Cistanche cell disruption method and buccal tablet prepared by cistanche micropowder obtained by method

A technology of Cistanche deserticola and cells, which is applied in the field of medicinal plant application research, can solve the problems of large particles of Cistanche deserticola powder, high preparation cost, unpleasantness, etc., and achieves the effects of avoiding reactions such as oxidation, convenient taking and small particle size.

Inactive Publication Date: 2013-04-10
孟令刚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, using this method requires low temperature, vacuum, and an oxygen-isolated environment, and the preparation cost is relatively high, and the obtained cistanche powder has relatively large particles.

Method used

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  • Cistanche cell disruption method and buccal tablet prepared by cistanche micropowder obtained by method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1 Weigh 500g of Cistanche deserticola, wash and chop it, and dry it; use a commercially available low-temperature pulverizer for Chinese herbal medicines for coarse powder at a low temperature below -10°C; freeze the coarse powder at -30°C and put it into a vibrating wall breaker for another Dry wall breaking, usually dry wall breaking means that the breaking time without solvent is 30 minutes to 60 minutes, (equipment model: SQW-25 Sanqing Micro Powder Vibration Crusher), after freezing and crushing, repeat the operation 2-4 Second, this is conducive to better wall breaking and achieving the desired particle size. The cistanche micropowder obtained is put into ultra-high pressure equipment, sterilized under high pressure treatment for 20 minutes under 350Mpa of nitrogen gas, and the pressure is released instantaneously. After repeated freezing and low-temperature crushing of Cistanche deserticola, high pressure is used to release the pressure instantaneously du...

Embodiment 2

[0022] Example 2 Weigh 500g of Cistanche deserticola, wash and slice it, and dry it; coarse powder or directly wash the fresh cistanche deserticola and crush it with a crusher; use the wet method to break the wall of the prepared material; here it is represented by a colloid mill Conduct the test: mix the coarse powder and water at a weight ratio of 1:1, put them into the colloid mill, adjust the gap between the stator and the rotor of the colloid mill to 2-10 microns, and grind for 30 minutes to 90 minutes, depending on the model of the colloid mill : JMS-180, provided by Langfang Lijie Machinery Factory; then the prepared mixture of substances and liquids was sterilized by high-pressure treatment at 200Mpa (hydrostatic pressure) for 20 minutes, and the pressure was released instantly. The wall breaking rate was about 97%. The particle size diameter is about 1-3 microns, and the homogeneity reaches 98%. Finally, it is freeze-dried. Here, the low-temperature negative pressure d...

Embodiment 3

[0023] Embodiment 3 Weigh 500g Cistanche deserticola, wash and slice it, and dry it; the coarse powder or directly wash the fresh cistanche deserticola and break it with a crusher; use the wet method to break the wall of the prepared coarse powder; On behalf of the test;: mix the coarse powder and water with a weight ratio of 1:1, put it into the colloid mill to break the wall; adjust the gap between the colloid mill stator and the rotor to 2-10 microns, and grind for 30-90 minutes. The obtained mixture of substances and liquids was ultrasonically treated with an ultrasonic wall breaking machine, and an ultrasonic cell pulverizer SL-1200D provided by Nanjing Shunliu Instrument Co., Ltd. was used for 15-30 min with an ultrasonic wave of 10-60 kHz. In this way, the wall-breaking rate can be improved more effectively and the particle size can be minimized. The obtained material is sterilized under high-pressure treatment at 350Mpa (hydrostatic pressure) for 30 minutes, and the pre...

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Abstract

The invention relates to a cistanche cell disruption method which is characterized in that the method mainly comprises the following steps:1, conducting coarse powdering on cistanche slices, 2, conducting disruption on cistanche with a disruption technique, 3, conducting ultrahigh pressure treatment on the cistanche subjected to the disruption, and releasing pressure instantly, and 4, drying. Cistanche micropowder subjected to the disruption is high in disruption rate and very small in particle size. A buccal tablet is prepared by tabletting in a vacuum or nitrogen filled environment, the oxidation is avoided, the taking is facilitated, and the absorption of a human body is more facilitated.

Description

technical field [0001] The invention belongs to the technical field of medicinal plant application research, and in particular relates to a method for breaking cell walls of Cistanche deserticola and a buccal tablet prepared from the micropowder of Cistanche deserticola obtained by the method. Background technique [0002] Cistanche is the dried fleshy stem with scaly leaves of Cistanche deserticola (Cistanche deserticola Y.C.Ma). Cistanche is a parasitic plant that lives on the roots of desert trees Haloxylon and tamarisk. Distributed in Inner Mongolia, Ningxia, Gansu and Xinjiang, it is known as "Desert Ginseng" and has extremely high medicinal value. One of the most frequently used tonic drugs. It is tonic and soothing, and is more suitable for long-term use. And it contains a variety of nutrients, trace elements and vitamins that are useful to the human body. [0003] The consumption of cistanche is increasing year by year, but its output can not satisfy the speed of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/64A61K9/20A61P1/14A61P39/06A61P1/10
Inventor 孟令刚
Owner 孟令刚
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