Veterinary Shuanghuanglian preparation and preparation method for same

A Shuanghuanglian preparation technology, which is applied in the field of veterinary Shuanghuanglian preparations and its preparation, can solve the problems of low efficacy of veterinary Shuanghuanglian preparations, affecting the efficacy of veterinary Shuanghuanglian preparations, and the chicken mortality rate cannot be minimized. , to achieve the effect of avoiding loss, high efficacy and improving extraction rate

Active Publication Date: 2013-03-06
HENAN JINERKANG BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The traditional Shuanghuanglian prescription is composed of honeysuckle, scutellaria baicalensis and forsythia. However, the veterinary Shuanghuanglian preparation prepared by this prescription can not meet people's ideal requirements in preventing and treating colds, fevers and diseases in chickens, dogs and cats and other animals. Among them, Newcastle disease is a typical representative. Due to the low effect of the existing veterinary Shuanghuanglian preparation, the mortality rate of chickens cannot be minimized, which has a certain impact on my country's chicken industry.
In addition, the preparation method of traditional Shuanghuanglian preparations is generally the hydroalcoholic method. However, the extraction rate of the main active ingredients (chlorogenic acid, baicalin and forsythin) of honeysuckle, scutellaria baicalensis and forsythia is relatively low by this method. This is also one of the factors affecting the efficacy of the existing veterinary Shuanghuanglian preparations

Method used

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  • Veterinary Shuanghuanglian preparation and preparation method for same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1: Preparation of veterinary Shuanghuanglian preparation according to the present invention

[0024] Mix 125g honeysuckle, 125g skullcap, 250g forsythia and 250g astragalus and pass through a 60-mesh sieve, then add 80% ethanol solution in a mass ratio of 1:10 (mixture of raw materials of traditional Chinese medicine: 80% aqueous ethanol solution), and keep soaking at about 45°C 24h;

[0025] The ethanol aqueous solution that is completely absorbed is removed by sieve filtration, and the filtered traditional Chinese medicine raw material mixture is microwaved at 10W / g·min intensity until the temperature is 80 °C and stopped, and when the temperature drops to 70 °C, continue to microwave treatment according to the above requirements, so Microwave treatment for a total of 1 times;

[0026] Add 80% ethanol aqueous solution to the mixture of traditional Chinese medicine raw materials in a mass ratio of 1:2 (mixture of traditional Chinese medicine raw materials: 80%...

Embodiment 2

[0027] Example 2: Preparation of veterinary Shuanghuanglian preparation according to the present invention

[0028] Mix 375g honeysuckle, 375g scutellaria, 750g forsythia and 750g astragalus and pass through a 60 mesh sieve, then add 80% ethanol aqueous solution in a mass ratio of 1:15 (traditional Chinese medicine raw material mixture: 80% aqueous ethanol solution), and keep soaking at about 50°C 24h;

[0029] The ethanol aqueous solution that is completely absorbed is removed by sieve filtration, and the filtered traditional Chinese medicine raw material mixture is microwaved at 20W / g·min intensity until the temperature is 80 °C and stopped, and when the temperature drops to 70 °C, continue to microwave treatment according to the above requirements, so Microwave treatment for a total of 2 times;

[0030] To the mixture of traditional Chinese medicine raw materials in a mass ratio of 1:1 (mixture of traditional Chinese medicine raw materials: 80% aqueous ethanol solution), a...

Embodiment 3

[0031] Example 3: Preparation of veterinary Shuanghuanglian preparation according to the present invention

[0032] Mix and pulverize 500g honeysuckle, 500g skullcap, 1000g forsythia and 1000g astragalus, pass through a 60-mesh sieve, then add 80% aqueous ethanol solution at a mass ratio of 1:20 (mixture of raw materials of traditional Chinese medicine: 80% aqueous ethanol solution), and keep soaking at about 47°C 24h;

[0033] The ethanol aqueous solution that is completely absorbed is removed by sieve filtration, and the filtered traditional Chinese medicine raw material mixture is microwaved at 30W / g min intensity until the temperature is 80 °C and stopped, and when the temperature drops to 70 °C, continue to microwave treatment according to the above requirements, so Microwave treatment for a total of 3 times;

[0034] To the mixture of traditional Chinese medicine raw materials in a mass ratio of 1:2 (mixture of traditional Chinese medicine raw materials: 80% aqueous eth...

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Abstract

The invention relates to the field of veterinary medicines, and discloses a veterinary Shuanghuanglian preparation and a preparation method for the same. The raw material medicine of the veterinary Shuanghuanglian preparation disclosed by the invention is composed of the components in parts by weight: 1 part by weight of honeysuckle, 1 part by weight of scutellaria baicalensis, 2 parts by weight of fructus forsythiae, and 2 parts by weight of astragalus mongholicus. According to the invention, astragalus mongholicus is added based on the traditional Shuanghuanglian prescription, so that the veterinary Shuanghuanglian preparation prepared in this way is higher in pharmaceutical effect. Simultaneously, the preparation method for the veterinary Shuanghuanglian preparation adopts a method combining microwave with extrusion, thus the extraction rate of the active ingredients of each constituent is remarkably increased.

Description

technical field [0001] The invention relates to the field of veterinary medicine, in particular to a veterinary Shuanghuanglian preparation and a preparation method thereof. Background technique [0002] Traditional Shuanghuanglian is a compound prescription composed of honeysuckle, skullcap and forsythia. Shuanghuanglian has antibacterial, anti-inflammatory, heat-clearing and detoxifying effects in clinical practice, and is often used to prevent and treat colds, fever, cough, sore throat, etc. Chlorogenic acid and baicalin, as the main active ingredients in honeysuckle and scutellaria baicalensis in the prescription, have heat-clearing and detoxifying and obvious anti-inflammatory effects. The virus has obvious inhibitory effect. "Chinese Veterinary Pharmacopoeia" stipulates that Shuanghuanglian preparation can be used as veterinary medicine for cold and fever epidemics of chickens, dogs and cats, such as Newcastle disease in chickens, so as to prevent the harm caused by ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/634A61P11/00A61P31/12A61P29/00A61P11/14A61P11/04
Inventor 王彦彬付立亭温长印崔耀明
Owner HENAN JINERKANG BIOTECH CO LTD
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