Antitumor, antioxidative and anti-hypoxia selenium-containing peptide mixture and preparation method thereof

Abstract

The invention relates to a selenium-containing peptide mixture. The selenium-containing peptide mixture is a histone deacetylase pure natural synergistic combined inhibitor which is prepared by using traditional Chinese medicine ginseng, salvia miltiorrhiza, aloe, fructus lycii, coix seeds, poria cocos, Chinese date, kudzuvine roots, rubia cordifolia, selenium and the like as original raw materials and utilizing a modern microbial fermentation technology and has a completely new chemical structure. The selenium-containing peptide mixture comprises combination compounds such as selenium-containing cyclic peptide, short chain fatty acid, electrophilic flavone and the like and belongs to a novel tumor epigenetic regulation medicament with an antitumor effect. Different from a conventional tumor treatment medicament, the selenium-containing peptide mixture carries out saturation attack by abnormal epigenetic inheritance of cancer cells as the target, takes the integral antitumor effect by inducing the immune monitoring and immune killing effects of a patient, is antioxidative and anti-hypoxia, is purely natural and has no chemical pollution.

Description

1. Technical field: [0001] The invention relates to a "selenopeptide mixture" medicine and a preparation method thereof, in particular to an anti-tumor, anti-oxidation, and anti-hypoxia selenopeptide mixture and a preparation method thereof. 2. Background technology: [0002] Tumor is a major intractable disease that threatens human life and health. Human beings have experienced a long history of changes in the treatment of tumors. Anti-tumor drugs are one of the important treatment methods. With the deepening of research and the development of science and technology, anti-tumor drugs are constantly improving with the discovery of new targets. [0003] In recent years, scientists have conducted in-depth studies on tumors and found that although the causes of tumor occurrence and development are very complex, they are all closely related to gene expression and abnormal activity of gene expression products in the final analysis. At the same time, the deterioration of the prim...

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Problems solved by technology

However, new problems have emerged in the current research and development work: (1), the existing inhibitors are used alone, and the efficacy is low; (2), most of the inhibitors are easily degraded in the body, have short half-lives, and are unstable; (3), The transcriptional inhibition of hematopoietic factors GATA-1 and 10 can cause adverse reactions such as thrombocytopenia; (4), there is also a certain anti-tumor function of the trace element selenium, but selenium ions are precipitated in the neutral and alkaline environment of the small intestine, Seriously affect the effect

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