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Traditional Chinese medicine combination for clearing heat and calming livers and preparation method thereof

A technology of composition and traditional Chinese medicine, applied in the direction of drug combination, medical formula, drug delivery, etc., can solve problems such as decompensation of blood pressure regulation mechanism, and achieve significant economic and social benefits, improved curative effect, and excellent blood pressure lowering effect

Active Publication Date: 2014-06-18
LONGSHUNRONG PHARMA FACTORY TIANJIN ZHONGXIN PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the cause of hypertension has not been elucidated so far. It is generally believed that it is caused by the decompensation of normal blood pressure regulation mechanism due to the participation of various environmental factors in a certain genetic background.

Method used

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  • Traditional Chinese medicine combination for clearing heat and calming livers and preparation method thereof
  • Traditional Chinese medicine combination for clearing heat and calming livers and preparation method thereof
  • Traditional Chinese medicine combination for clearing heat and calming livers and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1: preparation of Chinese medicine extract

[0024] 1. Prescription: Scutellaria baicalensis 1130g Huaijiao 1130g Arachis branches and leaves 1130g Benzylamine hydrochloride 10g Hydrochlorothiazide 15g

[0025] Two. Preparation method:

[0026] Weigh each raw material according to the ratio of raw materials, and set aside; Scutellaria baicalensis is extracted twice with 70% ethanol with 8 times the volume percentage, each time for 2 hours, and the alcohol extract is combined, concentrated to a relative density of 1.05 under the condition of 50-60°C , to obtain concentrated solution A for subsequent use; Sophora japonica and groundnut branches and leaves were extracted twice with 8 times the amount of water, each time for 2 hours, the water extracts were combined, concentrated to a relative density of 1.05 under the condition of 50-60 ° C, and concentrated solution B was obtained; The concentrates A and B are dried and mixed to obtain a dry product I; the ben...

Embodiment 2

[0028] Embodiment 2: preparation of Chinese medicine extract

[0029] 1. Prescription: Scutellaria baicalensis 1130g Huaijiao 1130g Arachis branches and leaves 1130g Benzylamine hydrochloride 10g Hydrochlorothiazide 15g

[0030] Two. Preparation method:

[0031] Weigh each raw material according to the ratio of raw materials and set aside; Scutellaria baicalensis is extracted with ethanol twice, first add 8 times the amount of 60% ethanol to extract for 2 hours, add 6 times the amount of 60% ethanol for the second time to extract for 1.5 hours, and combine the ethanol extracts , concentrated to a relative density of 1.05 under the condition of 50-60°C, and the concentrated solution A was obtained for use; the branches and leaves of Huaijiao and groundnut were extracted twice with 8 times the amount of water, each time for 2 hours, and the water extracts were combined and concentrated to 50-60°C Under the conditions, the relative density is 1.08, and the concentrated solution ...

Embodiment 3

[0033] Embodiment 3: preparation of Chinese medicine extract

[0034] 1. Prescription: Scutellaria baicalensis 113g Huaijiao 113g Arachis branches and leaves 113g Benzylamine hydrochloride 1g Hydrochlorothiazide 15g

[0035] Two. Preparation method:

[0036] Weigh each raw material according to the ratio of raw materials and set aside; Scutellaria baicalensis is extracted with ethanol twice, first add 8 times the amount of 70% ethanol to extract for 2 hours, add 8 times the amount of 70% ethanol for the second time to extract for 1.5 hours, and combine the ethanol extracts , concentrated to a relative density of 1.05 under the condition of 50-60°C, and the concentrated solution A was obtained for later use; the branches and leaves of Sophora japonica and Arachis were extracted with water twice, the first time was extracted with 10 times the amount of water for 2 hours, and the second time was added with 8 times the amount of water Extract for 1.5 hours, combine the water extr...

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Abstract

The invention discloses a traditional Chinese medicine combination for clearing heat and calming livers and a preparation method thereof, which belong to the field of traditional Chinese medicine modernization. The active constitutions of the traditional Chinese medicine combination for clearing heat and calming livers are composed of the following medicines by parts of weight: 1130 parts of scutellaria baicalnesis, 1130 parts of sophora fruit, 1130 parts of peanut branch leaf, 10 parts of hydrochloric acid methyl allylene benzylamine and 15 parts of hydrochlorothiazide. The traditional Chinese medicine combination has the advantages of being stable and controllable in quality, remarkably high in curative effect compared with existing drugs sold in markets, and obvious in economic and social benefits.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for clearing heat and calming the liver and a preparation method thereof, belonging to the field of traditional Chinese medicine modernization. Background technique [0002] Hypertension is a worldwide common disease. The prevalence rate in various countries is as high as 10% to 20%, and it can lead to cerebrovascular, heart, and kidney lesions. It is a major disease that endangers human health. However, the cause of hypertension has not been elucidated so far. It is generally believed that it is caused by the decompensation of normal blood pressure regulation mechanism due to the participation of various environmental factors in a certain genetic background. Most of them are asymptomatic in the early stage, and occasionally high blood pressure is found during physical examination, or dizziness, headache, vertigo, tinnitus, insomnia, fatigue, inattention and other symptoms after mental...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/539A61K9/00A61K9/20A61K9/48A61P9/12A61K31/137A61K31/549
Inventor 潘勤王欣聂万达闫晓楠朱晓丹游强蓁
Owner LONGSHUNRONG PHARMA FACTORY TIANJIN ZHONGXIN PHARMA GRP