The invention relates to a novel preparation method of
cicada slough cough-relieving granules, which comprises the following steps: taking
cicada slough,
scutellaria baicalensis,
lumbricus,
aster tataricus,
stemona and myrobalan, adding
ethanol, performing
reflux extraction, filtering, concentrating filtrate, and merging concentrated solutions to obtain an
alcohol extract and decoction dregs II; combining the
medicine residue II with the
medicine residue I of
schizonepeta, residual liquid and stiff silkworm, adding water, decocting, filtering, concentrating filtrate under reduced pressure, and combining concentrated solutions to obtain a water extract; and mixing the
alcohol extract and the water extract, and concentrating to obtain the
cicada slough cough-relieving granule extract. And carrying out one-step
granulation and
drying on the cicada slough cough-relieving granule extract, sieving and finishing granules, and totally mixing to obtain the cicada slough cough-relieving granules. According to the method, multiple processes of mixing, spraying, forming,
drying and the like are completed in one device, circulation of products among different devices is reduced, the risk of introducing microorganisms is reduced, the preparation time is shortened, the transfer rate of the index component
baicalin is obviously increased, operation is easy, the yield of finished products is increased, and the method is suitable for industrial production.