition overcomes the defects of the prior art, expresses obvious synergy,can show optimal contact killing performance, stomach poisoning performance and ovicidal effect by processing the diamondback moth of the brassicaceous vegetable through applying smaller dosage, has long effect duration and simultaneously strengthens the rapid killing activity on the diamondback moth.

The invention provides a paddy field herbicide composition which comprises the following active ingredients: mesotrione A, a cyclic imide herbicide B and a paddy field herbicide C, wherein the cyclic imide herbicide B is selected from oxadiazon, oxadiargyl or pentoxaxone, and the paddy field herbicide C is selected from bensulfuron methyl, halosulfuron methyl, pyriftalid, pretilachlor, butachlor, mefenacet, penoxsulam, prometryn or simetryn. The paddy field herbicide composition is used for preventing and controlling annual and perennial weeds in paddy fields. The composition has an obvious synergistic or additive effect for controlling weeds in the paddy fields in a certain matching range, and the effect of preventing and controlling annual weeds in the paddy fields is obviously better than that of each single dose. The weed removing spectrum is expanded, the dosage is reduced, the herbicide cost is reduced, and the adverse effect of pesticides on the ecological environment is reduced.

The invention provides a bactericide, and particularly provides an agriculturally bactericidal composition. The composition comprises two components: 2-cyano-3-phenyl-3-aminoethyl acrylate and ethylicin, wherein the mass ratio of the components I to the component II is (1:5)-(30:1), and the total mass of the two components takes up 5%-80% of that of the composition. The composition is low in toxicity, slight in damage to people and livestock and ecological environment, and capable of delaying the generation and development of pathogen drug resistance, and has high prevention and treatment effects on the crop disease caused by fusarium, especially on wheat fungoid disease. The bactericidal composition has wide application prospects.

The invention discloses a compound containing the chemical name (E)-5-(3-chloroallyl)amino-1-(2,6-dichloro-4-trifluoromethyl)phenyl-4-trifluoro The insecticidal composition of HNPC-A8008 and metaflumizone active ingredients of methylsulfinylpyrazole-3-nitrile, the weight ratio of HNPC-A8008 and metaflumizone in the composition is 1:100~100: 1. The total mass percentage of HNPC‑A8008 and metaflumizone in the composition is 10% to 60%. The finished preparations of the composition include emulsifiable concentrates or microemulsions, aqueous emulsions, suspensions, wettable powders, and water-dispersible granules. The invention reduces the dosage of the medicament and reduces the risk of pest resistance to the medicament. At the same time, it overcomes the limitations of narrow control spectrum and slow action or short duration of single component. It can control multiple pests that occur at the same time with one application, and maintains the advantages of long duration of metaflumizone. With the advantage of fast knockdown speed of HNPC‑A8008, it can effectively control Lepidoptera pests in crops such as vegetables, cotton, fruit trees and flowers. The dosage per mu is 1-5g, and it is an excellent substitute for highly toxic pesticides.

The invention relates to a herbicide composition, and especially relates to a herbicide composition used for controlling paddy field weed, wherein amides, clomazone, and (E)-pyriminobac-methyl are taken as the active components of the herbicide composition at a preferable weight ratio of (15-66): (1-7): (0.5-3), and the amount of the active components in the herbicide composition ranges from 22.5 to 85% preferably. The combination of the herbicide composition is reasonable; weed control spectrum is widened; controlling effect on worst weed is improved; the using amount of single-component herbicide is reduced; herbicide application times are reduced; intervals are prolonged; prevention cost is reduced; generation of drug resistance of weed on the three active components is delayed; the herbicide is safe for paddy rice, and is an ideal herbicide.

Cotton bollworm E75 gene, select the target fragment containing SEQ ID NO: 3, and then synthesize dsRNA, and then introduce the synthesized dsRNA into the 5th instar larva of cotton bollworm by microinjection, and express after the synthetic dsRNA is injected into the E75 gene of cotton bollworm Inhibited, the molting metamorphosis process of the cotton bollworm is destroyed, effectively reducing the pupation rate of the cotton bollworm, and then controlling its population; the research foundation is good, the prospect is high, and the risk of pest resistance is low, which is an important step for the creation of new biological insecticides. Provide a theoretical basis for pesticides and plant insect-resistant genetic engineering.

The invention discloses a sterilization composition containing epoxiconazole and thiabendazole and an application thereof. The active components of the sterilization composition are epoxiconazole and thiabendazole, the mass ratio of epoxiconazole to thiabendazole is (1:20) to (20:1), and the content of the active components in the composition is 5-60% in percentage by mass. The sterilization composition disclosed by the invention has high sterilization activity, is capable of delaying the generation and development of pathogens resistance to xenobiotics and reducing prevention and treatment dosages in practical production, and is economical, efficient, safe and environment-friendly. The sterilization composition disclosed by the invention has good prevention and treatment effects on various crop diseases, and has especially remarkable prevention and treatment effects on rice sheath blight disease.