18 results about "Disulfur dioxide" patented technology

The present application relates to a kind of catalyst for preparing ethylene sulfite, the preparation method of ethylene sulfite, the catalyst includes organic aluminum compound and amine, the molar ratio of the organic aluminum compound and the amine is 1-5:1.The preparation method of ethylene sulfite includes the reaction of contacting ethylene oxide with sulfur dioxide in the presence of the catalyst.The quaternary ammonium salt in the catalyst of the present application and trialkylaluminum are excited by phase transfer and coordination, etc.Effect, monomer ring-opening of ethylene oxide, promote SO2 and ethylene oxide to react to generate ethylene sulfite, and then high-purity ethylene sulfite is prepared with high yield.

The invention belongs to the field of chemical reagent moisture detection, and particularly relates to a coulometry Karl Fischer reagent for aldehyde ketone moisture detection and a preparation method of the coulometry Karl Fischer reagent. The coulometry Karl Fischer reagent for aldehyde ketone moisture detection is prepared from the following components in parts by weight: 1 to 15 percent of imidazole, 1 to 15 percent of 2-methylimidazole, 25 to 70 percent of ethylene glycol monomethyl ether, 5 to 30 percent of trichloromethane, 2 to 30 percent of trifluoroethanol, 2 to 10 percent of sulfur dioxide, 1 to 10 percent of methyl iodide, 0.1 to 5 percent of tetrabutylammonium iodide and 0.1 to 5 percent of iodine. The method does not contain hydroxyl compounds, effectively inhibits the generation of side reactions in detection, ensures the detection accuracy, and improves the product stability and effectively shortens the instrument equilibrium time by adding iodomethane and tetrabutylammonium iodide.

The application belongs to the technical field of chondroitin sulfate preparation, and particularly relates to application and application method of liquid sulfur dioxide in preparation of chondroitin sulfate or chondroitin sulfate salt. In the application, liquid sulfur dioxide is used as a solvent to perform sulfonation modification treatment on unsulfated chondroitin, on the one hand, the use of traditional high-boiling organic reagents is avoided, the difficulty of three-waste treatment is reduced, and the process is more green and environmentally friendly; on the other hand, the post-treatment operation of the sulfonation reaction is simpler, and sulfur dioxide can be removed from the system by only temperature control or pressure adjustment, so that solvent residues possibly existing in the final product are avoided, and the product is safer. In addition, by adjusting the key conditions of the sulfonation reaction, the proportion of chondroitin sulfate with 6 independent sulfation in the disaccharide unit of the sulfonation product is 70% to 90%, the reaction is stable and reliable, and the sulfonation rate is high.

The application provides a novel ratio near-infrared fluorescent probe for detecting sulfur dioxide, a preparation method and application of the fluorescent probe, the fluorescent probe is Cou-Oxo, the preparation method comprises the following steps: dissolving a compound Cou-CN and a compound 3 in toluene, adding piperidine to catalyze a reaction, refluxing at 114-116 DEG C under a nitrogen atmosphere for 4.8-5.2 hours, and after the reaction is completed, the fluorescent probe Cou-Oxo is obtained through purification.The ratio fluorescent probe has good light emitting characteristics, can effectively detect sulfur dioxide derivatives, has the potential of quantitative detection, and the lower limit of detection is 0.942 muM.The ratio fluorescent probe has a fast response to the detection of sulfur dioxide derivatives, has good light emitting characteristics and stability, and can detect HSO3 ‑ in a physiological pH range of 7-9; the ratio fluorescent probe has lower biological toxicity and is suitable for cell imaging.

The application discloses a method for continuously preparing high-purity sulfolane, and belongs to the technical field of organic synthesis. By introducing a solvent and a stable free radical type polymerization inhibitor, the self-polymerization of butadiene is effectively inhibited. By adopting a cooling crystallization mode to remove sulfur dioxide, the thermal decomposition of sulfolene sulfone is avoided, high yield and high purity are realized, the service life of a hydrogenation catalyst is not affected, and the catalyst can be completely reused. The cooling crystallization also realizes the separation of the polymerization inhibitor and sulfolene sulfone. The polymerization inhibitor is dissolved in the solvent and recycled, and does not enter the hydrogenation system, so that the final sulfolane product has a purity of above 99.9% and has no chromaticity problem. The process saves energy consumption, the solvent has wide universality, operation is simple, the process is safe and environment-friendly, easy to scale up, and meets the green production requirements.

