Vitamin B12 complex fermenting addition agent and application method thereof to fermenting vitamin B12

A technology of compound fermentation and application method, applied in the direction of microorganism-based method, biochemical equipment and method, fermentation, etc., to achieve the effect of ensuring supply, ensuring fermentation effect, and improving fermentation output
CN102719504AActive Publication Date: 2012-10-10山东祥维斯生物科技股份有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
山东祥维斯生物科技股份有限公司
Publication Date
2012-10-10

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Abstract

The invention discloses a vitamin B12 complex fermenting addition agent and an application method thereof to fermenting vitamin B12. The vitamin B12 complex fermenting addition agent comprises the following components in percentage by mass of: 90-98% of betaine, 0.15-0.55% of vitamin B complex and 1.45-9.85% of complex amino acid, wherein the vitamin B complex comprises the following components in mass percentage: 30-55% of thiamine, 10-25% of pyridoxine hydrochloride and 40-55% of folic acid; and the complex amino acid comprises the following components in percentage by mass of: 5-10% of lysine, 10-15% of serine, 10-15% of glutamic acid, 30-35% of asparagine and 30-40% of aspartic acid. The complex fermenting addition agent disclosed by the invention is added into the fermented vitamin B12 so that the supply of various nutrient components in a fermentation process is ensured and the fermentation output of the vitamin B12 is effectively improved.
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Description

technical field

[0001] The present invention relates to vitamin B 12 The preparation of, specifically relates to a kind of for vitamin B 12 Composite fermentation aid in fermentation preparation and application method thereof. Background technique

[0002] Vitamin B 12 It is a cobalamin compound, which is mainly used clinically to treat pernicious anemia, and is also used to treat various nervous system diseases and certain liver diseases.

[0003] Vitamin B present 12 Mainly rely on Pseudomonas denitrification made by aerobic fermentation. The main components of the fermentation medium include organic carbon sources, organic nitrogen sources, betaine, a small amount of inorganic salts, and the like. Among them, the trace element nutritional factors attached to organic matter are indispensable factors for normal function and metabolic activities. As cofactors, they participate in the regulation of many microbial metabolisms and are a key link in the regulation of microb...

Claims

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