Traditional Chinese medicine composition for treating coronary heart disease as well as preparation method and application thereof

A technology of coronary heart disease and composition, which is applied in the field of traditional Chinese medicine composition for treating coronary heart disease and its preparation, can solve the problems of large side effects, etc., and achieve the effect of strict compatibility, definite curative effect, and reasonable design

Inactive Publication Date: 2013-02-20
王颖翠
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, nitrates are commonly used in clinical practice in China, such as nitroglycerin, Xiaoxintong, Xinkang, long-acting heartache and other drug treatments. They are all chemical drugs with large side effects, and their safety is increasingly concerned

Method used

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  • Traditional Chinese medicine composition for treating coronary heart disease as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1: Take 10g Poria cocos, 20g Fushen, 40g Caulis cerevisiae, 20g Rhizoma Cyperi, 15g Atractylodes macrocephala, 25g Radix Paeoniae Rubra, 10g Radix Paeoniae Alba, 20g Tangerine Peel, 10g Sangjisheng, 50g Coix Seed, 15g Cornus officinalis, 25g Achyranthes bidentata, Dipsacus 15g, Gallinaceae 50g, Muxiang 15g, Bupleurum 20g, Malt 20g, Licorice 20g combined medicinal materials, add water to decoct twice, add water for 8 times the weight of the medicinal materials for the first time, decoct for 1 hour, and decoct for the second time Add water to 6 times the weight of the medicinal material, decoct for 1 hour, combine the decoction, concentrate under reduced pressure at 0.07MPa, 60-70°C until the relative density is 1.10 at 65°C, add 95% (v / v) ethanol to make the alcohol content Reach 85% (v / v), stir, leave standstill 24 hours, filtrate decompression reclaims ethanol and concentrates, and filtrate is condensed under reduced pressure under the condition of 0.07MPa, 65 ℃...

Embodiment 2

[0021] Example 2: Take 15g Poria cocos, 15g Fushen, 50g Caulis Cauliflower, 15g Rhizoma Cyperi, 20g Atractylodes macrocephala, 20g Radix Paeoniae Rubra, 15g Radix Paeoniae Alba, 15g Tangerine Peel, 15g Sangjisheng, 40g Coix Seed, 20g Cornus officinalis, 20g Achyranthes bidentata, Dipsacus 20g, Gallinarum 40g, Muxiang 20g, Bupleurum 15g, Malt 25g, Licorice 15g combined medicinal materials, add water to decoct twice, the first time add water 10 times the weight of the medicinal materials, decoct 1.5h, the second Add water for 8 times the weight of the medicinal material, decoct for 1.5h, combine the decoction, concentrate under reduced pressure at 0.07MPa, 60-70°C until the relative density is 1.15 at 65°C, add 95% (v / v) ethanol to make the The alcohol content reaches 75% (v / v), stir, and stand for 24 hours. The filtrate is decompressed to recover ethanol and concentrated. The filtrate is concentrated under reduced pressure at 0.07MPa and 65°C to a relative density of 1.25 at 65°...

Embodiment 3

[0022] Example 3: Take 20g Poria cocos, 10g Fushen, 60g Cauliflower radix, 10g Cyperus cyperi, 25g Atractylodes macrocephala, 15g red peony, 20g white peony, 10g tangerine peel, 20g mulberry, 30g coix seed, 25g dogwood, 15g achyranthes bidentata, Dipsacus 25g, Gallinarum 30g, Muxiang 25g, Bupleurum 10g, Malt 30g, Licorice 10g combined medicinal materials, add water to decoct twice, add water for the first time to 12 times the weight of the medicinal materials, decoct for 2 hours, and decoct for the second time Add water to 10 times the weight of the medicinal material, decoct for 2 hours, combine the decoction, concentrate under reduced pressure at 0.07MPa, 60-70°C to 65°C, the relative density is 1.15, add 95% (v / v) ethanol to make the alcohol content Reach 75% (v / v), stir, leave standstill 24 hours, filtrate decompression reclaims ethanol and concentrates, and filtrate is condensed under reduced pressure under 0.07MPa, 65 ℃ of conditions to 65 ℃ when relative density is 1.25,...

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Abstract

The invention provides a traditional Chinese medicine composition for treating coronary heart disease. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 20 parts of poria cocos, 10 to 20 parts of root poria, 40 to 60 parts of caulis polygoni multiflori, 10 to 20 parts of rhizoma cyperi, 15 to 25 parts of rhizoma atractylodis macrocephalae, 15 to 25 parts of radix paeoniae rubra, 10 to 20 parts of radix paeoniae alba, 10 to 20 parts of pericarpium citri reticulatae, 10 to 20 parts of loranthus parasiticus, 30 to 50 parts of semen coicis, 15 to 25 parts of dogwood, 15 to 25 parts of achyranthes bidentata, 15 to 25 parts of himalayan teasel root, 30 to 50 parts of endothelium corneum gigeriae galli, 15 to 25 parts of radix aucklandiae, 10 to 20 parts of radix bupleuri, 20 to 30 parts of malt, and 10 to 20 parts of liquorice. The traditional Chinese medicine composition has the effects of promoting blood circulation to remove blood stasis, and promoting Qi circulation to relieve pain, so that the purpose of treating coronary heart disease can be achieved. The invention also discloses a preparation method and application of the traditional Chinese medicine composition.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating coronary heart disease, a preparation method and application thereof. Background technique [0002] In recent years, the number of patients with coronary heart disease has been increasing, and the harm to human health has become more and more serious. How to prevent and treat coronary heart disease has become an urgent problem to be solved. Coronary heart disease is referred to as coronary heart disease. Refers to the abnormal lipid metabolism, the lipids in the blood are deposited on the smooth arterial intima, and some atherosclerotic lipids accumulate in the arterial intima to form white plaques, which are called atherosclerotic lesions. These plaques gradually increase and narrow the arterial lumen, obstructing blood flow, leading to cardiac ischemia and angina pectoris. Due to abnormal lipid metab...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61P9/10A61K35/37A61K35/57
Inventor 不公告发明人
Owner 王颖翠
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