The invention relates to a method for manufacturing sulphuric acid, which involves converting sulphur dioxide SO2 into sulphur trioxide SO3, by injecting gaseous sulphur dioxide into a converter (1) inside which at least one mass (2) of a catalyst for the conversion is present, and according to which, during phases in which the injection of the gaseous sulphur dioxide is stopped, the space inside the converter (1) is heated in such a way as to maintain a minimum temperature of 200° C., and preferably 250° C., within each catalyst mass (2), characterized by the fact that the stopping of the injection of the sulphur dioxide is slaved to the starting of the heating, and vice versa.

The utility model belongs to the technical field of sulfuryl fluoride preparation equipment, and particularly relates to a reactor for preparing sulfuryl fluoride, which comprises a bottom frame, an outer barrel fixedly connected to the top of the bottom frame, a reaction barrel fixedly connected to the inside of the outer barrel, a bearing fixedly connected to the inner side of the reaction barrel, and a rotating frame fixedly connected to the inner side of the bearing. The rotating shaft drives the inner ring to rotate so as to drive the connecting rods to enable the outer ring to drive the spiral columns to rotate, the spiral columns are rotated by starting the motor, and the upper and lower adjacent spiral columns are arranged in a staggered manner, so that potassium fluoride particles attached to the outer sides of the spiral columns can be in full contact with sulfur dioxide and fluorine gas, and the reaction is more thorough; therefore, the preparation efficiency is improved.

The present application relates to a method for preparing sulfuryl fluoride, the method comprising: (1) providing a reaction stream comprising an organic base-hydrogen fluoride complex; (2) introducing sulfur dioxide and chlorine into the reaction stream comprising the organic base-hydrogen fluoride complex, and reacting to form a product stream comprising sulfuryl fluoride. The method described in the present application has mild reaction conditions, high product yield and purity, material recycling, less waste, etc., and is suitable for industrial production.

A method for preparing cyano sulfonyl fluoride compounds is provided. Oxime ether compounds are used as free radical precursors, and under the condition of photocatalyst regulation, and in combination with the strategy of free radical sulfur dioxide insertion, the process involves photocatalytic oxidation, C—C bond cleavage rings, free radical SO2 insertion and fluorination to achieve cyano / fluorosulfonyl reaction of oxime ether, yielding cyano sulfonyl fluoride products.

The application discloses a synthesis method of a beta-fluorosulfonyl sulfone compound and application thereof, and belongs to the technical field of chemical synthesis and medicinal chemistry. The method comprises the following steps: under a protective atmosphere, potassium trifluoroborate compound, a photocatalyst, a sulfur dioxide source, a hydrogen source and ethylenesulfonyl fluoride are mixed in an organic solvent, and reaction is carried out under light irradiation to obtain the beta-fluorosulfonyl sulfone compound. The application can realize preparation of a series of beta-fluorosulfonyl sulfone compounds, provides a new synthesis method for synthesis of the beta-fluorosulfonyl sulfone compound, and sulfone groups and sulfonyl fluoride groups are part of the structures of various drug molecules, so that the application is expected to be widely applied in the fields of organic synthesis, drug development and polymer materials.

The application provides a kind of construction of indole derivative fluorescent probe for detecting viscosity and sulfur dioxide in vivo, and belongs to the field of biological detection.The fluorescent probe (denoted as BIC) of the application utilizes the strong nucleophilicity of sulfur dioxide, and realizes the specificity selection of sulfur dioxide by generating new product BIC-SO2 through Michael addition reaction with double bond in the structure of probe; in addition, benzene ring and indole in BIC structure can freely rotate in low viscosity environment, resulting in non-radiation consumption of excited state energy, showing very weak fluorescence; in high viscosity solution, the free rotation of probe is inhibited, resulting in the recovery and enhancement of probe fluorescence, showing very strong fluorescence. Therefore, the fluorescent probe of the application can simultaneously detect viscosity and sulfur dioxide in vivo.

The invention discloses a method for efficiently preparing methanesulfonic acid from methane, which comprises the following reaction processes: introducing methane, sulfur dioxide and oxygen into a fixed bed reactor filled with a catalyst, and carrying out gas-liquid separation on reaction components to obtain methanesulfonic acid, the catalyst is a supported catalyst comprising an active metal and a carrier; the active metal comprises at least one noble metal selected from palladium, platinum and iridium and at least one other metal selected from vanadium, molybdenum, iron and potassium. The method has the advantages of simple process, high product yield, mild reaction conditions, easiness in industrialization and the like.

The present application relates to a kind of nickel cobalt hydroxide mass promotion method, the present application directly uses sulfur dioxide and air oxidation after removing iron aluminum, manganese in the liquid after removing iron aluminum, directly convert into manganese dioxide and other manganese oxides, remove manganese first, save the cost of continuous reducing agent;After removing manganese, the liquid is treated to form conversion alkali crystal slurry, itself contains little manganese, and the insoluble and non-reactive manganese oxide caused by excessive alkali problem will not be brought, so that the manganese content in nickel cobalt hydroxide product is reduced, and the quality of nickel cobalt hydroxide product is improved.

