Centrifugal micro-fluidic chip for detecting chromium ion form in water body and preparation method of centrifugal micro-fluidic chip

A microfluidic chip and detection chip technology, applied in chemical instruments and methods, measuring devices, laboratory containers, etc., can solve problems such as no substantial breakthrough, achieve good application prospects, shorten detection time, The effect of reducing the dosage

Inactive Publication Date: 2012-11-21
SUZHOU WENHAO MICROFLUIDIC TECH CO LTD
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  • Claims
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Problems solved by technology

However, using a disc-shaped chip, preparing microstructures and microchannels on its surface, relying on centrifugal force to drive sample microfluidics, and completing the analysis of several samples at the same time, the centrifugal microfluidic chip analysis technology is currently used in the field of rapid analysis of Cr ion forms. No substantial breakthrough yet

Method used

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  • Centrifugal micro-fluidic chip for detecting chromium ion form in water body and preparation method of centrifugal micro-fluidic chip

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Embodiment 1

[0026] The microstructure and microchannel graphics of the five-layer chip of the centrifugal microfluidic chip were designed and drawn by computer-aided design software. The microstructure and microchannel of the three-layer circular polymethyl methacrylate (PMMA) chip were processed and prepared by the numerical control CNC system, and the chips of each layer were cleaned with tap water and distilled water respectively, and the residual fingerprints, oil stains and other stains on the surface of the chip were wiped with ethanol . On the double-sided adhesive film, the required microstructures and microchannels were processed with a cutting machine. The five-layer chip was carefully aligned, glued, and pressure-sealed to make a centrifugal microfluidic chip for detecting the form of Cr ions in water. Fix the chip on the chip holder of the centrifuge through the card slot, put a small amount of quartz fiber into the hole of the quartz fiber, press it with an awl, and seal the...

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Abstract

The invention relates to a centrifugal micro-fluidic chip for detecting the chromium ion form in a water body and a preparation method of the centrifugal micro-fluidic chip. The centrifugal micro-fluidic chip is a disk type centrifugal micro-fluidic chip with a microstructure and a microchannel; the enriching and separating operation process of a Cr ion in the water body and a miniature centrifugal chromatographic column integrated on the centrifugal micro-fluidic chip is realized by using a centrifugal force generated by rotating a centrifugal machine as a driving force; and the content of total Cr in the water body and the content of Cr<6+> in an extraction solution are respectively detected by an inductively coupled plasma mass spectrometry (ICP-MS), and thus the analysis of the chromium ion form in the water body is realized. The centrifugal micro-fluidic chip realizes the integration, the micromation, the automation and the portability of the chromium ion form detection in the water body; and the centrifugal micro-fluidic chip has the characteristics of fewer reagents and samples, quickness in detection, portability and high parallel detection capability and provides a brand-new analysis technology for detecting the chromium ion form in the environment water body.

Description

technical field [0001] The invention relates to a centrifugal microfluidic chip for detecting the form of chromium (Cr) ions in a water body and a preparation method thereof. The surface of the centrifugal microfluidic chip has microstructures and microchannels, and is driven by the centrifugal force generated by the rotation of a centrifuge to realize The enrichment and separation of Cr ions in water and the extraction column integrated on the centrifugal microfluidic chip were used to detect the total Cr content in the water and the Cr content in the extract by inductively coupled plasma mass spectrometry (ICP-MS). 6+ content, so as to obtain the Cr in water 3+ The content can realize the analysis of the Cr ion form in environmental water samples, and it is mainly used in environmental science, medicine, food science and other related fields. Background technique [0002] Cr is a ubiquitous element in nature and the earth's crust. Due to the excessive use of human beings ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00G01N27/62G01N27/626
Inventor 王晓东沙俊聂富强
Owner SUZHOU WENHAO MICROFLUIDIC TECH CO LTD
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