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Medicine composition for accelerating healing after fracture surgery, preparation method and application

A composition and post-operative technology, applied in the field of pharmacy, can solve the problems of patients with local infection and non-union, affecting fracture treatment, etc.

Inactive Publication Date: 2012-10-24
朱崇田
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Western medicine such as antibiotics is often abused after fracture surgery, resulting in local infection and non-union of patients, and new viruses and bacteria emerging one after another, seriously affecting the treatment of fractures

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0062] The present invention provides the preparation method of above-mentioned pharmaceutical composition, it comprises:

[0063] In the first step, Achyranthes bidentata, epimedium, walnut kernel, small bark bone, Eucommia ulmoides, Cistanche, and psoraleae are mixed in proportion, and methanol with an alcohol concentration of 70% to 80% is used as a solvent, and percolation method is used for each Slowly percolate at a speed of 1-3ml per minute, collect the percolation liquid, concentrate under reduced pressure and dry to obtain a dry paste, which is crushed into 100-200-mesh powder. The quality of the added methanol is 3-3% of the mass of the mixture in the first step. 5 times;

[0064] In the second step, mix the remaining components in proportion, crush them into powder, add distilled water 3 to 6 times the mass of the powder, decoct for 2 to 4 hours, filter to obtain the first filtrate, add the filter residue to the 2 to 4 times of distilled water, decocting for 1 to 2...

Embodiment 1

[0076] The powder 1 that the present invention prepares of embodiment 1

[0077]Mix 47g of Achyranthes bidentata, 32g of Epimedium, 25g of walnut kernel, 30g of small bone, 24g of Eucommia, 42g of Cistanche, and 51g of psoralen, and use 1000g of methanol with an alcohol concentration of 80% as a solvent. Slowly infiltrate at a rate of 2ml, collect the percolation liquid, concentrate under reduced pressure and dry to obtain a dry paste, which is crushed into a 100-mesh powder, and 28g of Caulis Spatholobus, 40g of Panax notoginseng, 17g of natural copper, 33g of Rhizoma Chuanxiong, 24g of Motherwort, sea breeze Mix 23g rattan, 81g astragalus, 67g yam, 18g tangerine peel, 13g woody scent, and 10g calamus calamus, grind them into powder, add 1500g of distilled water, decoct for 3 hours, filter to obtain the first filtrate, add the filter residue to 300g of distilled water, Decoct for 2 hours, filter to obtain the second filtrate, combine the filtrates, concentrate to remove 3 / 4 v...

Embodiment 2

[0082] The powder 2 that embodiment 2 the present invention prepares

[0083] Mix Achyranthes bidentata 50g, Epimedium 34g, walnut kernel 28g, small bark bone 32g, Eucommia 27g, Cistanche 46g, psoralen 56g, use methanol concentration of 80% as solvent 1000g, adopt percolation method Slowly infiltrate at a rate of 2ml, collect the percolation liquid, concentrate under reduced pressure and dry to obtain a dry paste, which is crushed into a 100-mesh powder, with 30g of Caulis Spatholobus, 41g of Panax notoginseng, 18g of natural copper, 36g of Rhizoma Chuanxiong, 25g of Motherwort, sea breeze Mix 26g rattan, 84g astragalus, 69g yam, 19g tangerine peel, 13g woody fragrance, and 12g calamus calamus, grind them into powder, add 1500g of distilled water, decoct for 3 hours, filter to obtain the first filtrate, add the filter residue to 300g of distilled water, Decoct for 2 hours, filter to obtain the second filtrate, combine the filtrates, concentrate to remove 3 / 4 volume of water, a...

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PUM

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Abstract

The invention provides a medicine composition for accelerating healing after a fracture surgery, a preparation method and application. The medicine composition comprises chaff flower root, epimedium herb, walnut kernels, common gendarussa herb, eucommia bark, cistanche, semen psoraleae, caulis spatholobi, pseudo-ginseng, native copper, rhizoma Chuanxiong, motherwort, caulis piperis futokadsurae, radix astragali, Chinese yam, dried orange peel, costus root and acorus gramineus. By the aid of the medicine composition, secretion of growth factors can be promoted, local blood circulation and metabolic level of fracture can be promoted, metabolism is accelerated, and the fracture rapidly heals.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a pharmaceutical composition for accelerating the healing speed after fracture operation. Background technique [0002] Fracture is a common clinical disease and frequently-occurring disease. The local bruise, pain, deformity, and movement disorder caused by fracture have seriously affected people's daily life. Injury, increased bruising and pain in the affected limb, slowing down the fracture healing process. [0003] Fracture healing is an extremely complex process of bone tissue regeneration and repair, which is affected and regulated by many systemic and local factors. About 5% to 10% of fractures have delayed union or nonunion due to various reasons, which seriously affects people's survival. Quality, how to accelerate fracture healing and improve healing quality has always been a topic of common concern in the medical community. [0004] Western medicines such as antibio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P19/08A61K33/26
Inventor 朱崇田杨雪
Owner 朱崇田
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