Red reed seed granules, as well as preparation method and application thereof

A granule, fresh reed root technology, applied in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of lack of new products, large damage, and gastrointestinal irritation in the field of gout treatment, and achieve prevention and treatment of gout disease. , Easy to use, good curative effect

Active Publication Date: 2012-07-18
ZHEJIANG ADAMERCK BIOPHARMLABS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the past 50 years, there has been a lack of new products in the field of gout treatment, and existing drugs have the defect of irritating and damaging the gastrointestinal tract of patients

Method used

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  • Red reed seed granules, as well as preparation method and application thereof
  • Red reed seed granules, as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0018] The preparation method of the oat flour is as follows: peel the naked oats, depilate them, bake them at 85° C. for 4 hours, then crush them mechanically, test them, and steam sterilize them.

[0019] The preparation method of the fresh reed rhizome extract is as follows: crush the fresh reed rhizome, extract twice with 10 times the amount of water at 80°C for 2 hours each time, concentrate the extract under reduced pressure, spray dry, pulverize, and sieve to obtain the product.

[0020] The preparation method of the carrot extract is as follows: crush the carrot and extract it with water at 80°C for 3 times, the first extraction with 10 times the amount of water for 2 hours; the second extraction with 8 times the amount of water for 1.5 hours; the third extraction with 6 times the amount of water 1.0h, filtered, concentrated, spray-dried, pulverized, sieved, and obtained.

[0021] The preparation method of the celery seed extract is as follows: celery seed is extracted...

Embodiment 1

[0022] Example 1 (oat flour: fresh reed root extract: carrot extract: celery seed extract weight ratio is 29:10:1:2)

[0023] Pass 2900 grams of oat flour, 1000 grams of fresh reed root extract, 100 grams of carrot extract, and 200 grams of celery seed extract through a 60-mesh sieve respectively, and set aside. The sifted raw materials: 1000 grams of fresh reed root extract, 100 grams of carrot extract, 2900 grams of oat flour are dry mixed for 10 to 15 minutes, and 80% ethanol solution is added to prepare a soft material; sieved through 12 to 16 mesh Granules; dried at 50°C to 55°C; whole grains; then add 200 grams of celery seed extract after sieving; mix well; divide into bags, each bag contains 4.2 grams of dry granules, a total of 1000 bags; namely have to.

Embodiment 2

[0024] Example 2 (the weight ratio of oat flour: fresh reed root extract: carrot extract: celery seed extract is 27:9:1.1:2)

[0025] Pass 2,700 grams of oat flour, 900 grams of fresh reed root extract, 110 grams of carrot extract, and 200 grams of celery seed extract through a 60-mesh sieve, and set aside. The sifted raw materials: 900 grams of fresh reed root extract, 110 grams of carrot extract, and 2700 grams of oat flour are dry mixed for 10 to 15 minutes, and an appropriate amount of 80% ethanol solution is added to prepare a soft material; sieved through 12 to 16 mesh Granules; dried at 50°C to 55°C; whole grains; then add 200 grams of sieved celery seed extract; mix well; divide into bags, each bag contains 3.91 grams of dry granules, 1000 bags in total; have to.

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Abstract

The invention provides red reed seed granules, which consist of pure natural plant food oat kernel flour, fresh reed rhizome extract which is extracted from plants, carrot extract and celery seed extract. The red reed seed granules are prepared by the steps of: screening the components through a 60-mesh screen; carrying out dry mixing on the fresh reed rhizome extract, the carrot extract and the oat kernel flour; adding proper 80 percent ethanol solution to prepare a soft material; screening and pelletizing, drying and granulating; adding the celery seed extract for uniformly mixing; and sub-packaging with bags. According to the red reed seed granules, the capability of removing uric acid from urine of a human body can be remarkably improved, and deposition of uric acid in the body can be reduced, so that calculus can be dissolved, gout is prevented from relapse, and the red reed seed granules can be applied to preparation of a medicament for preventing and treating gout and hyperuricemia. Pure natural plant foods and plant extract are adopted as raw materials, so that the red reed seed granules have the advantages of unique prescription, reasonable proportion, easily available raw materials, convenience for use, good curative effect, safety and sanitation, proper price and low cost, and has wide market prospect.

Description

technical field [0001] The invention belongs to the field of pharmacy, and relates to red reed seed granules, a preparation method and application thereof. The red reed seed granule can effectively inhibit the activity of xanthine oxidase and reduce uric acid for patients with gout and hyperuricemia; it can prevent gout for people who do not suffer from gout but have a high uric acid value. Background technique [0002] In recent years, due to changes in dietary structure and increased intake of high-protein and high-purine foods, the number of patients with hyperuricemia and gout in my country is increasing day by day, catching up with or even surpassing Western countries. [0003] Xanthine oxidase catalyzes the conversion of hypoxanthine into xanthine to eventually generate uric acid. Excessive production of uric acid and / or its metabolic disorders can lead to hyperuricemia, and hyperuricemia is the biochemical basis of gout. It is also the key cause of gout. Hyperuricemi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P19/06
Inventor 漆又毛
Owner ZHEJIANG ADAMERCK BIOPHARMLABS
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