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Freckle-removing liquid as well as preparation method and application thereof

A technology of freckle removal and aqueous solution, which is applied in the field of medical cosmetic compositions, can solve problems such as scars, pigmentation, and depigmentation, and achieve the effect of convenient use and remarkable therapeutic effect

Inactive Publication Date: 2012-05-02
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because chemical drugs are often corrosive, improper use is likely to cause long-term pigmentation or depigmentation, and even scars, disfigurement, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1 Preparation of freckle-removing liquid

[0024] Take 100g of the traditional Chinese medicine Brucea javanica after peeling, treat it with a microwave radiation power of 300 W and a radiation time of 5.5 minutes until it turns slightly yellow, grind it, pass through a 40-mesh sieve, add 90% ethanol to soak the medicinal material for 24 hours, and mix the crude material of Brucea javanica with 90% ethanol The mass ratio is 1:5, and then the microwave power is 300W, and the radiation time is 7min, so that the temperature of 90% ethanol is raised to 60°C, and ultrasonically extracted at this temperature for 3 hours, and the solvent is recovered by a constant temperature rotator to obtain the extract of Brucea javanica alcohol. Material 12.6g.

[0025] Take the dried podophyllum root and crush it into 50g of coarse powder, pass through a 20-mesh sieve, add 90% ethanol to soak the medicinal material for 24 hours, the mass ratio of podophyllum crude material to 90% ...

Embodiment 2

[0028] Example 2 Clinical Experiment of Freckle-removing Liquid

[0029] Put 5ml of the spot-removing liquid prepared in Example 1 into the tube of an aluminum beauty pen, install the front pressure straight liquid valve, put on the nib and nib, cover the cap, and then make the medical beauty spotting pen.

[0030] The medical cosmetic spotting pen was clinically applied to 156 cases of photoaging facial pigment spots, senile plaques, solar keratosis, freckles, and freckle-like nevus. The patients held the pen by themselves to apply targeted spots on the spots, and observed them until frosty white After 30 minutes, the skin lesions turned into dark brown scabs. About 7 days later, the scabs fell off and the spots were removed. 96.7% of the patients were cured after one treatment, and 7% of the patients had temporary pigmentation. It subsided within 1 to 6 months, and no adverse reactions such as persistent pigmentation, persistent erythema, and scars were found. Follow-up for...

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PUM

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Abstract

The invention discloses a freckle-removing liquid as well as a preparation method and application thereof. The freckle-removing liquid mainly comprises the following components in parts by weight: 2-20 parts of kosam seed alcohol extract, 1-5 parts of maypop extract, 10-20 parts of glycerol, 5-10 parts of camphor and 45-82 parts of phenol water solution with mass percentage concentration more than 80%. The preparation method of the freckle-removing liquid comprises the steps of: firstly crushing kosam seed kernel and maypop, soaking with ethanol overnight, ultrasonically extracting, mixing and grinding glycerol and camphor to obtain a mixture, adding dissolved phenol, slowly adding kosam seed alcohol extract, finally adding maypop alcohol extract, uniformly mixing and standing to obtain the freckle-removing liquid. The obtained freckle-removing liquid has good treatment effect on color spot caused by light aging, senile plaque, solar keratosis, pigmentation after acne, freckle and / or freckle-like nevus, and has safety in use, no side effect and wide application prospects.

Description

technical field [0001] The invention relates to the technical field of medical cosmetic compositions, in particular to a spot-removing liquid and a preparation method thereof. Background technique [0002] The treatment and prevention of facial pigmentation has always been a difficult problem in the medical field. In particular, the incidence of photoaging skin hyperpigmentation spots, age spots, solar keratosis, post-acne hyperpigmentation spots, freckles, and freckles is very high for those over 30 years old. For example, senile plaques can start to appear at the age of 30. The incidence rate of the elderly over the age of 60 is 80%, and that of the elderly over the age of 80 is 100%. Symptoms, causing patients to scratch, rub, and scabs can be infected and even cancerous after irritation; according to a multi-center survey, the incidence rates of men and women over 40 years old are 15.4% and 5.9%, respectively, and As the age increases, the incidence rate increases furt...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/29A61P17/00A61K31/047A61K31/125
Inventor 王红丽关向东单孔荣程靖
Owner GUANGDONG PHARMA UNIV
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