Preparation method of artificial bone support with controllable porosity

A technology of artificial bone and porosity, applied in bone implants, etc., can solve the problems of uncontrollable porosity and difficulty in meeting the bone needs of different parts of patients with individual differences, so as to achieve accurate, effective and controllable porosity and reduce contamination Chance, avoidance cost and time effects
CN102499794AActive Publication Date: 2012-06-20西安博恩生物科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
西安博恩生物科技有限公司
Publication Date
2012-06-20

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Abstract

The invention discloses a preparation method of an artificial bone support with controllable porosity, which comprises the following steps of: establishing a CAD (Computer-Aided Design) model according to the individual characteristics of patients; introducing the model into a three-dimensional printer; analyzing a particle flow software number value computing result according to a disperse number value; and mixing biological ceramic small balls and biological instantly-dissolved small balls according to a certain proportion; and spraying biological adhesive through the three-dimensional printer to adhere the mixed balls so as to prepare the artificial bone support. In order to overcome the defect that in the prior art, during the preparation process, sintering can cause pollution, in the invention, the porosity is obtained by instantly dissolving the instantly-dissolved small balls into the biological dissolved solution, so that the pollution of the sintering and chemical reaction during the preparation process on the artificial bone support can be avoided, and in addition, by controlling the number and the radius of the instantly-dissolved small balls, the biological ceramic artificial bone support with a certain mechanical property and porosity can be obtained.
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Description

[0001] Field:

[0002] The invention relates to a method for preparing an artificial bone scaffold based on porous bioceramic microspheres. It involves using discrete numerical simulation and particle flow numerical simulation as calculation theories to obtain active bioceramic microsphere artificial bone scaffolds with different porosity by controlling the number and radius of instant biospheres. Background technique:

[0003] Human bones have a certain ability to regenerate and self-repair, but for large bone defects caused by trauma, infection, tumors and developmental deformities, relying solely on the self-repair function of bone organs cannot heal, and bone transplantation is required. The transplant materials mainly include autologous bone, allogeneic bone and artificial bone replacement. The effect of autologous bone tissue transplantation is very good, and there is no immune rejection reaction, but the source is limited, secondary surgery is required, and there are of...

Claims

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