Traditional Chinese medicinal composition for treating paradentitis and preparation method thereof and toothpaste
A composition and periodontitis technology, applied in the field of traditional Chinese medicine, can solve the problems of unsatisfactory periodontitis curative effect, short drug action time, and many medication times, and achieve the effects of significant curative effect, no toxic side effects, and high cure rate.
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[0075] When the dosage form of the Chinese medicine composition of the present invention is decoction, its preparation method comprises the following steps:
[0076] 1. The components are mixed in proportion, crushed and sieved into a powder of 100 mesh to 150 mesh;
[0077] 2. Add the powder obtained in step 1 into cold water and soak for 24 to 36 hours, decoct with a slow fire for 1 to 2 hours, filter the decoction to obtain the first filtrate, the quality of the added cold water It is 3 to 5 times the mass of the powder obtained in the first step;
[0078] 3. Add the filter residue obtained by filtering in the second step into cold water again, decoct with a slow fire for 1 hour to 2 hours, and filter to obtain the second filtrate. The quality of the added water is the same as that in the second step;
[0079] 4. Combine the two filtrates to obtain the decoction.
[0080] When the dosage form of the Chinese medicine composition of the present invention is tablet, its prep...
Embodiment 1
[0101] The toxicity test of embodiment 1 Chinese medicine composition of the present invention
[0102] 1. Acute toxicity:
[0103] Test drug:
[0104] 60g Anemarrhena, 48g gypsum, 18g reed root, 16g trichosanthes, 25g coptis, 14g flavescens, 10g Pulsatilla, 17g Moutan bark, 15g Cimicifuga, 13g coix seed, 10g Poria cocos, 8g Imperata rhizome, 14g astragalus, 8g Atractylodes macrocephala, Mix 7g of licorice, 10g of Ligustrum lucidum, 5g of Eclipta chinensis, and 10g of fenugreek, and grind them into 100-mesh powder; soak the obtained powder in 950g of cold water for 36 hours, and decoct with a slow fire for 2 hours. Liquid was filtered to obtain the first filtrate; the filter residue obtained by filtration was added to 950 g of cold water again, decocted with a slow fire for 2 hours, and the second filtrate was obtained by filtration; the two filtrates were combined to obtain a decoction.
[0105] Experimental procedure:
[0106] Get 40 ICR mice (provided by Beijing Weitong ...
Embodiment 2
[0112] The preparation of the decoction of embodiment 2 Chinese medicine composition of the present invention
[0113] 60g Anemarrhena, 48g gypsum, 18g reed root, 16g trichosanthes, 25g coptis, 14g flavescens, 10g Pulsatilla, 17g Moutan bark, 15g Cimicifuga, 13g coix seed, 10g Poria cocos, 8g Imperata rhizome, 14g astragalus, 8g Atractylodes macrocephala, Mix 7g of licorice, 10g of Ligustrum lucidum, 5g of Eclipta chinensis, and 10g of fenugreek, and grind them into 100-mesh powder; soak the obtained powder in 950g of cold water for 36 hours, and decoct with a slow fire for 2 hours. Liquid was filtered to obtain the first filtrate; the filter residue obtained by filtration was added to 950 g of cold water again, decocted with a slow fire for 2 hours, and the second filtrate was obtained by filtration; the two filtrates were combined to obtain a decoction.
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