The application provides a method for preparing sulfinic acid compounds, sulfinic acid salt compounds, sulfonic acid salt compounds and sulfonyl compounds through sulfinylation, comprising the following steps: under the conditions of a protective atmosphere and light, performing a sulfinylation reaction on an alkyl compound and a sulfur dioxide donor under the condition of a catalyst to obtain an alkyl sulfinic acid compound. The main catalyst comprises a metal salt, and the metal elements in the metal salt comprise one or more of Fe, Cu and Ce; the cocatalyst comprises one or more of chlorosilane, a tetraalkylammonium chloride, an alkali metal chloride and hydrochloric acid. The method in the application has high catalytic efficiency (TON>350000, TOF>50000 / h), high selectivity (the conversion selectivity of sulfinic acid is >99%), high conversion rate (sulfinic acid is close to complete conversion), and is low in cost, high in atomic economy, basically free of waste in the production process, and green, low-carbon and environmentally friendly.

The present application relates to a catalyst for preparing ethylene sulfite, the catalyst comprising a hydrocarbyl borane and a nitrogen-containing organic compound, the molar ratio of the hydrocarbyl borane and the nitrogen-containing organic compound being 0.1-0.5:1. The present application also relates to a method for preparing ethylene sulfite, the method comprising: contacting ethylene oxide with sulfur dioxide in the presence of the catalyst described in the present application. The catalyst of the present application can well catalyze the synthesis of ethylene sulfite, the preparation process conditions are easy to control, and high-purity ethylene sulfite can be prepared at a high yield.

A first method for determining moisture content in a sample includes the steps of providing a reagent comprising sulfur dioxide or a derivative thereof; a base; optionally a hydrogen halide or a hydrogen halide donor; a solvent; and a sulfonic acid; and titrating the sample with the reagent. A second method for determining moisture content in a sample includes the steps of providing the reagent described above, mixing the sample with the reagent; and adding an iodine source to the sample and / or the reagent. The reagent can alternatively consist essentially of sulfur dioxide or a derivative thereof; imidazole and / or a derivative thereof; optionally a hydrogen halide or a hydrogen halide donor; acetonitrile; methanesulfonic acid; and methanol and / or ethanol.

The invention is directed toward the production of 3-methylsulfolene using isoprene and can be used in the chemical and petrochemical industry. A process of producing 3-methylsulfolene using isoprene comprises reacting isoprene with sulfur dioxide in a cyclization reaction in the presence of an isoprene polymerization inhibitor and a tenfold excess of solvent relative to the amount of 3-methylsulfolene produced, at a temperature of 60-80°C and a pressure of 1.0 MPa for 1-2 hours, and subsequently purifying and drying the 3-methylsulfolene. The process is carried out in a plant for producing 3-methylsulfolene which consists of a batch reaction apparatus having an agitator and a heat exchange jacket, a fractionating column, pumps, feedstock tanks, final product tanks, intermediate tanks, a sulfur oxidation unit, a filter unit, and a unit of heat exchangers that are interconnected by a system of pipes with shutoff valves. The process of producing 3-methylsulfolene provides a high yield of high-purity target product, prevents large losses of solvent and enables more efficient use of sulfur, and can be used for industrial-scale production with the aid of the proposed plant, which provides for efficient production of 3-methylsulfolene.

The invention discloses a water quality total phosphorus rapid detection reagent and a preparation method thereof, and relates to the technical field of water quality total phosphorus detection, and the water quality total phosphorus rapid detection reagent comprises a digesting agent, a color developing reagent and a reducing reagent. Anhydrous ytterbium trifluoromethanesulfonate added into the color developing reagent can activate a polyethylene glycol diglycidyl ether epoxy group, the reaction time of the color developing reagent is shortened, ammonium molybdate tetrahydrate is added to dissociate high-purity molybdate to serve as a core active component of the reaction, polyethylene glycol diglycidyl ether and molybdate react accurately, and the purity of the molybdate is improved. Molybdate with a uniform structure is formed, and the storage stability is improved. According to the reduction reagent, through the synergistic effect between thiourea dioxide and an L-cysteine material, L-cysteine does not influence the directional reduction capacity of thiourea dioxide, and a reduction product of thiourea dioxide does not interfere the complexing function of L-cysteine, so that the reduction reagent has the advantages of efficient reduction and long-term stable preservation.