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Traditional Chinese medicine composite for treating diabetic cardiopathy and preparation method and applications thereof

A technology for diabetic heart disease and composition, which is applied in the field of traditional Chinese medicine composition for treating diabetic heart disease and its preparation field, can solve problems such as toxic and side effects of chemical drugs, and achieve the effects of no toxic and side effects, strict compatibility and low price

Inactive Publication Date: 2013-07-17
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Hyperglycemia is one of the persistent risk factors for cardiovascular disease. The risk of cardiovascular disease in diabetic patients increases with the increase of blood sugar. At present, Western medicine mostly uses hypoglycemic drugs for treatment, but long-term use of chemical drugs causes toxic and side effects. Need a kind of effective, can play the treatment diabetic heart disease traditional Chinese medicine that can play to have good effect by most people

Method used

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  • Traditional Chinese medicine composite for treating diabetic cardiopathy and preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1: Take 20g of Astragalus, 60g of Polygonatum, 10g of Corydalis Corydalis, 15g of Trichosanthes Root, 20g of Angelica, 15g of Curcuma, 5g of Safflower, 30g of Salvia, 20g of Hawthorn, 40g of Rehmannia, 5g of Licorice, and combine the eleven medicinal materials, add water Decocting twice, adding water for the first time is 8 times the weight of the medicinal material, decocting for 1 hour, adding water for the second time is 6 times the weight of the medicinal material, decocting for 1 hour, combining the decoction, decocting at 0.07MPa, 60-70℃ The relative density is 1.10 when concentrated under pressure to 65 DEG C, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stir, let stand for 24 hours, the filtrate reclaims ethanol under reduced pressure and concentrates, and the filtrate is in 0.07MPa, condensed under reduced pressure at 65°C to a relative density of 1.30 at 65°C, spray drying (conditions: the inlet air temperature is 120°C, the outlet...

Embodiment 2

[0027] Example 2: Take 30g of astragalus, 50g of sealwort, 20g of Corydalis, 10g of Trichosanthes root, 30g of angelica, 10g of turmeric, 10g of safflower, 20g of salvia miltiorrhiza, 30g of hawthorn, 30g of rehmannia glutinosa, 10g of licorice, combine the eleven medicinal materials, add water Decoct twice, add water for 10 times the weight of the medicinal material for the first time, decoct for 1.5h, add water for the second time 8 times the weight of the medicinal material, decoct for 1.5h, combine the decoction, 0.07MPa, 60-70℃ Concentrate under reduced pressure until the relative density is 1.15 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, and let it stand for 24 hours, the filtrate recovers ethanol under reduced pressure and concentrates, The filtrate was concentrated under reduced pressure at 0.07MPa and 65°C to a relative density of 1.25 at 65°C, and spray-dried (conditions were that the inlet air temperature was 100°C, the outlet a...

Embodiment 3

[0028] Example 3: Take 40g of Astragalus, 40g of Polygonatum, 30g of Corydalis Corydalis, 5g of Trichosanthes root, 40g of Angelica sinensis, 5g of Curcuma, 15g of Safflower, 10g of Salvia miltiorrhiza, 40g of hawthorn, 20g of Rehmannia glutinosa, 15g of licorice, and combine the eleven medicinal materials, add water Decocting twice, adding water for the first time is 12 times the weight of the medicinal material, decocting for 2 hours, adding water for the second time is 10 times the weight of the medicinal material, decocting for 2 hours, combining the decoction, decocting at 0.07MPa, 60-70℃ The relative density is 1.20 when concentrated under pressure to 65 DEG C, add 95% (v / v) ethanol to make the alcohol content reach 65% (v / v), stir, let stand for 24 hours, the filtrate reclaims ethanol under reduced pressure and concentrates, and the filtrate is in 0.07MPa, condensed under reduced pressure at 65°C to a relative density of 1.25 at 65°C, spray drying (conditions: the inlet ...

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Abstract

The invention discloses a traditional Chinese medicine composite. The goal of treating diabetic cardiopathy is achieved through tonifying Qi and promoting Qi circulation to relieve pain and promoting blood circulation to remove blood stasis. In order to achieve the goal, the technical scheme provided by the invention is that active ingredients contained by the traditional Chinese medicine composite are prepared by proportioning the following raw materials in parts by weight: 20-40 parts of Astragalus mongholicus, 40-60 parts of rhizoma polygonati, 10-30 parts of corydalis tuber, 5-15 parts oftrichosanthes kirilowii Maxim, 20-40 parts of Angelica sinensis, 5-15 parts of radix curcumae, 5-15 parts of red flower, 10-30 parts of radix salviae miltiorrhizae, 20-40 parts of hawthorn, 20-40 parts of radix rehmanniae recen and 5-15 parts of liquorice, and a corresponding preparation method is adopted. The traditional Chinese medicine composite has the effects of tonifying the Qi and promoting the Qi circulation to relieve the pain, promoting the blood circulation to remove the blood stasis and treating the diabetic cardiopathy.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating diabetic heart disease, a preparation method and application thereof. Background technique [0002] Diabetic heart disease is one of the leading causes of death in people with diabetes, especially in people with type 2 diabetes. Diabetic heart disease in a broad sense includes coronary atherosclerotic heart disease (coronary heart disease), diabetic cardiomyopathy, and diabetic cardiac autonomic neuropathy. Diabetic heart disease often has an earlier onset than non-diabetic patients. Diabetic patients with coronary heart disease often present as painless myocardial infarction, with relatively large infarct size, more transmural infarction, more severe disease, poorer prognosis, and lower mortality rate. higher. [0003] The pathogenesis of diabetic heart disease has not been fully elucidated, but from ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P3/10A61P9/00A61P9/10
Inventor 陈龙王中越吴皓
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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