Safe stable type Karl Fischer reagent and preparation method thereof

Abstract

The invention discloses a safe stable type Karl Fischer reagent which comprises the following components in percentage by mass: 60-64 percent of diethylene glycol monomethyl ether, 8-12 percent of diethanol amine, 3.5-5.5 percent of pyridine, 12-15 percent of sulfur dioxide and 8-12 percent of iodine. The preparation method of the safe stable type Karl Fischer reagent comprises the following steps of: adding the diethylene glycol monomethyl ether, the diethanol amine and the pyridine in a reaction kettle and mixing; introducing the sulfur dioxide; after the gas is introduced, cooling the mixed solution below 25DEG C; and adding the iodine and stirring the mixed solution until the iodine is completely dissolved and obtaining a target product. According to the safe stable type Karl Fischer reagent and the preparation method thereof disclosed by the invention, original poisonous dangerous solvent is replaced by a safety type solvent, so that the safe stable type Karl Fischer reagent is non-poisonous, safe, environment-friendly and stable in quality; and after the safe stable type Karl Fischer reagent is stored for a long time, the titer is still within a usable range.

Description

Technical field [0001] The invention involves chemical fields, especially a safe and stable Kar Fei test agent and their preparation methods. Background technique [0002] Karl-Fischer Reagent, also known as the Casa reagent, is a commonly used reagent that analyzes water content. It has a wide range of applications in neighborhoods such as medicine, chemical industry, and oil processing.Moisture is a recognized general method internationally and domestic. [0003] The existing Carbayo reagents are hybrid reagents for pyridine, methanol, iodine, and sulfur dioxide. Among them, due to pyridine have a bad odor and pollution operation environment; methanol is high toxic, endangers human health, has poor storage stability, short placed time, and flammable.Therefore, the existing type of Carl Fei test agent is a first -class flammable liquid, which has strict requirements for procurement, transportation, and storage, and is harmful to the health of users, which is not conducive to env...

AI Technical Summary

Problems solved by technology

[0003] Existing Karl Fischer reagent is a mixed reagent of pyridine, methanol, iodine and sulfur dioxide, wherein because pyridine has a foul smell, it pollutes the operating environment; methanol is highly toxic, endangers human health, has poor storage stability, short storage time, and is flammable

Therefore, the existing Karl Fischer reagent is a first-class flammable liquid, which has strict requirements on procurement, transportation and storage, and is harmful to the health of users and is not conducive to environmental protection.

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