Shenkang sodium chloride injection for treating chronic renal failure and preparation method of Shenkang sodium chloride injection
A Shenkang sodium chloride and chronic renal failure technology, applied in the field of traditional Chinese medicine injections, can solve the problems of no ratio relationship, affecting drug efficacy, and high usage of astragalus, achieving rapid action, short course of treatment, and high bioavailability Effect
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Embodiment 1
[0109] The Shenkang sodium chloride injection of the present invention is made of the following raw materials: 1500g of rhubarb, 1500g of salvia miltiorrhiza, 4500g of astragalus, 1500g of safflower and 810g of sodium chloride.
[0110] After extracting the raw materials rhubarb and salvia miltiorrhiza according to the proportion of the above formula, first alcohol precipitation, detanning, second alcohol precipitation, water precipitation, third alcohol precipitation, and second water precipitation, depyrogenation and sterilization; Extract astragalus and safflower according to the proportion of the above formula, alcohol precipitation, water precipitation, alcohol precipitation and water precipitation again, activated carbon depyrogenation, and sterilization; finally combine the above two groups of dilutions, ultrafiltration, It is made by adding sodium chloride, fine filtration→subpackaging→sterilization→quality inspection→packaging.
Embodiment 2
[0112]Shenkang sodium chloride injection of the present invention is made according to the following preparation method: get rhubarb and salvia miltiorrhiza, the amount of water added for the first time is 7-12 times the amount of the original medicinal material, after soaking for 30 minutes, boil for 30 minutes, filter, and the second time The amount of water added for the first time is 7-12 times the amount of the original medicinal material, boiled for 30 minutes, filtered, the amount of water added for the third time is 7-12 times the amount of the original medicinal material, boiled for 30 minutes, filtered, combined three water extracts, concentrated to relative density 1.18-1.25 at 60°C, add 95% ethanol until the alcohol content of the liquid is 70%, let stand for 38-60h, take the supernatant and filter until clear, recover ethanol until the relative density is 1.18-1.25 at 60°C, add 5% gelatin solution, remove tanning, add 95% ethanol until the alcohol content is 75%, l...
Embodiment 3
[0114] The preparation method of Shenkang sodium chloride injection of the present invention is: after selecting 1500 g of rhubarb, 1500 g of salvia miltiorrhiza, 4500 g of astragalus and 1500 g of safflower, cleaning, soaking, cutting and drying; weighing 1500 g of rhubarb and 1500 g of salvia miltiorrhiza For medicinal materials, the amount of water added for the first time is 10 times the amount of the original medicinal materials, soaked for 30 minutes, boiled for 30 minutes, filtered, the amount of water added for the second time is 8 times the amount of the original medicinal materials, boiled for 30 minutes, filtered, and the amount of water added for the third time is 7 times the amount of the original medicinal material, boil for 30 minutes, filter, combine three water extracts, concentrate to a relative density of 1.20-1.22 at 60°C, add 95% ethanol, until the alcohol content of the liquid is 70%, let it stand for 48-60h , take the supernatant and filter until clear, r...
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