Polydimethylsiloxane micro-fluidic chip and preparation method thereof
A technology of polydimethylsiloxane and polydimethylsiloxane materials, which is applied in the field of preparation of polydimethylsiloxane microfluidic chips, can solve the problem of poor bonding strength, easy leakage, Expensive and other issues, to achieve the effect of fast sealing and reversible bonding
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[0023] Example 1
[0024] figure 1 It is a schematic diagram of the cross-sectional structure of the polydimethylsiloxane microfluidic chip in Example 1 of the present invention.
[0025] in figure 1 Among them, the upper layer is a polydimethylsiloxane cover sheet layer, the middle layer is a double-sided adhesive layer, and the lower layer is a polydimethylsiloxane base layer. The microchannel of the microfluidic chip is directly processed on the double-sided adhesive material of the intermediate layer, and the specific method is: laser etching is used in the commercialized Transparent microchannel graphics are processed on the Tape type double-sided adhesive. The cover sheet layer and the base sheet layer are both mixed and degassed by the prepolymer of polydimethylsiloxane and the initiator in a ratio of 10:1. It is obtained by pouring on a flat glass sheet. After the solution inlet and outlet are punched out on the cover sheet layer with a puncher, the upper and lower polydi...
Example Embodiment
[0026] Example 2
[0027] figure 2 It is a schematic diagram of the cross-sectional structure of the polydimethylsiloxane microfluidic chip in Example 2 of the present invention.
[0028] in figure 2 Among them, the upper layer is a polydimethylsiloxane cover sheet layer, the middle layer is a double-sided adhesive layer, and the lower layer is a polydimethylsiloxane base layer. The microchannel of the microfluidic chip is directly processed on the polydimethylsiloxane siloxane material on the upper layer. The specific method is: using traditional micromachining methods to prepare a silicon template with micro-protrusions on a silicon substrate, and The prepolymer of polydimethylsiloxane and the initiator are mixed in a ratio of 10:1, degassed, and cast on a silicon template to obtain a microchannel substrate with a microgroove structure. The polydimethylsiloxane substrate of the lower layer is directly obtained by mixing the prepolymer of polydimethylsiloxane and the initiator ...
Example Embodiment
[0029] Example 3
[0030] image 3 It is a schematic diagram of the cross-sectional structure of the polydimethylsiloxane microfluidic chip in Example 2 of the present invention.
[0031] in image 3 Among them, the upper layer is a polydimethylsiloxane cover sheet layer, the middle layer is a double-sided adhesive layer, and the lower layer is a polydimethylsiloxane base layer. The microchannel of the microfluidic chip is directly processed on the lower layer of polydimethylsiloxane siloxane material. The specific method is: using traditional micromachining methods to prepare a silicon template with micro-protrusions on a silicon substrate. The prepolymer of polydimethylsiloxane and the initiator are mixed in a ratio of 10:1, degassed, and cast on a silicon template to obtain a microchannel substrate with a microgroove structure. The polydimethylsiloxane substrate of the upper layer is directly obtained by mixing the prepolymer of polydimethylsiloxane and the initiator in a rat...
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